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Title: DEVELOPMENT OF AN ELASTIC POLYMER-BASED DRUG DELIVERY SYSTEM FOR TISSUE REGENERATION.
Creator: Firoozi, Negar, Kang, Yunqing, Florida Atlantic University, College of Engineering and Computer Science, Department of Ocean and Mechanical Engineering
Abstract/Description: In spite of the vast research on polymer-based tissue regeneration, extensive studies to develop an elastic and cell-promoting polymer biomaterial are still ongoing. However, using a renewable resource and a simple, environment-friendly synthesis route to synthesize an elastic polymer has not been successfully achieved yet. The objective of this work was to develop an elastic polymer for tissue engineering and drug delivery applications by using non-toxic, inexpensive and renewable monomers....
Show moreIn spite of the vast research on polymer-based tissue regeneration, extensive studies to develop an elastic and cell-promoting polymer biomaterial are still ongoing. However, using a renewable resource and a simple, environment-friendly synthesis route to synthesize an elastic polymer has not been successfully achieved yet. The objective of this work was to develop an elastic polymer for tissue engineering and drug delivery applications by using non-toxic, inexpensive and renewable monomers. A new nature-derived renewable material, xylitol, was used to synthesize an elastic polymer with the presence of a crosslinking agent, dodecanedioic acid. Here a simple melt condensation polymerization method was used to synthesize the poly(xylitoldodecanedioic acid)(PXDDA). The physicochemical and biological properties of the new PXDDA polymer were characterized. Fourier transform infrared (FTIR) confirmed the formation of ester bonding in the polymer structure, and thermal analysis demonstrated that the polymer was completely amorphous. The polymer shows high elasticity. Increasing the molar ratio of dodecanedioic acid resulted in higher hydrophobicity and lower glass transition temperature. Further, the polymer degradation and in vitro dye release studies revealed that the degradation and dye release from the polymer became slower when the amount of dodecanedioic acid in the composite increased.
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Date Issued: 2019
PURL: http://purl.flvc.org/fau/fd/FA00013306
Subject Headings: Drug Delivery Systems, Polymers, Tissue Engineering, Xylitol
Format: Document (PDF)

Title: Development of a Thermosensitive Trimethyl Chitosan Hydrogel for in situ Tissue Engineering.
Creator: Qian, Enze, Kang, Yunqing, Florida Atlantic University, College of Engineering and Computer Science, Department of Ocean and Mechanical Engineering
Abstract/Description: Chitosan was widely studied for applications in tissue regeneration, because of its biodegradability and biocompatibility. However, its insolubility in a neutral solution and long gelation time limit its wide application in tissue engineering. In this thesis, a new chitosan-based biomaterial was synthesized, and its chemical structure and solubility were characterized. Afterwards, the gelation properties (crosslinker, crosslink time, swelling ratio, drug release and biocompatibility) of TMC...
Show moreChitosan was widely studied for applications in tissue regeneration, because of its biodegradability and biocompatibility. However, its insolubility in a neutral solution and long gelation time limit its wide application in tissue engineering. In this thesis, a new chitosan-based biomaterial was synthesized, and its chemical structure and solubility were characterized. Afterwards, the gelation properties (crosslinker, crosslink time, swelling ratio, drug release and biocompatibility) of TMC material was investigated. Results show that TMC has higher water solubility than chitosan. The TMC liquid solution can transform to a hydrogel quickly at body temperature. The formed hydrogel controlled the release of the model protein. Cytotoxicity result shows the cationic TMC hydrogel brings a toxic effect on stromal cells but it may have the potential to inhibit bacteria or cancer cells, although more studied are required to confirm its potential functions. In summary, this new TMC hydrogel has a promising potential in biomedical fields.
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Date Issued: 2018
PURL: http://purl.flvc.org/fau/fd/FA00013095
Subject Headings: Tissue engineering., Chitosan--Biotechnology., Hydrogels.
Format: Document (PDF)

Title: Ultrastructure of somatic tissues in theovaries of a chaetognath (Ferosagitta hispida).
Creator: Shinn, G. L., Harbor Branch Oceanographic Institute
Date Issued: 1992
PURL: http://purl.flvc.org/fau/fd/FA00007087
Subject Headings: Ultrastructure (Biology), Ovary, Chaetognatha, Somatic cells, Tissues, Transmission electron microscopy
Format: Document (PDF)

