Current Search: Electronic Thesis or Dissertation (x) » Gunasekera, Sarath P. (x)
Pages
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Title
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Chemistry and biology of the discodermolides, potent mitotic spindle poisons.
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Creator
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Gunasekera, Sarath P., Wright, Amy E.
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Date Issued
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2005
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PURL
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http://purl.flvc.org/FCLA/DT/3352941
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Subject Headings
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Polyketides, Sponges, Immunosuppressive agents, Antimitotic agents, Chemistry, Biology
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Format
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Document (PDF)
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Title
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New acetylenic alcohols from the sponge Cribrochalina vasculum.
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Creator
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Gunasekera, Sarath P., Faircloth, G. T., Harbor Branch Oceanographic Institute
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Date Issued
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1990
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PURL
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http://purl.flvc.org/FCLA/DT/3332975
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Subject Headings
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Sponges, Alcohols, Acetylene compounds
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Format
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Document (PDF)
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Title
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Hamacanthins A and B. New antifungal bis indole alkaloids from the deep-water marine sponge, Hamacantha sp.
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Creator
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Gunasekera, Sarath P., McCarthy, Peter J., Kelly-Borges, M.
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Date Issued
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1994
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PURL
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http://purl.flvc.org/FCLA/DT/3319078
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Subject Headings
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Sponges --Research, Indole alkaloids, Marine natural products, Antifungal agents
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Format
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Document (PDF)
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Title
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Dysidiolide: a novel protein phosphatase inhibitor from the Caribbean sponge Dysidea etheria de Laubenfels.
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Creator
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Gunasekera, Sarath P., McCarthy, Peter J., Kelly-Borges, M., Lobkovsky, E., Clardy, J.
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Date Issued
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1996
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PURL
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http://purl.flvc.org/FCLA/DT/3319096
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Subject Headings
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Sponges --Research, Dysidiolide, Marine metabolites, Marine natural products, Protein phosphatases
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Format
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Document (PDF)
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Title
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Antimicrobial constituent of the brown alga Sporochnus pedunculatus.
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Creator
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Gunasekera, L. S., Wright, Amy E., Gunasekera, Sarath P., McCarthy, Peter J., Reed, John K.
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Date Issued
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1995
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PURL
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http://purl.flvc.org/fau/fd/FA00007231
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Subject Headings
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Brown algae, Antimicrobial agents, Nuclear magnetic resonance, Candida albicans, Bacillus subtilis
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Format
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Document (PDF)
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Title
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A novel activity from an old compound: Manzamine A reduces the metastatic potential of AsPC-1 pancreatic cancer cells and sensitizes them to TRAIL-induced apoptosis.
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Creator
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Guzman, Esther A., Johnson, J. D., Linley, P. A., Wright, Amy E., Gunasekera, Sarath P.
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Date Issued
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2010
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PURL
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http://purl.flvc.org/FCLA/DT/3318907
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Subject Headings
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Pancreas--Cancer, Apoptosis, Sponges--Research, Marine natural products, Drug Discovery
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Format
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Document (PDF)
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Title
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Dercitin, a new biologically active acridine alkaloid from a deep water marine sponge, Dercitus sp.
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Creator
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Gunawardana, G. P., Kohmoto, S., Gunasekera, Sarath P., McConnell, O. J., Koehn, F. E., Harbor Branch Oceanographic Institute
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Date Issued
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1988
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PURL
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http://purl.flvc.org/FCLA/DT/3332948
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Subject Headings
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Sponges, Alkaloids, Acridine, Marine toxins
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Format
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Document (PDF)
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Title
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Synthesis of microcolin analogs using trimethylsilylated lactams.
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Creator
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Mattern, R.-H., Gunasekera, Sarath P., McConnell, O. J., Harbor Branch Oceanographic Institute
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Date Issued
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1997
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PURL
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http://purl.flvc.org/FCLA/DT/3331922
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Subject Headings
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Oligopeptides, Immunosuppressive agents, Cytotoxin, Lactams, Peptides--Synthesis
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Format
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Document (PDF)
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Title
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Antitumor activity and biochemical effects of topsentin.
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Creator
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Burres, N. S., Barber, D. A., Gunasekera, Sarath P., Clement, J. J., Shen, L. L.
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Date Issued
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1991
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PURL
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http://purl.flvc.org/FCLA/DT/3355144
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Subject Headings
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Marine natural products, Antitumor agents
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Format
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Document (PDF)
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Title
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Halitunal, an unusual diterpene aldehyde from the marine alga Halimeda tuna.
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Creator
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Koehn, F. E., Gunasekera, Sarath P., Niel, D. N., Cross, S. S., Harbor Branch Oceanographic Institute
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Date Issued
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1991
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PURL
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http://purl.flvc.org/FCLA/DT/3353864
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Subject Headings
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Halimeda, Green algae, Microalgae, Diterpenes, Antiviral agents
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Format
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Document (PDF)
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Title
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Ophirapstanol trisulfate, a new biologically active steroid sulfate from the deep water marine sponge Topsentia ophiraphidites.
