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FAU Climate Change Initiative Priority Theme: Research, Engineering, and Adaption to a Change Climate
Title
FAU Climate Change Initiative Priority Theme: Research, Engineering, and Adaption to a Change Climate.
Creator
Berry, Leonard, Koch, Marguerite, Center for Environmental Studies, Benscoter, Brian, Comas, Xavier, Devlin, Donna, Fadiman, Maria, Gerstein, E., Herzing, Denise L., Hindle, Tobin, Milton, Sarah L., Oleinik, Anton E., Proffitt, C. Edward, Restrepo, Jorge I., Root, Tara L., Wyneken, Jeanette, Xie, Zhixiao, Zhang, Xing-Hai, Esnard, Ann-Margaret, Mitsova, Diana, Murley, J., Vos, J., Escaleras, Monica, Mehallis, M., Shaw, Eric H., Hardman, Guillermo [John], Lambert, Julie, Thomas, G., Arockiasamy, Madasamy, Bloetscher, Frederick, Carvalho, G., Dhanak, Manhar R., Frisk, George V., Kaisar, Evangelos I., Kalva, Hari, Meeroff, Daniel E., Rodriguez, Jarice, Scarlatos, Panagiotis (Pete) D., Shankar, Ravi, Teegavarapu, Ramesh, Brown, Clifford T., McAfee, Francis, Widener, Patricia, Dalgleish, Fraser R., Hanisak, M. Dennis, McMulloch, S., O'Corry-Crowe, Gregory, Pomponi, Shirley A., Reed, John K., Scarpa, John, Voss, Joshua, Heimlich, Barry N., Alvarez, R., Jolley, J., Edwards, A., Charles E. Schmidt College of Science, Harbor Branch Oceanographic Institute, College of Business, Dorothy F. Schmidt College of Arts and Letters, College of Education, College of Engineering and Computer Science
Date Issued
2010
PURL
http://purl.flvc.org/fau/fd/FA00003457
Format
Citation
A cGMP-dependent protein kinase (PKG) controls synaptic transmission tolerance to acute oxidative stress at the Drosophila larval neuromuscular junction
Title
A cGMP-dependent protein kinase (PKG) controls synaptic transmission tolerance to acute oxidative stress at the Drosophila larval neuromuscular junction.
Creator
Caplan, Stacee Lee, Milton, Sarah L., Dawson-Scully, Ken
Date Issued
2013-02-01
PURL
http://purl.flvc.org/fau/flvc_fau_islandoraimporter_10.1152_jn.00784.2011_1644861569
Format
Document (PDF)
Pharmacological protection of retinal pigmented epithelial cells by sulindac involves PPAR-α
Title
Pharmacological protection of retinal pigmented epithelial cells by sulindac involves PPAR-α.
Creator
Sur, Arunodoy, Kesaraju, Shailaja, Prentice, Howard, Ayyanathan, Kasirajan, Baronas-Lowell, Diane, Zhu, Danhong, Hinton, David R., Blanks, Janet, Weissbach, Herbert
Date Issued
2014-11-10
PURL
http://purl.flvc.org/fau/flvc_fau_islandoraimporter_10.1073_pnas.1419576111_1631807081
Format
Citation
Characteristics of mangrove swamps managed for mosquito control in eastern Florida, USA
Title
Characteristics of mangrove swamps managed for mosquito control in eastern Florida, USA.
Creator
Middleton, B, Devlin, D, Proffitt, E, McKee, K, Foster Getini, K
Date Issued
2008-11-19
PURL
http://purl.flvc.org/fau/flvc_fau_islandoraimporter_10.3354_meps07683_1644953107
Format
Document (PDF)
Perspectives on mosquito impoundments in eastern Florida, USA: Reply to Rey et al. (2009)
Title
Perspectives on mosquito impoundments in eastern Florida, USA: Reply to Rey et al. (2009).
