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Pages
- Title
- A study of Caenorhabditis elegans tissue inhibitor of metalloproteinases.
- Creator
- Paul, Tamara., Florida Atlantic University, Brew, Keith
- Abstract/Description
-
Tissue Inhibitors of Metalloproteinases (TIMPs) are produced by a wide variety of cell types. Similar to matrixins, the expression of TIMPs in the tissue is also controlled during tissue remodeling and physiological conditions to maintain a balance in the metabolism of extracellular matrix. Disruption of this balance can result in diseases associated with uncontrolled turnover of matrix, such as arthritis, cancer, and cardiovascular disease. Some of the biological processes TIMPs participate...
Show moreTissue Inhibitors of Metalloproteinases (TIMPs) are produced by a wide variety of cell types. Similar to matrixins, the expression of TIMPs in the tissue is also controlled during tissue remodeling and physiological conditions to maintain a balance in the metabolism of extracellular matrix. Disruption of this balance can result in diseases associated with uncontrolled turnover of matrix, such as arthritis, cancer, and cardiovascular disease. Some of the biological processes TIMPs participate in include: regulation of cell morphology and organ morphogenesis, inhibition of angiogenesis, steroidogenesis, and tissue remodeling. One major function of TIMPs is inhibition of Matrix Metaloproteinase (MMPs). This project used bioinformatic techniques to identify two Caenorhabditis elegans TIMP cDNA cloned by BLAST searching of EST database. These TIMP cDNA were amplified, cloned and expressed, proteins were purified. Kinetic studies were carried out to evaluate the inhibitory activities against various MMPs and TACE. This research project will provide some insight on the function of C. elegans TIMPs.
Show less - Date Issued
- 2006
- PURL
- http://purl.flvc.org/fcla/dt/13414
- Subject Headings
- Endopeptidases--Inhibitors, Proteolytic enzymes, Extracellular matrix proteins, Metalloproteinases--Inhibitors
- Format
- Document (PDF)
- Title
- A study of bioeffluents in a college classroom.
- Creator
- Wang, Tsen C., Harbor Branch Oceanographic Institute
- Date Issued
- 1975
- PURL
- http://purl.flvc.org/fau/fd/FA00007050
- Subject Headings
- Pollutants, Indoor air quality, Gases, Vapors
- Format
- Document (PDF)
- Title
- A Study of a Curriculum to be Conducted Mainly by Television for Secondary School Children Living in American Samoa.
- Creator
- Steinbaugh, Byron Frew, Howard, Homer, Florida Atlantic University
- Abstract/Description
-
In 1900 Commander Benjamin F. Tilley, then in administrative charge of the Samoan Islands for the United States Navy, found a greater degree of literacy among the Samoan people in their own language than among Americans in the United States in the English language. The missionaries had pioneered in furthering education in Samoa for the main purpose of training native pastors and they made great numbers of the people highly literate in their own tongue. However, the naval administration, from...
Show moreIn 1900 Commander Benjamin F. Tilley, then in administrative charge of the Samoan Islands for the United States Navy, found a greater degree of literacy among the Samoan people in their own language than among Americans in the United States in the English language. The missionaries had pioneered in furthering education in Samoa for the main purpose of training native pastors and they made great numbers of the people highly literate in their own tongue. However, the naval administration, from the beginning of their rule, adopted a policy of establishing a secular school system for the people. In addition to the work of the missionaries , the naval administrator, on July 6, 1901, requested that the Navy Department allot money for the purpose of establishing a school near the naval station. This was to mark the start of many appeals for federal assistance to establish a complete range of public schools in American Samoa.
Show less - Date Issued
- 1966
- PURL
- http://purl.flvc.org/fau/fd/FA00000645
- Subject Headings
- Education--Curricula--American Samoa, Television in secondary education--American Samoa, Education, Secondary--American Samoa
- Format
- Document (PDF)
- Title
- A Study in Implementing Autonomous Video Surveillance Systems Based on Optical Flow Concept.
