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- Title
- Diatoms as a food source for Sorites dominicensis.
- Creator
- Gaston, Tiffany., Harriet L. Wilkes Honors College
- Abstract/Description
-
Sorites dominicensis is a common Foraminifera living on Thalassia testudinum seagrass blades in the Indian River Lagoon. This locality is unique because epiphytic diatoms, characteristic of Caribbean and temperate environments, are expected to make up the biofilm community. Diatoms compose a large part of the Foraminiferan diet. It is important to understand the cause and effect relationship of population variation between S. dominicensis and its preferred food source, since both are valuable...
Show moreSorites dominicensis is a common Foraminifera living on Thalassia testudinum seagrass blades in the Indian River Lagoon. This locality is unique because epiphytic diatoms, characteristic of Caribbean and temperate environments, are expected to make up the biofilm community. Diatoms compose a large part of the Foraminiferan diet. It is important to understand the cause and effect relationship of population variation between S. dominicensis and its preferred food source, since both are valuable bioindicators. We examined the selective feeding of S. dominicensis by first, identifying the diatom assemblage. Second, we utilized scanning electron microscopy (SEM) in order to identifying the remains of diatoms entrapped in pseudopodial nets and in debris piles. We found that Mastogloia and Cocconeis were the most prominent genera in the overall diatom assemblage. The food preference of S. dominicensis included Amphora, Berkeleya rutilans,Cocconeis, Licmophora dalmatica, Mastogloia, Odontella rhombus, Plagiogramma pulchellum var. pygmaeum, and Skeletonema.
Show less - Date Issued
- 2008
- PURL
- http://purl.flvc.org/FAU/77667
- Subject Headings
- Diatoms, Identification, Wetland ecology, Stream ecology, Methodology
- Format
- Document (PDF)
- Title
- Iron and mitochondrial aging.
- Creator
- Paez, Rafael., Harriet L. Wilkes Honors College
- Abstract/Description
-
Aging is a process characterized by accumulated oxidative damage to DNA, proteins, and lipids,which leads to the gradual degeneration of cellular activity. Mitochondria play a central role in aging because they produce both cellular energy and oxidative stress. As resultof accumulated oxidative damage, mitochondria function decays, which leads to a cellular energy deficit and compromises cellular function. Iron is an essential nutrient reequired by mitodhondria to function optimally. It has...
Show moreAging is a process characterized by accumulated oxidative damage to DNA, proteins, and lipids,which leads to the gradual degeneration of cellular activity. Mitochondria play a central role in aging because they produce both cellular energy and oxidative stress. As resultof accumulated oxidative damage, mitochondria function decays, which leads to a cellular energy deficit and compromises cellular function. Iron is an essential nutrient reequired by mitodhondria to function optimally. It has been proved that iron supplementation increases the lifespan of several yeast strains, including superoxide dismutase mutants. We are interested in finding where the iron is going and what it might be doing that is beneficial to the cell. We have used Saccharomyces cerevisiae as our molecular model of aging. Our results indicate that the extra iron is being transported into the mitochoindria.
Show less - Date Issued
- 2012
- PURL
- http://purl.flvc.org/FAU/3359313
- Subject Headings
- Oxidation, Physiological, Aging, Molecular aspects, Mitochondrial DNA, Yeast fungi, Research, Methodology, Free radicals (Chemistry), Pathophysiology
- Format
- Document (PDF)
- Title
- Creation of an aconitase overexpression strain of Saccharomyces cerevisiae for lifespan analysis.
- Creator
- Nunes, Steve., Harriet L. Wilkes Honors College
- Abstract/Description
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In my thesis work, I attempted to construct a plasmid that would allow stable integration of genes into the Saccharomyces cerevisiae yeast genome under the control of the repressible TetO promoter. The yeast ACO1 gene was cloned under the control of the TetO operator and the tTA transactivator. This construct was inserted into yeast cells in order to observe the effects of aconitase overexpression on aging. Unfortunately, the transformed cells appeared incapable of aconitase expression as...
Show moreIn my thesis work, I attempted to construct a plasmid that would allow stable integration of genes into the Saccharomyces cerevisiae yeast genome under the control of the repressible TetO promoter. The yeast ACO1 gene was cloned under the control of the TetO operator and the tTA transactivator. This construct was inserted into yeast cells in order to observe the effects of aconitase overexpression on aging. Unfortunately, the transformed cells appeared incapable of aconitase expression as determined by glutamic acid auxptrophy, a phenotype of aconitase mutants. We have sequenced the pIT1ACO1 plasmid and have found many abnormalities in the promoter region. If the plasmid can be made to function as intended, the resulting yeast strain can be used in the future to determine if aconitase plays an important role in cellular aging.
Show less - Date Issued
- 2012
- PURL
- http://purl.flvc.org/FAU/3359306
- Subject Headings
- Yeast fungi, Research, Methodology, Microbial genetics, Genetic engineering, Aging, Molecular aspects, Cell metabolism, Mutation (Biology)
- Format
- Document (PDF)
- Title
- An empirical analysis of the roles assumed by public administrators: the case of public procurement specialists.