Creator
McKee, KL, Middleton, BA, Proffitt, CE, Devlin, DJ
Date Issued
2009-09-04
PURL
http://purl.flvc.org/fau/flvc_fau_islandoraimporter_10.3354_meps08257_1645024447
Format
Document (PDF)
The Potential Therapeutic Effects of Low-Dose Ionizing Radiation in Alzheimer's Disease
Title
The Potential Therapeutic Effects of Low-Dose Ionizing Radiation in Alzheimer's Disease.
Creator
Joubin Jebelli, Michael C. Hamper, Danielle Van Quelef, Davian Caraballo, James Hartmann, James Kumi-Diaka
Abstract/Description
Dementia is an umbrella term used to describe a loss of cognitive function which results in the interference of an individual's daily life and activities. The most common form of dementia is Alzheimer's disease. Alzheimer’s is classified as a progressive, debilitating neurodegenerative disease that results in disturbances to a patient’s higher executive function, memory, language, and visuospatial orientation. Despite extensive research on Alzheimer’s dementia, including both available and...
Show moreDementia is an umbrella term used to describe a loss of cognitive function which results in the interference of an individual's daily life and activities. The most common form of dementia is Alzheimer's disease. Alzheimer’s is classified as a progressive, debilitating neurodegenerative disease that results in disturbances to a patient’s higher executive function, memory, language, and visuospatial orientation. Despite extensive research on Alzheimer’s dementia, including both available and potential therapeutic modalities, this neurodegenerative disease is incurable and will continue to pose a major public health concern. Current treatment options for Alzheimer’s focus on symptom management and/or delaying the progression of the disease. Therefore, new treatment strategies must be developed to combat such a deadly disease. One field of medicine that has garnered significant interest from researchers to potentially treat Alzheimer’s is lowdose ionizing radiation. Various reports suggest that the brain’s exposure to low doses of ionizing radiation may serve as a therapeutic modality for combating neurodegenerative diseases, including Alzheimer’s dementia. This article serves as a review of the current available treatments for Alzheimer’s disease and discusses recent studies that provide evidence for the potential use of low-dose ionizing radiation as a therapeutic in the treatment of Alzheimer’s disease.
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Date Issued
2022
PURL
http://purl.flvc.org/fau/fd/FAUIR000508
Format
Document (PDF)
Mechanisms That Generate Resource Pulses in a Fluctuating Wetland
Title
Mechanisms That Generate Resource Pulses in a Fluctuating Wetland.
Creator
Botson, Bryan A., Gawlik, Dale E., Trexler, Joel C., Hewitt, Judi
Date Issued
2016-07-22
PURL
http://purl.flvc.org/fau/fd/FAUIR000092
Format
Citation
Pseudopterosin A: Protection of Synaptic Function and Potential as a Neuromodulatory Agent
Title
Pseudopterosin A: Protection of Synaptic Function and Potential as a Neuromodulatory Agent.
Creator
Caplan, Stacee Lee, Zheng, Bo, Dawson-Scully, Ken, White, Catherine, West, Lyndon
Date Issued
2016-03-10
PURL
http://purl.flvc.org/fau/fd/FAUIR000130
Format
Citation
Quantification of Massive Seasonal Aggregations of Blacktip Sharks (Carcharhinus limbatus) in Southeast Florida
Title
Quantification of Massive Seasonal Aggregations of Blacktip Sharks (Carcharhinus limbatus) in Southeast Florida.
Creator
Kajiura, Stephen M., Tellman, Shari L.
Abstract/Description
Southeast Florida witnesses an enormous seasonal influx of upper trophic level marine predators each year as massive aggregations of migrating blacktip sharks (Carcharhinus limbatus) overwinter in nearshore waters. The narrow shelf and close proximity of the Gulf Stream current to the Palm Beach County shoreline drive tens of thousands of sharks to the shallow, coastal environment. This natural bottleneck provides a unique opportunity to estimate relative abundance. Over a four year period...