- Creator
- Fonseca, Alvaro A., Zhuang, Hanqi, Marques, Oge, Florida Atlantic University
- Abstract/Description
-
Autonomous video surveillance systems are usually built with several functional blocks such as motion detection, foreground and background separation, object tracking, depth estimation, feature extraction and behavioral analysis of tracked objects. Each of those blocks is usually designed with different techniques and algorithms, which may need significant computational and hardware resources. In this thesis we present a surveillance system based on an optical flow concept, as a main unit on...
Show moreAutonomous video surveillance systems are usually built with several functional blocks such as motion detection, foreground and background separation, object tracking, depth estimation, feature extraction and behavioral analysis of tracked objects. Each of those blocks is usually designed with different techniques and algorithms, which may need significant computational and hardware resources. In this thesis we present a surveillance system based on an optical flow concept, as a main unit on which other functional blocks depend. Optical flow limitations, capabilities and possible problem solutions are discussed in this thesis. Moreover, performance evaluation of various methods in handling occlusions, rigid and non-rigid object classification, segmentation and tracking is provided for a variety of video sequences under different ambient conditions. Finally, processing time is measured with software that shows an optical flow hardware block can improve system performance and increase scalability while reducing the processing time by more than fifty percent.
Show less - Date Issued
- 2007
- PURL
- http://purl.flvc.org/fau/fd/FA00012516
- Subject Headings
- Electronic surveillance, Optical pattern recognition, Computer vision, Optical flow--Image analysis
- Format
- Document (PDF)
- Title
- A student posing next to a Paper Clip sculpture on Boca Raton campus.
- Creator
- Florida Atlantic University
- Abstract/Description
-
A student posing next to a paper clip sculpture. Florida Atlantic University, Boca Raton campus. Dates are approximate.
- Date Issued
- 1980 - 1990
- PURL
- http://purl.flvc.org/fau/fd/faua0000147
- Subject Headings
- Florida Atlantic University -- History, Florida Atlantic University -- Students, Florida Atlantic University -- Photographs, Florida Atlantic University -- Archives
- Format
- Image (JPEG)
- Title
- A structural and thermodynamic comparison of substrate interactions and catalysis by family 6 glycosyltransferases from Bacteroides ovatus, Parachlamydia acanthamoebae, and Bos taurus.
- Creator
- Stinson, Brittany, Brew, Keith, Florida Atlantic University, Charles E. Schmidt College of Science, Department of Biological Sciences
- Abstract/Description
-
Family 6 Glycosyltransferases (GT6s) are involved in the biosynthesis of complex glycans and can be found in all vertebrates, cyanophages, and some bacteria and unicellular eukaryotes. Understanding variations within family 6 GTs is important because of the roles of their products in cellular recognition, intercellular interactions, pathogenicity, and immunity and is likewise important for understanding the evolution of GTs. PaGT6 (from Parchlamydia acanthamoebae) and α3GT (from Bos taurus)...