- Creator
- Roman, Alexandru V., College for Design and Social Inquiry, School of Public Administration
- Abstract/Description
-
This dissertation examines administrative roles within the context of everyday public administration. Specifically, it studies the relationship between administrative roles assumed by public administrators and (1) the perceived presence of administrative discretion, (2) individual level beliefs regarding involvement in policy formulation and (3) tenure with organization. This dissertation has a three-fold purpose. First, it delineates the types of roles assumed by public procurement...
Show moreThis dissertation examines administrative roles within the context of everyday public administration. Specifically, it studies the relationship between administrative roles assumed by public administrators and (1) the perceived presence of administrative discretion, (2) individual level beliefs regarding involvement in policy formulation and (3) tenure with organization. This dissertation has a three-fold purpose. First, it delineates the types of roles assumed by public procurement specialists. Second, it tests whether administrative discretion, beliefs regarding participation in policy formulation and organizational tenure are significant in explaining the assumption of certain types of roles. Finally, the dissertation evaluates the implications for the public procurement process of the predominance of certain roles. vi The theoretical logic for this dissertation draws on the theory of representative bureaucracy and role theory. ... It is found that administrative discretion, individual expectations and organizational tenure are indeed important predictors of the assumption of administrative roles. Administrators who believe that they have access to relatively high levels of discretion and those who believe they should be involved in policy formulation are more likely to assume a representative type role. On the other hand, with increased tenure public administrators are less likely to assume a representative type role.
Show less - Date Issued
- 2013
- PURL
- http://purl.flvc.org/fcla/dt/3362569
- Subject Headings
- Public administration, Methodology, Transparency in government, Comparative government, Bureaucracy
- Format
- Document (PDF)
- Title
- Evaluation of surface dose outside the treatment area for breast cancer irradiation modalities using thermoluminescence dosimeters (TLDs).
- Creator
- Khanal, Suraj P., Charles E. Schmidt College of Science, Department of Physics
- Abstract/Description
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The purpose of this research is to compare the surface dose outside the treatment area for different breast cancer irradiation modalities using Thermoluminescence Dosimeters (TLDs). Five different modalities are included in this study: Accuboost, Photon boost, Electron boost, Strut-Adjusted Volume Implant (SAVI), and Mammosite Multi-lumen (ML).Six points of interest (POI) on the breast cancer patients had been selected for the TLDs placement. Data from 25 breast cancer patients at Lynn Cancer...
Show moreThe purpose of this research is to compare the surface dose outside the treatment area for different breast cancer irradiation modalities using Thermoluminescence Dosimeters (TLDs). Five different modalities are included in this study: Accuboost, Photon boost, Electron boost, Strut-Adjusted Volume Implant (SAVI), and Mammosite Multi-lumen (ML).Six points of interest (POI) on the breast cancer patients had been selected for the TLDs placement. Data from 25 breast cancer patients at Lynn Cancer Institute of the Boca Raton Regional Hospital were included in the study. The measured percentage ranges of the averaged doses at the six POIs for the different modalities are: Sternum 0.26% - 3.26%, Shoulder 0.33% - 2.79%, Eye 0.26% - 1.32%, Thyroid 0.20% - 2.75%, CLB 0.2% - 5.46%, Lower Abdomen 0.16% - 2.25%.
Show less - Date Issued
- 2013
- PURL
- http://purl.flvc.org/fcla/dt/3362479
- Subject Headings
- Thermoluminescence, Therapeutic use, Radiation dosimetry, Breast, Cancer, Treatmernt, Radiation, Measurement, Methodology
- Format
- Document (PDF)
- Title
- DNAJC25 Pro90Leu J-domain mutation demonstrates decreased chaperone activity in vitro.
- Creator
- Chauss, Daniel C., Charles E. Schmidt College of Medicine, Department of Biomedical Science
- Abstract/Description
-
Molecular chaperones guide peptide fold conformation throughout the lifetime of the peptide. One network of chaperone proteins involved in this activity, Heat shock protein 70s (Hsp70s), are well characterized at restoring peptide fold, utilizing J-domain containing protein chaperone cofactors to activate Hsp70 activity. DnaJ (Hsp40) homolog, subfamily C, member 25 (DNAJC25) is a class III transmembrane J-domain containing protein that to date is underrepresented in the literature. Recently,...
Show moreMolecular chaperones guide peptide fold conformation throughout the lifetime of the peptide. One network of chaperone proteins involved in this activity, Heat shock protein 70s (Hsp70s), are well characterized at restoring peptide fold, utilizing J-domain containing protein chaperone cofactors to activate Hsp70 activity. DnaJ (Hsp40) homolog, subfamily C, member 25 (DNAJC25) is a class III transmembrane J-domain containing protein that to date is underrepresented in the literature. Recently, Hejtmancik et al. 2012. (unpublished data) have revealed that missense mutation to DNACJ25 at Pro90Leu (P90L) is strongly correlated with inherited Closed-Angle Glaucoma. Inherited mutations are well characterized for Open-Angle Glaucoma, however, prior to this finding, were unknown for Closed-Angle Glaucoma. In this report, analysis of the in vitro chaperone activity of DNAJC25 w+ and P90L is assessed utilizing an Hsp70 mediated Glucose-6-Phosphate Dehydrogenase refolding system, SWISS-MODEL predictions are performed for the J-domain structure of DNAJC25 w+ and P90L with consequent analysis of DNAJC25 Pro90 conservation relative to other type I, II, and III J-domain containing proteins. DNAJC25 P90L demonstrated decreased chaperone activity in vitro compared to w+ DNAJC25.