Show moreSoutheast Florida witnesses an enormous seasonal influx of upper trophic level marine predators each year as massive aggregations of migrating blacktip sharks (Carcharhinus limbatus) overwinter in nearshore waters. The narrow shelf and close proximity of the Gulf Stream current to the Palm Beach County shoreline drive tens of thousands of sharks to the shallow, coastal environment. This natural bottleneck provides a unique opportunity to estimate relative abundance. Over a four year period from 2011–2014, an aerial survey was flown approximately biweekly along the length of Palm Beach County. A high definition video camera and digital still camera mounted out of the airplane window provided a continuous record of the belt transect which extended 200 m seaward from the shoreline between Boca Raton Inlet and Jupiter Inlet. The number of sharks within the survey transect was directly counted from the video. Shark abundance peaked in the winter (January-March) with a maximum in 2011 of 12,128 individuals counted within the 75.6 km-2 belt transect. This resulted in a maximum density of 803.2 sharks km-2. By the late spring (April-May), shark abundance had sharply declined to 1.1% of its peak, where it remained until spiking again in January of the following year. Shark abundance was inversely correlated with water temperature and large numbers of sharks were found only when water temperatures were less than 25°C. Shark abundance was also correlated with day of the year but not with barometric pressure. Although shark abundance was not correlated with photoperiod, the departure of the sharks from southeast Florida occurred around the vernal equinox. The shark migration along the United States eastern seaboard corresponds spatially and temporally with the spawning aggregations of various baitfish species. These baseline abundance data can be compared to future studies to determine if shark population size is changing and if sharks are restricting their southward migration as global water temperatures increase.
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Date Issued
2016-03-30
PURL
http://purl.flvc.org/fau/fd/FAUIR000074
Format
Citation
Determining habitat quality for species that demonstrate dynamic habitat selection
Title
Determining habitat quality for species that demonstrate dynamic habitat selection.
Creator
Beerens, James M., Frederick, Peter C., Noonburg, Erik G., Gawlik, Dale E.
Date Issued
2015-11-19
PURL
http://purl.flvc.org/fau/fd/FAUIR000141
Format
Citation
CytoregR inhibits growth and proliferation of human adenocarcinoma cells via induction of apoptosis
Title
CytoregR inhibits growth and proliferation of human adenocarcinoma cells via induction of apoptosis.
Creator
Kumi-Diaka, James, Hassanhi, M., Brown, Jayann Marie, Merchant, Kendra T., Garcia, C., Jimenez, W.
Date Issued
2006-01-09
PURL
http://purl.flvc.org/fcla/dt/3327155
Format
Document (PDF)
Emerging Insights on Brazilian Pepper Tree (Schinus terebinthifolius) Invasion: The Potential Role of Soil Microorganisms
Title
Emerging Insights on Brazilian Pepper Tree (Schinus terebinthifolius) Invasion: The Potential Role of Soil Microorganisms.
Creator
Dawkins, Karim, Esiobu, Nwadiuto
Date Issued
2016-05-24
PURL
http://purl.flvc.org/fau/fd/FAUIR000138
Format
Citation
Expression of human amyloid precursor protein in the skeletal muscles of Drosophila results in age- and activity-dependent muscle weakenss
Title
Expression of human amyloid precursor protein in the skeletal muscles of Drosophila results in age- and activity-dependent muscle weakenss.
Creator
Kim, Chul, Srivastava, Sapeckshita, Rice, Marian, Godenschwege, Tanja A., Bentley, Brooke, Ravi, Saranya, Shao, Shuang, Woodard, Craig T., Schwartz, Lawrence M.
Date Issued
2011-04-25
PURL
http://purl.flvc.org/fcla/dt/3327608
Format
Document (PDF)
The PHR proteins: intracellular signaling hubs in neuronal development and axon degeneration
Title
The PHR proteins: intracellular signaling hubs in neuronal development and axon degeneration.