Title: DEVELOPMENT OF MULTIFUNCTIONAL BETA-TRICALCIUM PHOSPHATE SCAFFOLDS FOR ANGIOGENESIS AND OSTEOGENESIS.
Creator: Qian, Enze, Kang, Yunqing, Florida Atlantic University, Department of Ocean and Mechanical Engineering, College of Engineering and Computer Science
Abstract/Description: Rapid and efficient vascularization is still a considerable challenge of a tissue engineered β-tricalcium phosphate (β-TCP) scaffold. To overcome this challenge, branched channels were created in the porous scaffold to stimulate the instant flow of blood supply. The branched channeled porous β-TCP scaffold was fabricated using 3D printing and template-casting method. Human bone mesenchymal stem cells (hBMSC) and human umbilical vein endothelial cells (HUVEC) were seeded in the scaffolds and...
Show moreRapid and efficient vascularization is still a considerable challenge of a tissue engineered β-tricalcium phosphate (β-TCP) scaffold. To overcome this challenge, branched channels were created in the porous scaffold to stimulate the instant flow of blood supply. The branched channeled porous β-TCP scaffold was fabricated using 3D printing and template-casting method. Human bone mesenchymal stem cells (hBMSC) and human umbilical vein endothelial cells (HUVEC) were seeded in the scaffolds and characterized through double-stranded DNA (dsDNA) assay, alkaline phosphatase (ALP) assay and cell migration. Scaffolds were then implanted in the subcutaneous pockets in mice. Hematoxylin and eosin staining and Immunohistochemical staining on vascularization, bone-related markers were carried out. Results showed that branched channels significantly promoted HUVECs’ infiltration, migration, proliferation, and angiogenesis and also promote the proliferation and osteogenesis differentiation of hBMSCs. Scaffolds did not show significant pro-inflammatory effects. In vivo results showed that in the early stage after implantation, cells significantly migrated into branched channeled scaffolds compared to non-channeled and straight channeled scaffolds. More and matured blood vessels formed in the branched channeled scaffolds compared to in non-channeled and straight channeled scaffolds. Besides promoting vascularization, the branched channels also stimulated the infiltration of bone-related cells into the scaffolds. These results suggested that the geometric design of branched channels in the porous β-TCP scaffold promoted rapid vascularization and potentially stimulated bone cell recruitment. To further enhance the function of the scaffold to promote the MSCs differentiation, MnO2 hollow and solid nanoparticles were doped into the scaffold with different concentrations.
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Date Issued: 2023
PURL: http://purl.flvc.org/fau/fd/FA00014193
Subject Headings: Tissue engineering, Bone Regeneration, Beta-tricalcium phosphate
Format: Document (PDF)

Title: An organ procurement coordinator's effect on referral rates made by emergency room nurses.
Creator: Jennings, Tabatha Lynn., Florida Atlantic University, Winland-Brown, Jill
Abstract/Description: This study presents information on the effect an organ procurement coordinator had on referral rates made by emergency room nurses. Retrospective data were analyzed after a period of eight months of data collection. These data included a pre-test/post-test which was given to emergency room nursing staff in southeast Florida. Inservice education was given by an organ procurement coordinator during an eight month period. The number of referrals were analyzed at the beginning and end of this...
Show moreThis study presents information on the effect an organ procurement coordinator had on referral rates made by emergency room nurses. Retrospective data were analyzed after a period of eight months of data collection. These data included a pre-test/post-test which was given to emergency room nursing staff in southeast Florida. Inservice education was given by an organ procurement coordinator during an eight month period. The number of referrals were analyzed at the beginning and end of this period. There was a positive correlation between the increased knowledge of the emergency room nursing staff and the increase in referral rates. This information gives support to the significance of the organ procurement coordinator's role as educator to emergency room nurses. By increasing knowledge regarding the organ donation process, referral rates were increased, providing more opportunity for potential organ donors. This information can be useful for future programs to increase referral rates made by emergency room nurses. Further implications for practice, education, and research are discussed.
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Date Issued: 1998
PURL: http://purl.flvc.org/fcla/dt/15550
Subject Headings: Donation of organs, tissues, etc, Nurses--In-service training, Procurement of organs, tissues, etc, Emergency medical personnel
Format: Document (PDF)