Show less - Date Issued
- 2012
- PURL
- http://purl.flvc.org/FAU/3342040
- Subject Headings
- Cell physiology, Methodology, Molecular chaperones, Physiological effect, Cellular signal transduction, Proteolytic enzymes
- Format
- Document (PDF)
- Title
- Cyclic lipodepsipeptides as lead structures for the discovery of new antiobiotics.
- Creator
- Bionda, Nina., Charles E. Schmidt College of Science, Department of Chemistry and Biochemistry
- Abstract/Description
-
With antimicrobial resistance to current drugs steadily rising, the development of new antibiotics with novel mechanisms of action has become an imperative. The majority of life-threatening infections worldwide are caused by "ESKAPE" pathogens which are encountered in more than 40% of hospital-acquired infections, and are resistant to the majority of commonly used antibiotics. Naturally occurring cyclic depsipeptides, microbial secondary metabolites that contain one or more ester bonds in...
Show moreWith antimicrobial resistance to current drugs steadily rising, the development of new antibiotics with novel mechanisms of action has become an imperative. The majority of life-threatening infections worldwide are caused by "ESKAPE" pathogens which are encountered in more than 40% of hospital-acquired infections, and are resistant to the majority of commonly used antibiotics. Naturally occurring cyclic depsipeptides, microbial secondary metabolites that contain one or more ester bonds in addition to amide bonds, have emerged as an important source of pharmacologically active compounds or lead structures for the development of novel antibiotics. Some of those peptides are either already marketed (daptomycin) or in advanced stages of clinical development (ramoplanin). Structurally simple, yet potent, fusaricidin/LI-F and lysobactin families of naturally occurring antibiotics represent particularly attractive candidates for the development of new antibacterial agents capable of overco ming infections caused by multidrug-resistant bacteria. These natural products exhibit potent antimicrobial activity against a variety of clinically relevant fungi and Gram-positive bacteria. Therefore, access to these classes of natural products and their synthetic analogs, combined with elucidation of their mode of action represent important initial steps toward full exploitation of their antmicrobial potential. This dissertation describes a general approach toward the solid-phase synthesis of fusaricidin/LI-F and lysobactin analogs and an extensive structure-activity relationship (SAR) study. We have devised a simple and robust preparation strategy based on standard Fmoc solid-phase peptide synthesis protocols., The SAR study revealed key structural requirements for fusaricidin/LI-F and related cyclic lipopeptides antibacterial activity, including the presence of the guanidino moietly at the end of the lipidic tail, hydrophobic amino acid residues, and peptide conformation Moreover, substitution of the ester bond with an amide bond significantly improved stability under physiologically relevant conditions and reduced toxicity. In addition, we have shown that these antibacterial peptides exert their mode of action via a novel mechanism, which invloves bacterial membrane interactions, followed by peptide internalization. Altogether, the research described in this dissertation demonstrates that new antibiotics derived from fusaricidin/LI-F natural products, have the potential to meet the challenge of antibiotic resistance in Gram-positive bacteria.
Show less - Date Issued
- 2013
- PURL
- http://purl.flvc.org/FAU/3360768
- Subject Headings
- Microbial peptides, Drugs, Design, Peptides, Therapeutic use, Genetic engineering, Antibacterial agents, Peptide antibiotics, Research, Methodology, Peptide antibiotics, Analysis
- Format
- Document (PDF)
- Title
- Does obesity affect the accuracy of age-at-death estimation using the pubic symphysis and auricular surface?.
- Creator
- Drew, Jessica L., Dorothy F. Schmidt College of Arts and Letters, Department of Anthropology
- Abstract/Description
-
This study examines whether obesity affects the accuracy of estimating age-at-death as measured by the age-related changes of the pubic symphysis and auricular surfaces. I scored the hip bones of 119 adults of normal body mass and 126 obese adults (total n = 254) using the SucheyBrooks (1990) method for the pubic symphysis and the Buckberry and Chamberlain (2002) method for the auricular surface. Compared to normal weight individuals, obese individuals exhibited greater inaccuracy in age-at...
Show moreThis study examines whether obesity affects the accuracy of estimating age-at-death as measured by the age-related changes of the pubic symphysis and auricular surfaces. I scored the hip bones of 119 adults of normal body mass and 126 obese adults (total n = 254) using the SucheyBrooks (1990) method for the pubic symphysis and the Buckberry and Chamberlain (2002) method for the auricular surface. Compared to normal weight individuals, obese individuals exhibited greater inaccuracy in age-at-death estimates when aged from the auricular surface, but not the pubic symphysis. However, age was estimated with less precision in obese individuals using both methods. Obese males are more likely to be aged inaccurately than obese females. The pubic symphysis method may be the preferred method when estimating age in obese individuals, especially males, but forensic anthropologists should use caution when assessing age-at-death in obese adults using either method.
Show less - Date Issued
- 2010
- PURL
- http://purl.flvc.org/FAU/1927862
- Subject Headings
- Obesity, Physiological aspects, Skeletal maturity, Anthropometry, Methodology, Aging, Physiological aspects, Diet in disease
- Format
- Document (PDF)
- Title
- Effects of glycosylation on melanoma interactions with type IV collagen models.