Creator
Grill, Brock, Murphey, Rodney K., Borgen, Melissa A.
Abstract/Description
During development, a coordinated and integrated series of events must be accomplished in order to generate functional neural circuits. Axons must navigate toward target cells, build synaptic connections, and terminate outgrowth. The PHR proteins (consisting of mammalian Phr1/MYCBP2, Drosophila Highwire and C. elegans RPM-1) function in each of these events in development. Here, we review PHR function across species, as well as the myriad of signaling pathways PHR proteins regulate. These...
Show moreDuring development, a coordinated and integrated series of events must be accomplished in order to generate functional neural circuits. Axons must navigate toward target cells, build synaptic connections, and terminate outgrowth. The PHR proteins (consisting of mammalian Phr1/MYCBP2, Drosophila Highwire and C. elegans RPM-1) function in each of these events in development. Here, we review PHR function across species, as well as the myriad of signaling pathways PHR proteins regulate. These findings collectively suggest that the PHR proteins are intracellular signaling hubs, a concept we explore in depth. Consistent with prominent developmental functions, genetic links have begun to emerge between PHR signaling networks and neurodevelopmental disorders, such as autism, schizophrenia and intellectual disability. Finally, we discuss the recent and important finding that PHR proteins regulate axon degeneration, which has further heightened interest in this fascinating group of molecules.
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Date Issued
2016-12-23
PURL
http://purl.flvc.org/fau/fd/FAUIR000039
Format
Citation
Sulindac Enhances the Killing of Cancer Cells Exposed to Oxidative Stress
Title
Sulindac Enhances the Killing of Cancer Cells Exposed to Oxidative Stress.
Creator
Marchetti, Maria, Resnick, Lionel, Gamliel, Edna, Kesaraju, Shailaja, Weissbach, Herbert, Binninger, David, Bauer, Joseph Alan
Date Issued
2009-06-05
PURL
http://purl.flvc.org/fau/fd/FAUIR000108
Format
Citation
Linking Dynamic Habitat Selection with Wading Bird Foraging Distributions across Resource Gradients
Title
Linking Dynamic Habitat Selection with Wading Bird Foraging Distributions across Resource Gradients.
Creator
Beerens, James M., Noonburg, Erik G., Gawlik, Dale E., Gao, Chang-Qing
Date Issued
2015-06-24
PURL
http://purl.flvc.org/fau/fd/FAUIR000142
Format
Citation
Potential mechanism of phytochemical-induced apoptosis in human prostate adenocarcinoma cells: Therapeutic synergy in genistein and β-lapachone combination treatment
Title
Potential mechanism of phytochemical-induced apoptosis in human prostate adenocarcinoma cells: Therapeutic synergy in genistein and β-lapachone combination treatment.
Creator
Kumi-Diaka, James, Saddler, Shawnette Simone, Aller, Alex, Brown, Jayann Marie
Date Issued
2004-08-17
PURL
http://purl.flvc.org/fcla/dt/3327156
Format
Document (PDF)
Biomass offsets little or none of permafrost carbon release from soils, streams, and wildfire: an expert assessment
Title
Biomass offsets little or none of permafrost carbon release from soils, streams, and wildfire: an expert assessment.