Title: ENGINEERING CHANNELS IN POROUS CALCIUM PHOSPHATE BIOCERAMIC SCAFFOLDS FOR BONE TISSUE REGENERATION.
Creator: Wang, Xuesong, Kang, Yunqing, Florida Atlantic University, Department of Ocean and Mechanical Engineering, College of Engineering and Computer Science
Abstract/Description: Inadequate nutrition exchange and slow transportation in a porous scaffold often resulted in insufficient vasculature formation, which hindered rapid bone regeneration. In this study, interconnected porous beta-tricalcium phosphate (b-TCP) scaffolds with channeled geometry were fabricated. In vitro fluid transportation and degradation of the scaffolds were performed. Cell attachment, migration, proliferation, and differentiation were carried out under both static and dynamic culturing...
Show moreInadequate nutrition exchange and slow transportation in a porous scaffold often resulted in insufficient vasculature formation, which hindered rapid bone regeneration. In this study, interconnected porous beta-tricalcium phosphate (b-TCP) scaffolds with channeled geometry were fabricated. In vitro fluid transportation and degradation of the scaffolds were performed. Cell attachment, migration, proliferation, and differentiation were carried out under both static and dynamic culturing conditions. A computational simulation model and a series of immunofluorescent staining were implemented to understand the mechanism of cell behavior in respond to different scaffolds geometry. We then implanted scaffolds into rat critical-sized calvarial defects to further evaluate channels’ function on bone regeneration in vivo. Results showed that multiple channeled geometry significantly accelerated the release of Ca2+ and increased the fluid diffusion efficiency. Moreover, multiple channels promoted human umbilical vein endothelial cells (HUVECs) infiltration, migration, besides prominently promoted alkaline phosphatase (ALP) activity, and up-regulated osteogenic gene expression in human bone marrow mesenchymal stem cells (hBMSCs) at both static and dynamic culturing conditions in vitro. The expression of both cell migration related protein a5 and angiogenesis related protein CD31 were upregulated by multiple channels in HUVECs. And the expression of mechanosensing markers, focal adhesion kinase (FAK), polymeric filamentous actin (Factin), and Yes-associated protein-1 (YAP-1) were highly stimulated by multiple channels in hBMSCs. The in vivo implantation and characterization results demonstrated more bone formation inside multiple-channeled scaffolds compared to non-channeled scaffolds. Multiple channels accelerated collagen type I, Bone Sialoprotein (Bsp), Osteocalcin (OC) protein expression prominently. The angiogenesis related protein CD31 staining displayed longer and more vasculature structures on multiple-channeled scaffolds compared to nonchanneled scaffolds. Fluorescent images of the fluorochrome labeled samples exhibited considerably more mineral deposition on multiple-channeled scaffolds than non-channeled scaffolds. All the findings suggested that the addition of multiple channels in the porous b-TCP scaffold is very promising approach to promote vascularization and bone tissue regeneration.
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Date Issued: 2019
PURL: http://purl.flvc.org/fau/fd/FA00013426
Subject Headings: Tissue Engineering, Bone and Bones, Bone regeneration, Calcium Phosphates, Biocompatible Materials
Format: Document (PDF)

Title: A Dosimetric Comparison of 3D-CRT, IMRT, and SAVI HDR via NTCP/TCP and DVH Analysis of Critical Organs for Breast Cancer.
Creator: Wisnoskie, Sarah, Pella, Silvia, Florida Atlantic University, Charles E. Schmidt College of Science, Department of Physics
Abstract/Description: Accelerated Partial Breast Irradiation (APBI) is a common treatment of breast cancer with many modalities including 3D Conformal Radiation Therapy (3D-CRT), Intensity Modulated Radiation Therapy (IMRT), and High Dose Rate Brachytherapy (HDR). In this research, a retrospective analysis of patient’s data was performed to analyze the NTCP/TCP (Normal Tissue Complication Probability/Tumor Control Probability) and Dose Volume Histogram (DVH) parameters for HDR with SAVI, 3D, and IMRT and compare...
Show moreAccelerated Partial Breast Irradiation (APBI) is a common treatment of breast cancer with many modalities including 3D Conformal Radiation Therapy (3D-CRT), Intensity Modulated Radiation Therapy (IMRT), and High Dose Rate Brachytherapy (HDR). In this research, a retrospective analysis of patient’s data was performed to analyze the NTCP/TCP (Normal Tissue Complication Probability/Tumor Control Probability) and Dose Volume Histogram (DVH) parameters for HDR with SAVI, 3D, and IMRT and compare them focusing on critical organs such as the heart, ipsilateral lung, chest wall, ribs, and skin. TCP was 90.275%, 55.948%, and 53.369% for HDR, 3D, and IMRT respectively. The ribs were the most sensitive critical organ for all 3 modalities with a mean NTCP of 8%, 15%, and 8% for HDR, 3D, and IMRT respectively. DVH analysis showed HDR spares critical organs more than EBRT except for 2 patients receiving high doses to the ribs and chest wall.
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Date Issued: 2019
PURL: http://purl.flvc.org/fau/fd/FA00013281
Subject Headings: Radiation dosimetry--Evaluation, Breast--Cancer--Treatment, Organs, Tissues--Effect of radiation on
Format: Document (PDF)