- Creator
- Aukszi, Beatrix., Florida Atlantic University, Charles E. Schmidt College of Science, Department of Chemistry and Biochemistry
- Abstract/Description
-
Tumor cells interact with basement membrane collagen at the site of extravasation through distinct cellular receptors, including the α2β1 and α3β1integrins. These receptors are known to be differentially expressed in metastatic tumors, relative to the normal cells, depending on tumor type and stage of progression. The binding sites within type IV collagen for the α2β1 andα3β1 integrins have been identified. Since both of the integinspecific sequences possess at least one glycosylated Hyl...
Show moreTumor cells interact with basement membrane collagen at the site of extravasation through distinct cellular receptors, including the α2β1 and α3β1integrins. These receptors are known to be differentially expressed in metastatic tumors, relative to the normal cells, depending on tumor type and stage of progression. The binding sites within type IV collagen for the α2β1 andα3β1 integrins have been identified. Since both of the integinspecific sequences possess at least one glycosylated Hyl residue, we questioned whether glycosylation could modulate integrin binding. Triple-helical peptides with and without Lys substituted by glycosylated Hyl for Lys543 and Lys540 from the human a1(IV)531-543 gene sequence (α3β integrin-specific) and Lys393 from the human a1(IV)382-393 gene sequence (α2β1 integrin-specific) were synthesized and utilized in the present study., Cellular response to these triple helical ligands was tested with a primary melanoma cell line, WM-115, and three highly metastatic melanoma cell lines , WM-266-4, M14#5, and SK-MEL-2. Cell adhesion and cell spreading assays yielded differing results depending on whether the ligands contained glycosylated Hyl residues or not. In general, a decrease in cellular affinity toward the ligands was observed when glycosylated Hyl was present. Differences in the levels of adhesion and spreading between cell lines representing different stages of melanoma were also observed. Neutral B-galactosidase activity was detected in all four cell lines. Enzymatic activity levels were comparable for the three metastatic cell lines, whereas distinctively higher activity was detected for cells originating from a primary lesion. This acitivity can signal the potential of tumor cells to enhance and recover their invasive abilities., The ability of each cell line to remove the galactose from the peptide ligands has been investigated, to test whether tumor cells can reestablish binding relationships between the α2β1 and α3β1 integrins and type IV collagen that are reduced by glycosylation.
Show less - Date Issued
- 2008
- PURL
- http://purl.flvc.org/FAU/186335
- Subject Headings
- Animal cell biotechnology, Combinatorial chemistry, Integrins, Research, Methodology, Cell adhesion molecules, Physiological effect
- Format
- Document (PDF)
- Title
- First year undergraduate students' perception of the effectiveness and transfer of multimedia training for a university course registration system.
- Creator
- Dee, Merideth I., College of Education, Department of Educational Leadership and Research Methodology
- Abstract/Description
-
The purpose of this study was to evaluate the perceived effectiveness of a multimedia tutorial for first year undergraduate students (FTICs) using a university course registration system; to determine if a relationship existed between perceived effectiveness of the multimedia tutorial, gender, major, ICT usage, ICT education, ICT fluency, and ICT comfort; and to describe the transfer of learning, if any, that resulted from viewing the multimedia tutorial. The study was both quantitative and...
Show moreThe purpose of this study was to evaluate the perceived effectiveness of a multimedia tutorial for first year undergraduate students (FTICs) using a university course registration system; to determine if a relationship existed between perceived effectiveness of the multimedia tutorial, gender, major, ICT usage, ICT education, ICT fluency, and ICT comfort; and to describe the transfer of learning, if any, that resulted from viewing the multimedia tutorial. The study was both quantitative and qualitative in design addressing 10 research questions. The instruments used in this study consisted of the Registration Tutorial which included: (1) an Information and Communication Technology (ICT) Fluency Questionnaire (Hilberg, 2007), (2) a multimedia tutorial designed by the researcher demonstrating the university course registration system, and (3) the Registration Video Questionnaire (RVQ) also designed by the researcher measuring perceived multimedia tutorial effectiveness. A Registration Video Tutorial Transfer of Learning Questionnaire (TLQ) was also developed by the research to measure perceived proficiency with the registration system three months after initially viewing the multimedia tutorial. The sample included 1,196 freshmen students from a large public university in the southeastern United States. Results of the study showed that students perceived the multimedia tutorial to be effective (M = 4.19, SD = .756) and seven themes emerged through qualitative analysis as to why the tutorial was or was not effective. Results also showed there was no relationship between multimedia tutorial effectiveness and gender, major, or ICT education., There were however significant weak relationships between multimedia tutorial effectiveness and ICT usage (r = .095), multimedia tutorial effectiveness and ICT fluency (r = .286), and multimedia tutorial effectiveness and ICT comfort (r = -.133). Furthermore, transfer of learning occurred for students (n = 66) who completed the TLQ (M = 4.01, SD =.777) and as suggested by qualitative analysis of student responses. Implications of this study suggested that providing first year undergraduate students with a web-based multimedia tutorial is just the beginning and the need may be to focus upon the development of these students as adult learners so they can feel successful in the early stages of their academic career, thus building the self-confidence they need to effectively navigate the university environment.
