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Pages
- Title
- Low frequency nearshore current fluctuations on Florida’s central east coast.
- Creator
- Zweck, O. V., Hale, D. A., Harbor Branch Oceanographic Institute
- Date Issued
- 1979
- PURL
- http://purl.flvc.org/FCLA/DT/3183150
- Subject Headings
- Water currents, Tidal currents, Ocean waves--Analysis
- Format
- Document (PDF)
- Title
- Dos gegnbete bukh.
- Creator
- Zunke, Alvaro
- Date Issued
- 1938
- PURL
- http://purl.flvc.org/fau/2866774
- Subject Headings
- Children's literature, Yiddish
- Format
- Document (PDF)
- Title
- L is for labor: a glossary of labor terms.
- Creator
- Zugsmith, Leane
- Date Issued
- 1937
- PURL
- http://purl.flvc.org/fcla/DT/221839
- Subject Headings
- Labor movement --Dictionaries.
- Format
- Document (PDF)
- Title
- The construction of metal-organic hybrid materials based on benzophenone-4,4'-dicarboxylic acid.
- Creator
- Zribi, Dan, Torres, Melissa, De Lill, Daniel T.
- Date Issued
- 2013-04-05
- PURL
- http://purl.flvc.org/fcla/dt/3361243
- Subject Headings
- Dicarboxylic acids, Benzophenones, Lanthanides, Transition metals
- Format
- Document (PDF)
- Title
- Thermodynamic Basis of Selectivity in the Interactions of Tissue Inhibitors of Metalloproteinases N-domains with Matrix Metalloproteinases-1, -3, and -14.
- Creator
- Zou, Haiyin, Wu, Ying, Brew, Keith
- Date Issued
- 2016-05
- PURL
- http://purl.flvc.org/fau/flvc_fau_islandoraimporter_10.1074_jbc.M116.720250_1638376717
- Format
- Document (PDF)
- Title
- Synthesis of Complex Polycyclic Scaffolds Incorporating α-Amino Esters.
- Creator
- Zorc, Stephen A., Samanta, Shyam S., Roche, Stéphane P., Charles E. Schmidt College of Science
- Abstract/Description
-
In order to keep up with the high demand for biologically active molecules, chemists devised several synthetic strategies to access novel chemical spaces. The two main strategies to construct new scaffolds are to revisit underexploited or forgotten reactions or to devise new transformations. We are exploring a unique and underexploited reaction, the Himbert–Henn cycloaddition, to produce complex molecular scaffolds in a single step (strategy 1). In a second novel approach, we are modifying...
Show moreIn order to keep up with the high demand for biologically active molecules, chemists devised several synthetic strategies to access novel chemical spaces. The two main strategies to construct new scaffolds are to revisit underexploited or forgotten reactions or to devise new transformations. We are exploring a unique and underexploited reaction, the Himbert–Henn cycloaddition, to produce complex molecular scaffolds in a single step (strategy 1). In a second novel approach, we are modifying the Hantzsch 4-component reaction (4CR) by incorporating an α-amino ester residue to construct new molecules (strategy 2). Both of these reactions have great potential to synthesize novel and chiral molecules from proteinogenic α-amino esters. These unprecedented and complex polycyclic molecules have potential application in medicinal chemistry and natural product synthesis. 4-aza-podophyllotoxins obtained by the Hantzsch-4CR have been proven to be potent as anti-leukemia, anti-colon cancer, and vascular disrupting agents (with nanomolar activity).
Show less - Date Issued
- 2015
- PURL
- http://purl.flvc.org/fau/fd/FA00005218
- Subject Headings
- College students --Research --United States.
- Format
- Document (PDF)
- Title
- Correlation between Specific Carcinogens and Mitotic Defects in Uterine Cancer.
- Creator
- Zlotcavitch, Leonid, Quintyne, Nicholas, Harriet L. Wilkes Honors College, Florida Atlantic University
- Abstract/Description
-
The development of uterine cancer and its progression can be linked to external elements such as carcinogens, natural hormones and chemotherapeutic drugs. The goal of this project was to investigate the possible correlation between exposure to specific chemical and an increase of mitotic defects. These defects manifest themselves as lagging chromosomes, multipolar spindles, and anaphase bridges. Using the uterine cancer cell line MES-SA as a model, we established a baseline for the mitotic...