Show moreFamily 6 Glycosyltransferases (GT6s) are involved in the biosynthesis of complex glycans and can be found in all vertebrates, cyanophages, and some bacteria and unicellular eukaryotes. Understanding variations within family 6 GTs is important because of the roles of their products in cellular recognition, intercellular interactions, pathogenicity, and immunity and is likewise important for understanding the evolution of GTs. PaGT6 (from Parchlamydia acanthamoebae) and α3GT (from Bos taurus) both require a divalent metal ion for catalysis which binds to a DXD motif. In BoGT6a from Bacteroides ovatus a NXN motif replaces DXD, and activity is metal-independent. However, mutating the NXN motif in BoGT6a to DXD did not introduce metal-dependency, indicating that metal-dependency is linked to additional differences. Calorimetric studies have shown that the presence of a divalent metal ion enhances UDP and donor substrate binding to PaGT6 and causes an increase in the entropy of the interaction. Protein modelling of PaGT6 has revealed that the presence of Mn2+ allows a hydrogen bond to form between Asp 97 and UDP-GalNAc, causing the donor substrate to bend and form hydrogen bonds with His 119, Asn 229, Lys 228, and Arg 234. These interactions do not occur in the absence of Mn2+. Investigation of acceptor substrate binding revealed that the presence of UDP enhances acceptor substrate binding to BoGT6a and PaGT6. Calorimetric titrations of BoGT6a with 2-fucosyllactose in the absence and presence of UDP showed that UDP increases the affinity of 2-fucosyllactose 16-fold with little effect on ΔH. Measurements of ΔCp for 2-fucosyllactose binding indicate that there is not a hydrophobic effect for the binding of 2-fucosyllactose. The preferred acceptor substrate for the bovine and Bacteroides GT6 has a β-1,4 linked galactose, but P. acanthamoebae GT6 prefers an acceptor substrate with a β-1,3 linked galactose. The N-terminus of the catalytic domain of bacterial GT6s is truncated by 47 residues relative to the catalytic domain of bovine α3GT. Removal of this region from α3GT results in an unfolded protein, indicating that although this region is not directly involved in substrate binding, it forms interactions necessary for the stability of the catalytic domain.
Show less - Date Issued
- 2018
- PURL
- http://purl.flvc.org/fau/fd/FA00013047
- Subject Headings
- Glycosyltransferases, Bacteroides, Chlamydiales, Acanthamoeba, Bos taurus, Cattle
- Format
- Document (PDF)
- Title
- A stress analysis of the submersible tracking & communications mast attached to sea diver.
- Creator
- Bernard, Steven
- Date Issued
- 1977-03-17
- PURL
- http://purl.flvc.org/fcla/dt/3358606
- Subject Headings
- Submersibles, Submersibles--Design and construction, Oceanographic submersibles
- Format
- Document (PDF)
- Title
- A strategy for sharing your research: Make your work open access.
- Creator
- Ress, Sunghae
- Abstract/Description
-
Presented at the 2017 International Open Access Week
- PURL
- http://purl.flvc.org/fau/fd/FAUIR000415
- Subject Headings
- Open access publishing, Open access
- Format
- Document (PDF)
- Title
- A Strategic Plan for the Race to Excellence 2015-2025.
- Creator
- Florida Atlantic University
- Date Issued
- 2015-03-24
- PURL
- http://purl.flvc.org/fau/fd/FAUAD00001
- Format
- Document (PDF)
- Title
- A Statistical Analysis of the U.S. News and World Report's Honor Roll List of Best Hospitals Via County Mortality Rates.
- Creator
- Evans, Brian, McGovern, Warren W., Harriet L. Wilkes Honors College
- Abstract/Description
-
With the widespread use of the internet, information regarding medical facilities and practices has never been easier to obtain. This convenience may often prove beneficial, but using the internet to research topics regarding one's own health creates a potential for risks. This research addresses these concerns by studying the annual Honor Roll list of hospitals, a listing published each year by the U.S. News and World Report that ranks the best medical facilities in the country. To...
Show moreWith the widespread use of the internet, information regarding medical facilities and practices has never been easier to obtain. This convenience may often prove beneficial, but using the internet to research topics regarding one's own health creates a potential for risks. This research addresses these concerns by studying the annual Honor Roll list of hospitals, a listing published each year by the U.S. News and World Report that ranks the best medical facilities in the country. To accomplish this, we aimed to analyze the relationship between the hospitals listed on the Honor Roll and the mortality rates of the counties in which each hospital is located. Upon completion of this research, we were unable to find a significant difference between mortality rates of counties with Honor Roll hospitals and those without.
Show less - Date Issued
- 2016
- PURL
- http://purl.flvc.org/fau/fd/FA00003668
- Format
- Document (PDF)
- Title
- A STATEWIDE ANALYSIS OF THE SOCIAL DETERMINANTS OF OPIOID-RELATED DEATHS IN OLDER ADULTS.