Title: Thermodynamic profiles of the interactions of suramin, chondroitin sulfate, and pentosan polysulfate with the inhibitory domain of tissue inhibitor of metalloproteinases 3.
Creator: Logue, Timothy, Brew, Keith, Florida Atlantic University, Charles E. Schmidt College of Science, Department of Biological Sciences
Abstract/Description: Tissue inhibitor of metalloproteinase-3 (TIMP-3) is a protein with multiple functions that include regulating the turnover of the extracellular matrix (ECM) by inhibiting members of the metzincin family. Extracellular levels of soluble TIMP-3 are low, reflecting its binding to components of the ECM including sulfated glycosaminoglycans (SGAGs) and its endocytosis by low density lipoprotein receptor-related protein 1. Because TIMP-3 inhibits ECM-degrading enzymes, the ability of SGAG mimetics...
Show moreTissue inhibitor of metalloproteinase-3 (TIMP-3) is a protein with multiple functions that include regulating the turnover of the extracellular matrix (ECM) by inhibiting members of the metzincin family. Extracellular levels of soluble TIMP-3 are low, reflecting its binding to components of the ECM including sulfated glycosaminoglycans (SGAGs) and its endocytosis by low density lipoprotein receptor-related protein 1. Because TIMP-3 inhibits ECM-degrading enzymes, the ability of SGAG mimetics to elevate extracellular concentrations of TIMP3 is of interest for osteoarthritis treatment. However, previous studies of such interactions have utilized immobilized forms of the protein or ligands. Here we have quantified the thermodynamics of the interactions of the inhibitory domain of TIMP-3 with chondroitin sulfate (CS), pentosan polysulfate (PPS) and suramin in solution using isothermal titration calorimetry. All three interactions are driven by a (favorable) negative enthalpy ychange combined with an unfavorable decrease in entropy. The heat capacity change (ΔCp) for the interaction of N-TIMP-3 with CS, PPS, or suramin is essentially zero, indicating an insignificant contribution from the hydrophobic effect. Based on the effects of ionic strength on the interaction of N-TIMP-3 with suramin, their interaction appears to be driven by electrostatic interactions. Modeling supports the view that the negatively charged sulfates of CS, PPS, and suramin interact with a cationic region on N-TIMP-3 that includes Lys -26, -27, -30, and -possibly 76 on the opposite face of TIMP-3 from its reactive site for metalloproteases.
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Date Issued: 2019
PURL: http://purl.flvc.org/fau/fd/FA00013328
Subject Headings: Tissue Inhibitor of Metalloproteinases, Osteoarthritis--Treatment, Suramin, Chondroitin Sulfates, Pentosans
Format: Document (PDF)

Title: The lived experience of the spouses of transplant recipients.
Creator: Stecher, Jo Anne., Christine E. Lynn College of Nursing
Abstract/Description: The numbers of transplant surgeries continue to rise in the U.S. This results in a greater number of caregivers who are present in the recipients' lives. Most often these caregivers are spouses. Transplant spouses present with emotional needs, which have been expressed in this study. Nurses, especially those who work with the spouses of transplant candidates and recipients, could be appreciative of the requirements that have been told by these spouses. Six women and two men were interviewed...
Show moreThe numbers of transplant surgeries continue to rise in the U.S. This results in a greater number of caregivers who are present in the recipients' lives. Most often these caregivers are spouses. Transplant spouses present with emotional needs, which have been expressed in this study. Nurses, especially those who work with the spouses of transplant candidates and recipients, could be appreciative of the requirements that have been told by these spouses. Six women and two men were interviewed for this study. Their stories were analyzed using a phenomenological approach and five themes emerged from the data. The themes that surfaced included uncertainty, support, thankfulness and a positive approach, intimacy and the relationship as a couple, and guilt. Two general structures then evolved from these themes to include adaptation and belief in self and others. The general structures revealed the ways the spouses learned to live during the transplant journey.
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Date Issued: 2009
PURL: http://purl.flvc.org/FAU/367765
Subject Headings: Transplantation of organs, tissues, etc, Family relationships, Caregivers, Conduct of life, Stress management
Format: Document (PDF)