Show moreThe development of uterine cancer and its progression can be linked to external elements such as carcinogens, natural hormones and chemotherapeutic drugs. The goal of this project was to investigate the possible correlation between exposure to specific chemical and an increase of mitotic defects. These defects manifest themselves as lagging chromosomes, multipolar spindles, and anaphase bridges. Using the uterine cancer cell line MES-SA as a model, we established a baseline for the mitotic defects in the absence and presence of various chemicals using γ-tubulin and DAPI-immune stained fixed cells. The cells were treated with varying concentrations of Vinyl Chloride, β-estradiol, Fluvestrant, and were examined using Immunofluorescent microscopy. We found that an exposure to Vinyl Chloride, β-estradiol and Fulvestrant have increased the number of mitotic defects in this cell line.
Show less - Date Issued
- 2011
- PURL
- http://purl.flvc.org/fau/fd/FA00003611_0
- Format
- Document (PDF)
- Title
- Yasir Arafat and the PLO one month since Hebron: An assessment of PLO compliance with the Hebron Accord January 15 – February 15, 1997.
- Creator
- Zionist Organization of America
- Abstract/Description
-
This item is part of the Political & Rights Issues & Social Movements (PRISM) digital collection, a collaborative initiative between Florida Atlantic University and University of Central Florida in the Publication of Archival, Library & Museum Materials (PALMM).
- Date Issued
- 1997
- PURL
- http://purl.flvc.org/fau/fd/FA00002715
- Subject Headings
- Arab-Israeli conflict -- 1993 -- Peace
- Format
- Document (PDF)
- Title
- Zwölf Tage in Deutschland.
- Creator
- Zinovyev, Grigory Yevseyevich
- Date Issued
- 1920
- PURL
- http://purl.flvc.org/FCLA/DT/3351420
- Subject Headings
- Socialism -- Germany
- Format
- Document (PDF)
- Title
- The British Commonwealth in the post-war world.
- Creator
- Zimmern, Alfred Eckhard, Sir
- Date Issued
- 1926
- PURL
- http://purl.flvc.org/FCLA/DT/2796218
- Subject Headings
- Reconstruction (1914-1939)
- Format
- Document (PDF)
- Title
- Transplanting and survival of the seagrass Halodule wrightii under controlled conditions.
- Creator
- Zimmermann, Carl F., French, T. D., Montgomery, John R., Harbor Branch Oceanographic Institute
- Date Issued
- 1981
- PURL
- http://purl.flvc.org/FCLA/DT/3340747
- Subject Headings
- Seagrasses, Seagrass restoration, Naphthaleneacetic acid, Transplanting (Plant culture)
- Format
- Document (PDF)
- Title
- A comparison of ceramic cup and Teflon in situ samplers for nutrient pore water determinations.
- Creator
- Zimmermann, Carl F., Price, Mary T., Montgomery, John R., Harbor Branch Oceanographic Institute
- Date Issued
- 1978
- PURL
- http://purl.flvc.org/FCLA/DT/3174478
- Subject Headings
- Estuaries, Estuarine sediments, Nutrient pollution of water, Water --Sampling, Pore water
- Format
- Document (PDF)
- Title
- Nitrogen and phosphorus uptakeand release by the blue-green alga Microcoleus lyngbyaceus.
- Creator
- Zimmermann, Carl F., Harbor Branch Oceanographic Institute
- Date Issued
- 1988
- PURL
- http://purl.flvc.org/fau/fd/FA00007188
- Subject Headings
- Indian River (Fla. : Lagoon), Blue-green algae, Cyanobacteria, Microcoleus, Nitrogen, Phosphorus
- Format
- Document (PDF)
- Title
- Effects of a decomposing drift algal mat on sediment pore water nutrient concentrations in a Florida seagrass bed.