- Creator
- Suriaga, Armiel, Bryan, Valerie C., Florida Atlantic University, Christine E. Lynn College of Nursing, Christine E. Lynn College of Nursing
- Abstract/Description
-
Background: Opioid-related deaths remain a significant public health problem in the United States. Opioids cause approximately 75% of all drug-related deaths. Since 1999, nearly half a million Americans have died from opioid overdoses. In 2018, 9,290 people > 55 years old died from opioid overdoses in the United States. In Florida, more than 1,000 older adults died from opioids (as a cause of death) from 2014-2018. However, there is a dearth of research about the manner of deaths of older...
Show moreBackground: Opioid-related deaths remain a significant public health problem in the United States. Opioids cause approximately 75% of all drug-related deaths. Since 1999, nearly half a million Americans have died from opioid overdoses. In 2018, 9,290 people > 55 years old died from opioid overdoses in the United States. In Florida, more than 1,000 older adults died from opioids (as a cause of death) from 2014-2018. However, there is a dearth of research about the manner of deaths of older adults who used, misused, or abused opioids. Methods: This secondary analysis utilized data from the Florida Drug and Law Enforcement (FDLE) agency between 2014 - 2018. A generalized linear model with a normal probability distribution was used to examine which social determinants or factors such as race, income, education level, percentage of people in poverty, and population density predicted opioid death rate in Florida. Chi-square statistics were used to determine the association between gender, race, and opioid-related deaths (ORD), and the relationship of the manner of death to the opioid drugs involved. The trend of opioid death rate was also analyzed by Florida county and through the data years 2014 to 2018.
Show less - Date Issued
- 2021
- PURL
- http://purl.flvc.org/fau/fd/FA00013683
- Subject Headings
- Opioids, Older people, Death
- Format
- Document (PDF)
- Title
- A standard reference diet for crustacean nutrition research. VI. Response of postlarval stages of the Caribbean king crab Mithrax spinosissimus and the spiny lobster Panulirus argus.
- Creator
- Lellis, W. A., Harbor Branch Oceanographic Institute
- Date Issued
- 1992
- PURL
- http://purl.flvc.org/FCLA/DT/3342301
- Subject Headings
- Crustacea--Nutrition, Panulirus argus, Caribbean spiny lobster, King crabs, Diet, Nutrition--Research
- Format
- Document (PDF)
- Title
- A SPIRITUAL FRAMEWORK OF ORGANIC ONENESS: THE ECO-THEOLOGICAL SHIFT TOWARDS A COLLECTIVE ECOLOGICAL CONSCIOUSNESS.
- Creator
- Durand, Kjirsten, Banchetti, Marina P., Department of Philosophy, Dorothy F. Schmidt College of Arts and Letters
- Abstract/Description
-
Earth’s environment has been undergoing unprecedented rates of degradation during the Anthropocene paradigm. Current projections for the near future show climate change producing grim outcomes for most habitable parts of the world. This thesis defends the argument that in order to adequately address the state of the environment, humanity must experience a shift in collective consciousness away from the current philosophical paradigm, and instead adopt a paradigm that enables a common mindset...
Show moreEarth’s environment has been undergoing unprecedented rates of degradation during the Anthropocene paradigm. Current projections for the near future show climate change producing grim outcomes for most habitable parts of the world. This thesis defends the argument that in order to adequately address the state of the environment, humanity must experience a shift in collective consciousness away from the current philosophical paradigm, and instead adopt a paradigm that enables a common mindset regarding the place of humans within the natural environment. Various forms of spiritual ecology are explored: deep ecology, biblical eco-theology, and eco-feminist theology. These positions are explored in order to introduce a framework necessary to achieve the collective shift in consciousness required to address environmental issues: a Spiritual Framework of Organic Oneness, which includes components of spiritual ecology and earth-centered religious traditions.