Creator
Abbott, Benjamin W., Jones, Jeremy B., Schuur, Edward A. G., Chapin III, F. Stuart, Bowden, William B., Bret-Harte, M. Syndonia, Epstein, Howard E., Flannigan, Michael D., Harms, Tamara K., Hollingsworth, Teresa N., Mack, Michelle C., McGuire, A. David, Natali, Susan M., Rocha, Adrian V., Tank, Suzanne E., Turetsky, Merritt R., Vonk, Jorien E., Wickland, Kimberly P., Aiken, George R., Alexander, Heather D., Amon, Rainer M. W., Benscoter, Brian, Bergeron, Yves, Bishop, Kevin, Blarquez, Olivier, Bond-Lamberty, Ben, Breen, Amy L., Buffam, Ishi, Cai, Yihua, Carcaillet, Christopher, Carey, Sean K., Chen, Jing M., Chen, Han Y. H., Christensen, Torben R., Cooper, Lee W., Cornelissen, J. Hans C., de Groot, William J., DeLuca, Thomas H., Dorrepaal, Ellen, Fetcher, Ned, Finlay, Jacques C., Forbes, Bruce C., French, Nancy H. F., Gauthier, Sylvie, Girardin, Martin P., Goetz, Scott J., Goldammer, Johann G., Gough, Laura, Grogan, Paul, Guo, Laodong, Higuera, Philip E., Hinzman, Larry, Hu, Feng Sheng, Hugelius, Gustaf, Jafarov, Elchin E., Jandt, Randi, Johnstone, Jill F., Jan Karlsson, Kasischke, Eric S., Kattner, Gerhard, Kelly, Ryan, Keuper, Frida, Kling, George W., Kortelainen, Pirkko, Kouki, Jari, Kuhry, Peter, Laudon, Hjalmar, Laurion, Isabelle, Macdonald, Robie W., Mann, Paul J., Martikainen, Pertti J., McClelland, James W., Molau, Ulf, Oberbauer, Steven F., Olefeldt, David, Paré, David, Parisien, Marc-André, Payette, Serge, Peng, Changhui, Pokrovsky, Oleg S., Rastetter, Edward B., Raymond, Peter A., Raynolds, Martha K., Rein, Guillermo, Reynolds, James F., Robards, Martin, Rogers, Brendan M., Schädel, Christina, Schaefer, Kevin, Schmidt, Inger K., Shvidenko, Anatoly, Sky, Jasper, Spencer, Robert G. M., Starr, Gregory, Striegl, Robert G., Teisserenc, Roman, Tranvik, Lars J., Virtanen, Tarmo, Welker, Jeffrey M., Zimov, Sergei
Date Issued
2016-03-07
PURL
http://purl.flvc.org/fau/fd/FAUIR000121
Format
Citation
Biotic Control of Surface pH and Evidence of Light-Induced H+ Pumping and Ca2+-H+ Exchange in a Tropical Crustose Coralline Alga
Title
Biotic Control of Surface pH and Evidence of Light-Induced H+ Pumping and Ca2+-H+ Exchange in a Tropical Crustose Coralline Alga.
Creator
Hofmann, Laurie C., Koch, Marguerite, de Beer, Dirk, Chin, Wei-Chun
Abstract/Description
Presently, an incomplete mechanistic understanding of tropical reef macroalgae photosynthesis and calcification restricts predictions of how these important autotrophs will respond to global change. Therefore, we investigated the mechanistic link between inorganic carbon uptake pathways, photosynthesis and calcification in a tropical crustose coralline alga (CCA) using microsensors. We measured pH, oxygen (O2), and calcium (Ca^2+) dynamics and fluxes at the thallus surface under ambient (8.1)...