Title: CRYOPRESERVATION OF PLANT PROTOPLASTS.
Creator: MAZUR, RICHARD ALAN, Florida Atlantic University
Abstract/Description: Plant cells and protoplasts were frozen and maintained at -196 C for five days. After thawing at 37 C their viability was assessed by trypan blue dye exclusion. Protoplasts were isolated by enzymatic digestion of the cell walls of two day cultures of Bromus inermus (Leyss), Daucus carota (L.), and Glycine max (L.) Merr. The survival of brome grass protoplasts was 59.45% ± 3.59, that of carrot 52.09% ± 18.99 in 1.4 M and 0.7 M glycerol respectively. With cells the survival was 35.64% ± 2.07...
Show morePlant cells and protoplasts were frozen and maintained at -196 C for five days. After thawing at 37 C their viability was assessed by trypan blue dye exclusion. Protoplasts were isolated by enzymatic digestion of the cell walls of two day cultures of Bromus inermus (Leyss), Daucus carota (L.), and Glycine max (L.) Merr. The survival of brome grass protoplasts was 59.45% ± 3.59, that of carrot 52.09% ± 18.99 in 1.4 M and 0.7 M glycerol respectively. With cells the survival was 35.64% ± 2.07 for brome grass and 39.45% ± 2.47 for carrot. Protoplasts frozen in a three step protocol (+4, -20, -58 C) exhibited 10% greater survival than those frozen directly at -58 C. The isolation of protoplasts in medium containing 0. 7 M glycerol was beneficial. A direct relationship between cell wall removal and an increase in protoplast survival was evident. Protoplasts which had been frozen (-196 C) for five days can be cultured as evidenced by cell wall regeneration, cell division, and cyclosis.
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Date Issued: 1977
PURL: http://purl.flvc.org/fcla/dt/13871
Subject Headings: Plant protoplasts, Cryobiology, Plant cells and tissues, Plants--Effect of cold on
Format: Document (PDF)

Title: THE LIVED EXPERIENCE OF FAMILIES WHO DONATE THEIR NEONATE’S ORGANS.
Creator: Etheridge-Bagley, Erin, Hawthorne, Dawn, Florida Atlantic University, Christine E. Lynn College of Nursing, Christine E. Lynn College of Nursing
Abstract/Description: The purpose of this qualitative research study was to explore the lived experience of families who donated their neonate’s organs at the end of life. The experiences of five mothers and one father were elicited from those who experienced this phenomenon. Heideggerian hermeneutic phenomenology served as the methodology as well as the guiding philosophy for this research study. Watson’s theory of Unitary Caring Science and the Caritas Processed provided the caring lens through which the...
Show moreThe purpose of this qualitative research study was to explore the lived experience of families who donated their neonate’s organs at the end of life. The experiences of five mothers and one father were elicited from those who experienced this phenomenon. Heideggerian hermeneutic phenomenology served as the methodology as well as the guiding philosophy for this research study. Watson’s theory of Unitary Caring Science and the Caritas Processed provided the caring lens through which the research was completed. Deikelmann’s seven stage process for analysis was employed and through which four relative themes emerged: Enhancing the Fullness of the Baby, Celebrating the Ongoing Presencing of the Baby Within the Family, Ameliorating Grief through the Hope of Donation, and Being Embraced Within a Healing Environment. The four relational themes are represented with an aesthetic interpretation of the experience.
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Date Issued: 2023
PURL: http://purl.flvc.org/fau/fd/FA00014178
Subject Headings: Donation of organs, tissues, etc., Newborn infants, Organ donors--Family relationships, Nursing, Caring
Format: Document (PDF)