Show less - Date Issued
- 2011
- PURL
- http://purl.flvc.org/FAU/3170600
- Subject Headings
- Interactive multimedia, Academic achievement, Methodology, Computers and college students, Education, Highter, Effect of technological innovations on
- Format
- Document (PDF)
- Title
- Gene selection for sample sets with biased distribution.
- Creator
- Kamal, Abu Hena Mustafa., College of Engineering and Computer Science, Department of Computer and Electrical Engineering and Computer Science
- Abstract/Description
-
Microarray expression data which contains the expression levels of a large number of simultaneously observed genes have been used in many scientific research and clinical studies. Due to its high dimensionalities, selecting a small number of genes has shown to be beneficial for many tasks such as building prediction models from the microarray expression data or gene regulatory network discovery. Traditional gene selection methods, however, fail to take the class distribution into the...
Show moreMicroarray expression data which contains the expression levels of a large number of simultaneously observed genes have been used in many scientific research and clinical studies. Due to its high dimensionalities, selecting a small number of genes has shown to be beneficial for many tasks such as building prediction models from the microarray expression data or gene regulatory network discovery. Traditional gene selection methods, however, fail to take the class distribution into the selection process. In biomedical science, it is very common to have microarray expression data which is severely biased with one class of examples (e.g., diseased samples) significantly less than other classes (e.g., normal samples). These sample sets with biased distributions require special attention from researchers for identification of genes responsible for a particular disease. In this thesis, we propose three filtering techniques, Higher Weight ReliefF, ReliefF with Differential Minority Repeat and ReliefF with Balanced Minority Repeat to identify genes responsible for fatal diseases from biased microarray expression data. Our solutions are evaluated on five well-known microarray datasets, Colon, Central Nervous System, DLBCL Tumor, Lymphoma and ECML Pancreas. Experimental comparisons with the traditional ReliefF filtering method demonstrate the effectiveness of the proposed methods in selecting informative genes from microarray expression data with biased sample distributions.
Show less - Date Issued
- 2009
- PURL
- http://purl.flvc.org/FAU/186330
- Subject Headings
- Gene expression, Research, Methodology, Medical informatics, Apoptosis, Molecular aspects, DNA microarrays, Research
- Format
- Document (PDF)
- Title
- Affect coding within the therapeutic relationship.
- Creator
- Luedke, Ashley J., College of Education, Department of Counselor Education
- Abstract/Description
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This study investigates affect coding within the therapeutic relationship, by exploring the client's and therapist's perception of the relationship and the facial and vocal affect expressed by both parties. A sample of 14 therapy sessions each having 1800 data points was collected. The Working Alliance Inventory Short Form (WAI-S) and Real Relationship Inventory (RRI) were completed after each recorded session. The participants were therapists and clients at a university counseling center in...
Show moreThis study investigates affect coding within the therapeutic relationship, by exploring the client's and therapist's perception of the relationship and the facial and vocal affect expressed by both parties. A sample of 14 therapy sessions each having 1800 data points was collected. The Working Alliance Inventory Short Form (WAI-S) and Real Relationship Inventory (RRI) were completed after each recorded session. The participants were therapists and clients at a university counseling center in South Florida. Data were analyzed using one-tailed t tests, descriptive statistics, scores from RRI and the WAI-S and percentages of negative, neutral and positive affect. Statistically significant relationships were found between seconds of therapist negative affect (t(13)= -2.065, p. <.05) and seconds of therapist neutral affect (t(13)= -1.959, p. <.05) for clients who dropped out of therapy. The seconds of negative affect coded for clients (t(13) = -1.396, p. >.05) was approaching statistical significance for clients who drop out of therapy. This study provides theoretical and empirical support for linking the presence of facial affect in the first session and its effects on the therapeutic relationship and thus client retention or drop out. The clinical implications of these findings are also discussed.
Show less - Date Issued
- 2013
- PURL
- http://purl.flvc.org/fcla/dt/3362484
- Subject Headings
- Cognitive neuroscience, Interpersonal communication, Body language, Research, Methodology, Affect (Psychology), Psychotherapist and patient
- Format
- Document (PDF)
- Title
- Advanced Placement (AP) social studies teachers' use of academic course blogs as a supplemental resource for student learning.
- Creator
- Alper, Seth., College of Education, Department of Curriculum, Culture, and Educational Inquiry
- Abstract/Description
-
This mixed-methods study investigated the relationship between Advanced Placement (AP) social studies teachers' utilization of academic course blogs and student achievement. Simultaneously, the study examined the participating teachers' perceptions on the use of course blogs and other social media as supplemental learning resources. The study further explored a possible moderating effect of the social studies subject on student achievement and a possible moderating effect of students'...
Show moreThis mixed-methods study investigated the relationship between Advanced Placement (AP) social studies teachers' utilization of academic course blogs and student achievement. Simultaneously, the study examined the participating teachers' perceptions on the use of course blogs and other social media as supplemental learning resources. The study further explored a possible moderating effect of the social studies subject on student achievement and a possible moderating effect of students' previous academic blog usage on student achievement within the study. Quantitative data were collected from students' pre-tests and unit tests scores and analyzed for statistical significance. Qualitative data were collected through teacher-generated notes during the blogs, individual interviews, and a follow-up focus group interview. The results of this study indicated that there was no overall significant difference in student achievement between the blogging and non-blogging groups. On the contrary , a significant interaction between the social studies subject area and the use of academic course blogs was found when examining student achievement. However, this practical interaction was revealed to be a weak one. Further findings indicated that there was no significant interaction between students' previous blog usage and academic achievement during the study. From the qualitative data, participating teachers perceived the course blogs to be potentially advantageous for students and themselves, yet expressed frustration when implementing the course blogs with their students. Instead, they endorsed the academic use of Facebook, a resource that some students from two participating courses separately utilized instead of (or in addition to) the course blogs during the study. Teachers further expressed concern about relinquishing their subject knowledge and AP expertise to readily available course content on the Internet. Implications and suggestions for future f or AP social studi, teachers' promising use of Facebook and for researchers investigating the use of socail media at the high school level.