Show morePresently, an incomplete mechanistic understanding of tropical reef macroalgae photosynthesis and calcification restricts predictions of how these important autotrophs will respond to global change. Therefore, we investigated the mechanistic link between inorganic carbon uptake pathways, photosynthesis and calcification in a tropical crustose coralline alga (CCA) using microsensors. We measured pH, oxygen (O2), and calcium (Ca^2+) dynamics and fluxes at the thallus surface under ambient (8.1) and low (7.8) seawater pH (pHSW) and across a range of irradiances. Acetazolamide (AZ) was used to inhibit extracellular carbonic anhydrase (CAext), which mediates hydrolysis of HCO3-, and 4,40 diisothiocyanatostilbene- 2,2'-disulphonate (DIDS) that blocks direct HCO3- uptake by anion exchange transport. Both inhibited photosynthesis, suggesting both diffusive uptake of CO2 via HCO3- hydrolysis to CO2 and direct HCO3- ion transport are important in this CCA. Surface pH was raised approximately 0.3 units at saturating irradiance, but less when CAext was inhibited. Surface pH was lower at pHSW 7.8 than pHSW 8.1 in the dark, but not in the light. The Ca^2+ fluxes were large, complex and temporally variable, but revealed net Ca2+ uptake under all conditions. The temporal variability in Ca^2+ dynamics was potentially related to localized dissolution during epithallial cell sloughing, a strategy of CCA to remove epiphytes. Simultaneous Ca^2+ and pH dynamics suggest the presence of Ca^2+/H^+ exchange. Rapid light-induced H^+ surface dynamics that continued after inhibition of photosynthesis revealed the presence of a light-mediated, but photosynthesis-independent, proton pump. Thus, the study indicates metabolic control of surface pH can occur in CCA through photosynthesis and light-inducible H^+ pumps. Our results suggest that complex light-induced ion pumps play an important role in biological processes related to inorganic carbon uptake and calcification in CCA.
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Date Issued
2016-07-26
PURL
http://purl.flvc.org/fau/fd/FAUIR000029
Format
Citation
cGMP-Dependent Protein Kinase Inhibition Extends the Upper Temperature Limit of Stimulus-Evoked Calcium Responses in Motoneuronal Boutons of Drosophila melanogaster Larvae
Title
cGMP-Dependent Protein Kinase Inhibition Extends the Upper Temperature Limit of Stimulus-Evoked Calcium Responses in Motoneuronal Boutons of Drosophila melanogaster Larvae.
Creator
Krill, Jennifer L., Dawson-Scully, Ken, McCabe, Brian D.
Abstract/Description
While the mammalian brain functions within a very narrow range of oxygen concentrations and temperatures, the fruit fly, Drosophila melanogaster, has employed strategies to deal with a much wider range of acute environmental stressors. The foraging (for) gene encodes the cGMP-dependent protein kinase (PKG), has been shown to regulate thermotolerance in many stress-adapted species, including Drosophila, and could be a potential therapeutic target in the treatment of hyperthermia in mammals....
Show moreWhile the mammalian brain functions within a very narrow range of oxygen concentrations and temperatures, the fruit fly, Drosophila melanogaster, has employed strategies to deal with a much wider range of acute environmental stressors. The foraging (for) gene encodes the cGMP-dependent protein kinase (PKG), has been shown to regulate thermotolerance in many stress-adapted species, including Drosophila, and could be a potential therapeutic target in the treatment of hyperthermia in mammals. Whereas previous thermotolerance studies have looked at the effects of PKG variation on Drosophila behavior or excitatory postsynaptic potentials at the neuromuscular junction (NMJ), little is known about PKG effects on presynaptic mechanisms. In this study, we characterize presynaptic calcium ([Ca^2+]i) dynamics at the Drosophila larval NMJ to determine the effects of high temperature stress on synaptic transmission. We investigated the neuroprotective role of PKG modulation both genetically using RNA interference (RNAi), and pharmacologically, to determine if and how PKG affects presynaptic [Ca^2+]i dynamics during hyperthermia. We found that PKG activity modulates presynaptic neuronal Ca^2+ responses during acute hyperthermia, where PKG activation makes neurons more sensitive to temperatureinduced failure of Ca^2+ flux and PKG inhibition confers thermotolerance and maintains normal Ca^2+ dynamics under the same conditions. Targeted motoneuronal knockdown of PKG using RNAi demonstrated that decreased PKG expression was sufficient to confer thermoprotection. These results demonstrate that the PKG pathway regulates presynaptic motoneuronal Ca^2+ signaling to influence thermotolerance of presynaptic function during acute hyperthermia.
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Date Issued
2016-10-06
PURL
http://purl.flvc.org/fau/fd/FAUIR000079
Format
Citation

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