- Creator
- Zimmermann, Carl F., Montgomery, John R., Harbor Branch Oceanographic Institute
- Date Issued
- 1984
- PURL
- http://purl.flvc.org/FCLA/DT/3350848
- Subject Headings
- Seagrasses, Pore water --Florida --Indian River, Algae --Ecology, Sediment control, Ammonium, Phosphate deposits
- Format
- Document (PDF)
- Title
- Variability of dissolved reactive phosphate flux rates in nearshore estuarine sediments: Effects of groundwater flow.
- Creator
- Zimmermann, Carl F., Montgomery, John R., Carlson, Paul R., Harbor Branch Oceanographic Institute
- PURL
- http://purl.flvc.org/FCLA/DT/3174856
- Subject Headings
- Estuarine sediments, Phosphates, Groundwater flow
- Format
- Document (PDF)
- Title
- Operation, methods, and quality control of Technicon AutoAnalyzer II Systems for nutrient determinations in seawater.
- Creator
- Zimmermann, Carl F., Price, Mary T., Montgomery, John R.
- Date Issued
- 1977-02
- PURL
- http://purl.flvc.org/fcla/dt/3358479
- Subject Headings
- Estuaries, Micronutrients, Seawater--Analysis
- Format
- Document (PDF)
- Title
- Herbivory and detritivory among gammaridean amphipods from a Florida seagrass community.
- Creator
- Zimmerman, R., Gibson, R. A., Harrington, J., Harbor Branch Oceanographic Institute
- Date Issued
- 1979
- PURL
- http://purl.flvc.org/FCLA/DT/3176695
- Subject Headings
- Amphipoda, Amphipods, Detritus, Amphipoda--Florida
- Format
- Document (PDF)
- Title
- Evaluating the DRY motif and its effects on ligand binding at the µ-Opioid Receptor.
- Creator
- Zimmerman, Frank, Bohn, Laura, Schmid, Cullen, Harriet L. Wilkes Honors College
- Abstract/Description
-
Opioids are considered the most efficacious drugs for management of moderate to severe pain, yet their use clinically is often restricted due to the onset of adverse side-effects. Drugs in this class produce most of their physiological effects (analgesia, nausea, vomiting) through activation of the μ-opioid receptor; however, an increasing number of studies have demonstrated that opioids can activate distinct downstream responses, a phenomenon termed functional selectivity. This project...
Show moreOpioids are considered the most efficacious drugs for management of moderate to severe pain, yet their use clinically is often restricted due to the onset of adverse side-effects. Drugs in this class produce most of their physiological effects (analgesia, nausea, vomiting) through activation of the μ-opioid receptor; however, an increasing number of studies have demonstrated that opioids can activate distinct downstream responses, a phenomenon termed functional selectivity. This project attempts to determine the amino acid residues involved in the activation of the μ-opioid receptor and the role they play in the binding of ligands to the receptor. The highly conserved DRY motif (aspartic acid-arginine-tyrosine) found commonly in GPCRs was mutated via site directed mutagenesis, aspartic acid-164 to alanine (A), glutamic acid (E), and arginine (R) and G-protein coupling and competition binding assays were performed to test whether ligand affinity and activity differed in the mutant receptors compared to the wild-type.
Show less - Date Issued
- 2016
- PURL
- http://purl.flvc.org/fau/fd/FA00003698
- Format
- Document (PDF)
- Title
- Utopias Imagined and Real: The Communities of George Rapp and Robert Owen in Relation to the Utopias Conceived by Plato and Sir Thomas More.
- Creator
- Zimmer, Rosina P., Keaton, Kenneth, Graduate College
- Date Issued
- 2011-04-08
- PURL
- http://purl.flvc.org/fcla/dt/3172443
- Subject Headings
- Plato, More, Thomas, Sir, Saint, 1478-1535, Utopias
- Format
- Document (PDF)
- Title
- The dying peace.
- Creator
- Zilliacus, K., Laski, Harold Joseph
- Date Issued
- 1933
- PURL
- http://purl.flvc.org/FCLA/DT/2796517
- Subject Headings
- Peace.
- Format
- Document (PDF)