Title: Engineering of tissue inhibitor of metalloproteinases mutants as potential therapeutics.
Creator: Nagase, Hideaki, Brew, Keith
Abstract/Description: Matrix metalloproteinases (MMPs) play a central role in many biological processes such as development, morphogenesis and wound healing, but their unbalanced activities are implicated innumerous disease processes such as arthritis, cancer metastasis, atherosclerosis, nephritis and fibrosis. One of the key mechanisms to control MMP activities is inhibition by endogenous inhibitors called tissue inhibitors of metalloproteinases (TIMPs). This review highlights the structures and inhibition...
Show moreMatrix metalloproteinases (MMPs) play a central role in many biological processes such as development, morphogenesis and wound healing, but their unbalanced activities are implicated innumerous disease processes such as arthritis, cancer metastasis, atherosclerosis, nephritis and fibrosis. One of the key mechanisms to control MMP activities is inhibition by endogenous inhibitors called tissue inhibitors of metalloproteinases (TIMPs). This review highlights the structures and inhibition mechanism of TIMPs, the biological activities of TIMPs, the unique properties of TIMP-3, and the altered specificity towards MMPs achieved by mutagenesis. A potential therapeutic use of TIMP variants is discussed.
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Date Issued: 2002-04-02
PURL: http://purl.flvc.org/fcla/dt/3327266
Subject Headings: Gene Therapy --Methods, Genetic Engineering --methods, Protein Structure, Tertiary, Rheumatic Diseases --therapy, Tissue Inhibitor of Metalloproteinases, Wound Healing --physiology, Metalloproteinases --Inhibitors --Therapeutic use
Format: Document (PDF)

Title: Healing Transcendence: Social Media Use by Persons in the Transplant Journey.
Creator: Grumme, Valarie S., Gordon, Shirley C., Florida Atlantic University, Christine E. Lynn College of Nursing
Abstract/Description: An increasing number of individuals are looking for health information, interacting with health care providers, and participating in health-related online support groups The virtual landscape of the internet offers the opportunity for individuals to establish contact and relationships with persons having similar health concerns anywhere, anytime The phenomenon of health-related social media use generated an interest in why persons in the transplant journey chose to participate in an online...
Show moreAn increasing number of individuals are looking for health information, interacting with health care providers, and participating in health-related online support groups The virtual landscape of the internet offers the opportunity for individuals to establish contact and relationships with persons having similar health concerns anywhere, anytime The phenomenon of health-related social media use generated an interest in why persons in the transplant journey chose to participate in an online support community, how they interacted and made use of the online community, and how this knowledge could assist nursing in improving care for this growing population A six month sample of internet postings from an international transplant-related social media site was analyzed using an inductive qualitative content analysis adapted from Graneheim and Lundman (2003) within the theoretical lens of Unitary Caring Science (Smith, 1999) The study provided a unique perspective of how members used the social media support group The synthesis of four pandimensional interconnected patterns, expressing emotions, sharing experiences, exchanging information, and offering reciprocal support lead to a theme of being known and understood Healing transcendence emerged as a unitary transformative metatheme that reflected the holistic nature of the member interaction in the online support experience
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Date Issued: 2016
PURL: http://purl.flvc.org/fau/fd/FA00004768
Subject Headings: Transplantation of organs, tissues, etc--Social aspects, Mass media--Social aspects, Social media, Interpersonal relations, Self-help groups
Format: Document (PDF)

FAU Theses and Dissertations (11)	+ -
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HBOI Faculty Contributions (1)	+ -

Tissue Engineering (2)	+ -
Tissue Inhibitor of Metalloproteinases (2)	+ -
Beta-tricalcium phosphate (1)	+ -
Biocompatible Materials (1)	+ -
Bone Regeneration (1)	+ -

Bone and Bones (1)	+ -
Bone regeneration (1)	+ -
Breast--Cancer--Treatment (1)	+ -
Calcium Phosphates (1)	+ -
Caregivers (1)	+ -
Caring (1)	+ -
Chaetognatha (1)	+ -
Chitosan--Biotechnology. (1)	+ -
Chondroitin Sulfates (1)	+ -
Conduct of life (1)	+ -
Cryobiology (1)	+ -
Donation of organs, tissues, etc (1)	+ -
Donation of organs, tissues, etc. (1)	+ -
Drug Delivery Systems (1)	+ -
Emergency medical personnel (1)	+ -
Family relationships (1)	+ -
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Genetic Engineering --methods (1)	+ -
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Interpersonal relations (1)	+ -
Mass media--Social aspects (1)	+ -
Metalloproteinases --Inhibitors --Therapeutic use (1)	+ -
Newborn infants (1)	+ -
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article (2)	+ -

Florida Atlantic University (10)	+ -
College of Engineering and Computer Science (4)	+ -
Department of Ocean and Mechanical Engineering (4)	+ -
Kang, Yunqing (4)	+ -
Christine E. Lynn College of Nursing (3)	+ -

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