Show less - Date Issued
- 2013
- PURL
- http://purl.flvc.org/FAU/3360744
- Subject Headings
- Social sciences, Study and teaching (Secondary), Methodology, Information resources, Evaluation, Internet in education, Social aspects, Constructivism (Education)
- Format
- Document (PDF)
- Title
- ASHA-certified speech-language pathologists: informal learning in the medical workplace.
- Creator
- Walden, Patrick Roy., College of Education, Department of Educational Leadership and Research Methodology
- Abstract/Description
-
This study explored the types and uses of informal, on-the-job learning occurring among American Speech-Language-Hearing (ASHA)-certified Speech-Language Pathologists (SLPs) working in medical settings as part of a rehabilitation team. In addressing this purpose, a qualitative, phenomenological approach to research methodology was used. Participants were selected through a process of purposeful sampling, each meeting the criteria of having earned the Certificate of Clinical Competence in...
Show moreThis study explored the types and uses of informal, on-the-job learning occurring among American Speech-Language-Hearing (ASHA)-certified Speech-Language Pathologists (SLPs) working in medical settings as part of a rehabilitation team. In addressing this purpose, a qualitative, phenomenological approach to research methodology was used. Participants were selected through a process of purposeful sampling, each meeting the criteria of having earned the Certificate of Clinical Competence in Speech-Language Pathology from ASHA and working in a medical setting as part of a rehabilitation team. Twenty-four SLPs from varying demographic profiles took part in one of three online data collection methods. Nine participants completed a computer-mediated interview, 11 participants completed an online journal entry and 4 participants completed a virtual focus group method. All data collection methods were accomplished via internet technologies. Data analysis was performed through a process of thematic analysis and resulted in four significant findings. First, both internal and external forces triggered SLPs to learn informally in the medical workplace. Also, SLPs went through an individually-determined, goal-directed process when learning informally in the medical workplace. SLPs used a combination of collaboration, workplace experience and research to learn informally in the medical workplace. And finally, SLPs employed informal learning activities for the purpose of meeting personal, patient and organizational needs., It was recommended that (a) the American Speech- Language-Hearing Association review its professional development policy and consider implementation of a process whereby clinicians can document their goal-directed workplace learning and receive professional development credit for these activities; (b) healthcare organizations recognize, support and reward the informal learning in which their SLPs are already engaging; and (c) SLPs enhance their informal learning in the medical workplace through proactivity, critical reflectivity (of their own and others' learning), and creativity. The significance of this research included the use and support of existing theory in both Adult Education and Human Resource Development. Further, this research represents the first of its kind in investigating informal learning in rehabilitative therapies, specifically Speech-Language Pathology. Peer professions such as Physical and Occupational Therapy may also benefit from this study's conclusions and recommendations, as these professionals work in similar medical contexts.
Show less - Date Issued
- 2008
- PURL
- http://purl.flvc.org/FAU/186323
- Subject Headings
- Audiology, Practice, Methodology, Speech therapy, Practice, Methodology, Interpersonal communication, Study and teaching
- Format
- Document (PDF)
- Title
- Predictive modeling of archaeological site location in Cuba.
- Creator
- Watson, April A., Dorothy F. Schmidt College of Arts and Letters, Department of Anthropology
- Abstract/Description
-
This work aimed at aiding academic and CRM professionals in archaeology by developing a predictive model of prehistoric sites on the southeastern coast of Cuba. The variables in this model were identified by previous archaeological research at Guantâanamo Bay Naval Station. Both GIS analysis and weights of evidence testing were conducted on the model. The results of the GIS and statistical analysis allowed for refinement of the model. Cuba is central to understanding the prehistoric...
Show moreThis work aimed at aiding academic and CRM professionals in archaeology by developing a predictive model of prehistoric sites on the southeastern coast of Cuba. The variables in this model were identified by previous archaeological research at Guantâanamo Bay Naval Station. Both GIS analysis and weights of evidence testing were conducted on the model. The results of the GIS and statistical analysis allowed for refinement of the model. Cuba is central to understanding the prehistoric settlement of the Caribbean. The model explored not only site occurrence and environmental correlations, but also looked at intersite correlations. It was determined that site occurrences are strongly linked to low elevation, proximity to other sites, south-facing areas, mangroves, and geologic formations. This model may add to the understanding of the prehistoric settling of Cuba, as well as the interactions between native groups.
Show less - Date Issued
- 2011
- PURL
- http://purl.flvc.org/FAU/3174309
- Subject Headings
- Geographic information systems, Archaeology, Methodology, Archaeology, Geographic information systems
- Format
- Document (PDF)
- Title
- Predicting hospital readmissions in patients with diabetes: the importance of diabetes education and other factors.