Show less - Date Issued
- 2017
- PURL
- http://purl.flvc.org/fau/fd/FAUIR000229
- Format
- Document (PDF)
- Title
- A speech delivered in the Senate of New-York on the third and fourth of February, 1832 : on the resolution against renewing the charter of the Bank of the United States.
- Creator
- Maynard, William Hale 1787 or 1788-1832, Packard, Hoffman & White
- Abstract/Description
-
By William H. Maynard. Caption title: Mr. Maynard's speech. FAU copy edges trimmed to 21 cm.
- PURL
- http://purl.flvc.org/fau/fd/fauwsb11f11
- Subject Headings
- Bank of the United States (1816-1836), Banks and banking -- Government policy -- United States, Banks and banking, Central -- United States, Jackson, Andrew -- 1767-1845, Legislative addresses -- 1832, Speeches, addresses, etc., American -- 19th century, United States -- Politics and government -- 1829-1837
- Format
- E-book
- Title
- A speech delivered by George Wood, Esq., before a committee of the friends of Daniel Webster : at Constitution Hall, New-York, on Tuesday evening, 4th May, 1852.
- Creator
- Wood, George 1789-1860, Whig Party (U.S.)
- Abstract/Description
-
Delivered at a meeting to consider Webster's candidacy for the Presidency. FAU copy trimmed to 23 cm; side stitched with cord.
- PURL
- http://purl.flvc.org/fau/fd/fauwsb16f3
- Subject Headings
- Presidents -- Nomination, Presidents -- United States -- Election -- 1852, Presidents -- United States -- Nomination, Speeches, addresses, etc., American -- 19th century, United States -- Politics and government -- 1849-1853, Webster, Daniel -- 1782-1852, Whig Party (U.S.)
- Format
- E-book
- Title
- A specialized ROV for cleaning groundwater recharge basins.
- Creator
- Kocak, D. M., Neely, J. W., Holt, John K., Miyake, Michio, Harbor Branch Oceanographic Institute
- Date Issued
- 1999
- PURL
- http://purl.flvc.org/FCLA/DT/3183713
- Subject Headings
- Automobiles --Design and construction, Engineering design, Propellers, Experimental automobiles, Remote submersibles
- Format
- Document (PDF)
- Title
- A Soviet city and its people.
- Creator
- Garelik, Joseph
- Date Issued
- 1950
- PURL
- http://purl.flvc.org/fcla/DT/1930514
- Subject Headings
- Ukraine --Social conditions., Dniprodzerzhyns’k (Ukraine).
- Format
- Document (PDF)
- Title
- A solemn protest against the late declaration of war : in a discourse, delivered on the next Lord's day after the tidings of it were received.
- Creator
- Osgood, David 1747-1822, Hilliard and Metcalf
- Abstract/Description
-
By David Osgood, D.D., pastor of the Church in Medford. Caption title: A solemn protest.
- PURL
- http://purl.flvc.org/fau/fd/fauwsb9f12
- Subject Headings
- Bible -- Chronicles, 2nd, XIII, 12 -- Sermons, Sermons -- New Hampshire -- Medford -- 1812, United States -- History -- War of 1812 -- Sermons, United States -- Politics and government -- 1812-1815 -- Sermons, War of 1812
- Format
- E-book
- Title
- A Socialist ritual.
- Date Issued
- 1989
- PURL
- http://purl.flvc.org/FCLA/DT/3358293
- Subject Headings
- Socialism -- Anecdotes, facetiae, satire, etc.
- Format
- Document (PDF)
- Title
- A Social-Emotional Leadership Framework for School Counselors.
- Creator
- Bowers, Hannah, Lemberger-Truelove, Matthew E., Brigman, Greg
- Date Issued
- 2017-01-07
- PURL
- http://purl.flvc.org/fau/flvc_fau_islandoraimporter_10.1177_2156759X18773004_1638554912
- Format
- Document (PDF)