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Creator
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Gunasekera, Sarath P., Sennett, Susan H., Kelly-Borges, M., Bryant, R. W., Harbor Branch Oceanographic Institute
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Date Issued
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1994
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PURL
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http://purl.flvc.org/FCLA/DT/3319079
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Subject Headings
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Sponges --Research, Marine natural products, NMR spectroscopy
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Format
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Document (PDF)
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Title
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Five new Discodermolide analogues from the marine sponge Discodermia species.
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Creator
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Gunasekera, Sarath P., Paul, Gopal K., Longley, Ross E., Isbrucker, Richard A., Pomponi, Shirley A.
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Date Issued
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2002
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PURL
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http://purl.flvc.org/FCLA/DT/3319106
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Subject Headings
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Sponges --Research, Cytotoxin, Marine natural products, Polyketides
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Format
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Document (PDF)
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Title
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Bioassay-guided isolation and identification of linoleic acid: A guanosine diphosphate/G-protein RASexchange (GDPX) inhibitor from Aspergillus.
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Creator
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Gunasekera, Sarath P., Sennett, Susan H., Janda, Kathleen E., Bryant, R. W., Harbor Branch Oceanographic Institute
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Date Issued
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1995
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PURL
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http://purl.flvc.org/fau/fd/FA00007232
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Subject Headings
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Aspergillus, Linoleic acid, Biological Assay
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Format
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Document (PDF)
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Title
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Differential effects of domoic acid and E. coli lipopolysaccharide ontumor necrosis factor-α, transforming growth factor-β1 and matrix metalloproteinase-9 release by ratneonatal microglia: evaluation of the direct activation hypothesis.
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Creator
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Mayer, A. M. S., Guzman, M., Peksa, R., Hall, Mary, Fay, M. J., Jacobson, P. B., Romanic, A. M., Gunasekera, Sarath P., Harbor Branch Oceanographic Institute
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Date Issued
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2007
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PURL
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http://purl.flvc.org/fau/fd/FA00007282
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Subject Headings
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Domoic acid, Escherichia coli, Lipopolysaccharides, Endotoxins, Microglia
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Format
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Document (PDF)
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Title
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Synthetic studies of microcolin B.
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Creator
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Mattern, R.-H., Gunasekera, Sarath P., McConnell, O. J., Harbor Branch Oceanographic Institute
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Date Issued
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1995
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PURL
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http://purl.flvc.org/FCLA/DT/3331904
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Subject Headings
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Oligopeptides, Cytotoxin, Immunosuppressive agents, Biologically active compounds, Lyngbya, Blue-green algae
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Format
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Document (PDF)
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Title
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Synthetic Analogues of the Microtubule-Stabilizing Agent (+)-Discodermolide: Preparation and Biological Activity.
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Creator
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Gunasekera, Sarath P., Mickel, Stuart J., Daeffler, Robert, Niederer, Daniel, Wright, Amy E., Linley, P. A., Pitts, Tara P.
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Date Issued
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2004
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PURL
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http://purl.flvc.org/FCLA/DT/3164107
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Subject Headings
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Microtubules, Cancer --Research, Biopharmaceutics, Molecular biology, Stereochemistry
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Format
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Document (PDF)
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Title
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Discodermide: a new bioactive macrocyclic lactam from the marine sponge Discodermia dissoluta.
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Creator
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Gunasekera, Sarath P., Gunasekera, M., McCarthy, Peter J.
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Date Issued
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1991
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PURL
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http://purl.flvc.org/FCLA/DT/3332985
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Subject Headings
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Sponges, Lactams, Macrocyclic, Marine natural products
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Format
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Document (PDF)
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Title
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Two new bioactive cyclic peroxides from the marine sponge Plakortis angulospiculatus.
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Creator
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Gunasekera, Sarath P., Gunasekera, M., Gunawardana, G. P., McCarthy, Peter J., Burres, N. S.
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Date Issued
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1990
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PURL
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http://purl.flvc.org/FCLA/DT/3332965
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Subject Headings
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Sponges, Peroxides, Bioactive compounds, Antifungal agents, Cytotoxin, Marine metabolites
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Format
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Document (PDF)
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Title
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Selective cytotoxic activity of the marine derivedbatzelline compounds against pancreatic cancer cell lines.
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Creator
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Guzman, Esther A., Johnson, J. D., Carrier, M. K., Meyer, C. I., Pitts, Tara P., Gunasekera, Sarath P., Wright, Amy E.
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Date Issued
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2009
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PURL
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http://purl.flvc.org/fau/fd/FA00007114
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Subject Headings
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Pancreas--Cancer, Marine natural products, Drug Discovery, Sponges--Caribbean Sea, Mechanism of action (Biochemistry)
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Format
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Document (PDF)
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Title
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Antitumor tetrahydroisoquinoline alkaloids from the colonial ascidian Ecteinascidia turbinata.
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Creator
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Wright, Amy E., Forleo, D. A., Gunawardana, G. P., Gunasekera, Sarath P., Koehn, F. E., McConnell, O. J.
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Date Issued
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1990
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PURL
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http://purl.flvc.org/FCLA/DT/3332974
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Subject Headings
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Ascidians, Perophoridae (Tunicata), Tetrahydroisoquinolines, Alkaloids, Antineoplastic agents
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Format
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Document (PDF)
Pages