- Creator
- Asper, Darwin E., College of Education, Department of Educational Leadership and Research Methodology
- Abstract/Description
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The objective of this study was to determine whether 11 independent variables or combinations of variables help to predict a diabetes-related hospital readmission for patients with diabetes within 60 days from discharge. The variables were categorized into four main groups: (a) patient characteristics, (b) lifestyle, (c) biomarkers, and (d) disease management aspects. A convenience sample of 389 historical medical records of patients who were admitted to a rural hospital in northeastern North...
Show moreThe objective of this study was to determine whether 11 independent variables or combinations of variables help to predict a diabetes-related hospital readmission for patients with diabetes within 60 days from discharge. The variables were categorized into four main groups: (a) patient characteristics, (b) lifestyle, (c) biomarkers, and (d) disease management aspects. A convenience sample of 389 historical medical records of patients who were admitted to a rural hospital in northeastern North Carolina with a diagnosis of, or relating to, diabetes was studied. After comparing predictive discriminant analysis (PDA) and logistic regression (LR), PDA performed better and was chosen to analyze a convenience sample of patients admitted to the hospital for a diabetes-related diagnosis from January, 2004 to December, 2006. The best overall subset accurately classified 27 cases with six predictors that included (a) systolic blood pressure, (b) smoking status, (c) blood glucose range, (d) ethnicity, (e) diabetes education, and (f) diastolic blood pressure. In an effort to simplify the prediction process, the subsets of two predictors were examined. The results of the analysis returned four subsets of 2-predictor variable combinations that correctly classified cases for readmission. Each of the four subsets has two predictors that are statistically and practically significant for predicting readmissions for a diabetes-related problem within fewer than 60 days. These combinations are the predictor subsets of (a) smoking status and being treated by a specialist or non-specialist physician, (b) a religious affiliation or a lack thereof and smoking status, (c) gender and smoking status, and (d) smoking status and ethnicity.
Show less - Date Issued
- 2009
- PURL
- http://purl.flvc.org/FAU/221947
- Subject Headings
- Outcome assessment (Medical care), Methodology, Medical care, Evaluation, Health services accessibility, Management, Patient education
- Format
- Document (PDF)
- Title
- Toward a pragmatics of intent: cognitive approaches in creative and critical writing.
- Creator
- Wolfe, Lois., Dorothy F. Schmidt College of Arts and Letters, Department of Languages, Linguistics and Comparative Literature
- Abstract/Description
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Locus of an author poses questions of intentionality, how intention is discovered, expressed, hidden, revealed and interpreted. The purpose of the study is to find and apply productive interdisciplinary concepts in intentionality detection, decoding and evaluation in fictional texts. The investigation integrates traditions in literature, linguistics, cognitive science and creative writing, posing a pragmatics of intent that complements and complicates precepts in reader reception-based...
Show moreLocus of an author poses questions of intentionality, how intention is discovered, expressed, hidden, revealed and interpreted. The purpose of the study is to find and apply productive interdisciplinary concepts in intentionality detection, decoding and evaluation in fictional texts. The investigation integrates traditions in literature, linguistics, cognitive science and creative writing, posing a pragmatics of intent that complements and complicates precepts in reader reception-based constructivism. Basic to a vision of pragmatic strategies: 1) situating effect and affect in an embodied mind; 2) acknowledging mutual and/or oppositional intentionalities which an embodied author and embodied reader bring to the process of fictional communication; 3) accepting language as communication that requires cognitive translation of consensually-agreed upon symbols into private representations in an embodied mind; 4) assuming that an author's fictionalizing consciousness is more discernible w hen it is navigating tensions of selection, proportion, intervention and perspective. Perceptual and close reading of J.M. Coetzee's Foe yields descriptive problematics. Analytical readings in a neglected byway of I.A. Richards' New Criticism provide pragmatic cues for detecting and evaluating intentionalities in prose. Three cross-disciplinary strategies emerge to enhance perceptual and close readings of fictional texts: 1) awareness of priming effects in form and content; 2) identification of markedness patterns; and 3) perception of tensible connections in prosaic language and artistic devices., The study concludes that: reading in tensible awareness of author intentionality adds productively to critical analysis and argument; acknowledging positioned voices in texts supports ethical criticism and multicultural aesthetics; reading to apprehend perceptual units (image structures sensed through story) supports and contextualizes close reading of propositional units(discourse/language) . The formal element of perspective emerges as the most intensive locus of the reader's sense of integrated consciousness and management of effect in fiction. Perspective can create the most ergative construction of authorial perspective, i.e., one in which transitive energy appears equalized and the subject and patient / writer and reader positions in syntax can pivot.
Show less - Date Issued
- 2008
- PURL
- http://purl.flvc.org/FAU/165946
- Subject Headings
- Intentionality (Philosophy), Philosophy of mind, Attribution (Social psychology), Reportage literature (Authorship), Creative writing, Methodology
- Format
- Document (PDF)
- Title
- The application of the less is more hypothesis in foreign language learning.
- Creator
- Chin, Simone L., Charles E. Schmidt College of Science, Department of Psychology
- Abstract/Description
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This study tests Newports Less is More hypothesis with a language teaching experiment. Computerized French language lessons were presented to forty-two adults over two one-hour sessions. Learning trials were presented either in full sentences to resemble the adult learning environment, or in small increments that gradually increased to full sentences, resembling the steadily expanding processing capabilities of children. Trials were also presented randomly or ordered such that multiple...
Show moreThis study tests Newports Less is More hypothesis with a language teaching experiment. Computerized French language lessons were presented to forty-two adults over two one-hour sessions. Learning trials were presented either in full sentences to resemble the adult learning environment, or in small increments that gradually increased to full sentences, resembling the steadily expanding processing capabilities of children. Trials were also presented randomly or ordered such that multiple examples of the same objects and verbs were presented consecutively. Language proficiency tests were administered after the lessons. A 2 (Presentation: incremental or full sentence) x 2 (Order of presentation: blocked or random) mixed ANOVA was used to analyze the data. The incremental conditions outperformed the sentence conditions on all proficiency measures. There was no significant effect of the blocking manipulation. This outcome suggests that a teaching method based on Newport's Less is More hypothesis can be advantageous in learning a foreign language.
Show less - Date Issued
- 2009
- PURL
- http://purl.flvc.org/FAU/368254
- Subject Headings
- Second language acquisition, Methodology, Language and languages, Study and teaching, Cognitive grammar, Biolinguistics, Human information processing
- Format
- Document (PDF)
- Title
- The neural correlates of endogenously cued covert visuospatial attentional shifting in the cue-target interval: an electroencephalographic study.
- Creator
- Modestino, Edward Justin., Charles E. Schmidt College of Science, Center for Complex Systems and Brain Sciences
- Abstract/Description
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This study investigated electroencephalographic differences related to cue (central left- or right-directed arrows) in a covert endogenous visual spatial attention task patterned after that of Hopf and Mangun (2000). This was done with the intent of defining the timing of components in relation to cognitive processes within the cue-target interval. Multiple techniques were employed to do this. Event-related potentials (ERPs) were examined using Independent Component Analysis. This revealed a...
Show moreThis study investigated electroencephalographic differences related to cue (central left- or right-directed arrows) in a covert endogenous visual spatial attention task patterned after that of Hopf and Mangun (2000). This was done with the intent of defining the timing of components in relation to cognitive processes within the cue-target interval. Multiple techniques were employed to do this. Event-related potentials (ERPs) were examined using Independent Component Analysis. This revealed a significant N1, between 100:200 ms post-cue, greater contralateral to the cue. Difference wave ERPs, left minus right cue-locked data, divulged significant early directing attention negativity (EDAN) at 200:400 ms post-cue in the right posterior which reversed polarity in the left posterior. Temporal spectral evolution (TSE) analysis of the alpha band revealed three stages, (1) high bilateral alpha precue to 120 ms post-cue, (2) an event related desynchronization (ERD) from approximately 120 ms: 500 ms post-cue, and (3) an event related synchronization (ERS) rebound, 500: 900 ms post-cue, where alpha amplitude, a measure of activity, was highest contralateral to the ignored hemifield and lower contralateral to the attended hemifield. Using a combination of all of these components and scientific literature in this field, it is possible to plot out the time course of the cognitive events and their neural correlates.
Show less - Date Issued
- 2009
- PURL
- http://purl.flvc.org/FAU/369199
- Subject Headings
- Brain mapping, Neural networks (Neurobiology), Cognitive neuroscience, Recognition (Psychology), Cognition, Research, Methodology
- Format
- Document (PDF)
- Title
- A new method to achieve lithic use-wear discrimination using laser scanning confocal microscopy.
- Creator
- Farber, Elliott, Dorothy F. Schmidt College of Arts and Letters, Department of Anthropology
- Abstract/Description
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My study sought to acquire quantitative data from the surface of lithic tools and use that data to discriminate tools used on different contact materials. An experimental archaeological wear production method was conceived, whereby I and several volunteers produced wear on chert, heat-treated chert, and obsidian flakes by using those flakes on several contact materials. The flakes were then analyzed using a laser scanning confocal microscope, which recorded three-dimensional surface data from...
Show moreMy study sought to acquire quantitative data from the surface of lithic tools and use that data to discriminate tools used on different contact materials. An experimental archaeological wear production method was conceived, whereby I and several volunteers produced wear on chert, heat-treated chert, and obsidian flakes by using those flakes on several contact materials. The flakes were then analyzed using a laser scanning confocal microscope, which recorded three-dimensional surface data from each tool. The data was analyzed using cluster analysis to find the ideal combination of parameters which correctly discriminated the flakes based on use-wear data. After finding acceptable parameters which grouped flakes appropriately through cluster analysis, those groups were subjected to a discriminant analysis. Each analysis returned a p-value under .05, meaning that the clustering based on the parameters Sq and Sfd produced by the cluster analysis was not random, but indicative of these variables' ability to discriminate lithic use-wear. The major advantage of the approach developed in this study is that it can quantitatively discriminate use-wear produced by different contact materials on flakes with no a priori information at all.
Show less - Date Issued
- 2013
- PURL
- http://purl.flvc.org/fcla/dt/3362342
- Subject Headings
- Archaeology, Methodology, Archaeological surveying, Laser use in, Topographical surveying, Laser use in, Nanostructured materials, Tools, Prehistoric, Analysis
- Format
- Document (PDF)