Current Search: Sponges--Caribbean Sea (x)
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Title
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Biochemical and morphologicalheterogeneity in the Caribbean sponge Xestospongia muta (petrosida: Petrosiidae).
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Creator
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Kerr, Russell G., Kelly-Borges, M., Harbor Branch Oceanographic Institute
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Date Issued
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1994
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PURL
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http://purl.flvc.org/fau/fd/FA00007380
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Subject Headings
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Sponges--Caribbean Sea, Morphology, Biochemistry, Sterols
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Format
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Document (PDF)
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Title
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Isospongiadiol, a cytotoxic and antiviral diterpene from a Caribbean deep water marine sponge, Spongia sp.
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Creator
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Kohmoto, S., McConnell, O. J., Wright, Amy E., Cross, S. S.
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Date Issued
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1987
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PURL
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http://purl.flvc.org/FCLA/DT/3343811
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Subject Headings
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Sponges--Caribbean Sea, Diterpenes, Antiviral agents
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Format
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Document (PDF)
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Title
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Climate change impacts on the secondary metabolite production in Caribbean coral reef sponges.
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Creator
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Vansach, Tifanie, Duckworth, Alan R., Hard, M., Stubler, A., West, Lyndon, Graduate College
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Date Issued
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2011-04-08
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PURL
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http://purl.flvc.org/fcla/dt/3164802
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Subject Headings
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Climatic changes --Environmental aspects, Metabolism, Sponges --Caribbean Sea
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Format
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Document (PDF)
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Title
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Topsentin, bromotopsentin, and dihydrodeoxybromotopsentin; antiviral and antitumor bis(indolyl)imidazoles from Caribbean deep-sea sponges of the family Halichondriidae. Structural and synthetic studies.
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Creator
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Tsujii, S., Rinehart, Kenneth L., Gunasekera, Sarath P., Kashman, Y., Cross, S. S., Lui, M. S., Pomponi, Shirley A., Diaz, Maria Cristina
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Date Issued
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1988
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PURL
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http://purl.flvc.org/FCLA/DT/3332952
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Subject Headings
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Sponges--Caribbean Sea, Imidazoles, Indoles, Antiviral agents, Antineoplastic agents
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Format
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Document (PDF)
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Title
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Selective cytotoxic activity of the marine derivedbatzelline compounds against pancreatic cancer cell lines.
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Creator
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Guzman, Esther A., Johnson, J. D., Carrier, M. K., Meyer, C. I., Pitts, Tara P., Gunasekera, Sarath P., Wright, Amy E.
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Date Issued
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2009
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PURL
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http://purl.flvc.org/fau/fd/FA00007114
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Subject Headings
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Pancreas--Cancer, Marine natural products, Drug Discovery, Sponges--Caribbean Sea, Mechanism of action (Biochemistry)
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Format
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Document (PDF)
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Title
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6-Hydroxydiscodermindole, A New Discodermindole from the Marine Sponge Discodermia polydiscus.
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Creator
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Cohen, Jesse, Paul, Gopal K., Gunasekera, Sarath P., Longley, Ross E., Pomponi, Shirley A.
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Date Issued
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2004
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PURL
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http://purl.flvc.org/FCLA/DT/2796025
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Subject Headings
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Antibody-dependent cell cytotoxicity, Calcarea, Demospongiae, Sponges --Caribbean Sea, Sponges --Cytology
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Format
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Document (PDF)
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Title
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Secobatzellines A and B, two new enzyme inhibitors from a deep-water Caribbean sponge of the genus Batzella.
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Creator
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Gunasekera, Sarath P., McCarthy, Peter J., Longley, Ross E., Pomponi, Shirley A., Wright, Amy E.
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Date Issued
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1999
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PURL
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http://purl.flvc.org/FCLA/DT/3172682
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Subject Headings
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Sponges --Caribbean Sea, Marine natural products, Toxicity testing --In vitro, Phosphatases, Peptidase
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Format
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Document (PDF)
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Title
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Chemical Studies of Caribbean Marine Organisms.
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Creator
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Vansach, Tifanie, West, Lyndon M., Florida Atlantic University, Charles E. Schmidt College of Science, Department of Chemistry and Biochemistry
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Abstract/Description
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The projects described in this dissertation concentrated on investigating Caribbean species for qualitative and quantitative chemical differences. Chapter one includes a brief update on the status of natural products as drugs, a discussion of the biodiversity of Caribbean marine organisms as well as a discussion about the chemistry of algae and sponges. In chapter two, an experiment to test for possible effects of warmer, more acidic water and how that will impact coral reef organisms was...
Show moreThe projects described in this dissertation concentrated on investigating Caribbean species for qualitative and quantitative chemical differences. Chapter one includes a brief update on the status of natural products as drugs, a discussion of the biodiversity of Caribbean marine organisms as well as a discussion about the chemistry of algae and sponges. In chapter two, an experiment to test for possible effects of warmer, more acidic water and how that will impact coral reef organisms was conducted. Six common Caribbean coral reef sponge species were grown in seawater for 24 days ranging from values experienced at summer-maxima (temperature = 28 ºC; pH = 8.1) to those predicted for the year 2100 (T = 31 ºC; pH = 7.8). For each species, attachment rates, growth, and survival were similar between temperature and pH levels. Only two metabolite concentrations varied significantly between treatments but were similar to baseline levels. In chapter three, a chemical survey of Florida Keys algae was performed using MeOH extraction and HP-20 SPE with varying Me2CO:H2O solutions. 1H NMR spectra were collected for each fraction and analyzed for interesting signals. A Laurencia sp. was extracted and found to contain the known compound isodactylyne (61) with the structure determined using spectroscopic analyses. In chapter four, a Laurencia obtusa specimen was investigated to determine the compound causing oxygenated signals between 4.50 – 4.80 ppm in the 1H NMR spectra observed in chapter three. A large scale extraction and fractionation was performed and the compound was determined to be 1-O-palmitoyl-2-O-myristoyl-3-O-(6-sulfo-α- D-quinovo-pyranosyl)-glycerol (63). In chapter five, the isolation and structural elucidation of a new compound, furocaespitanenone (64) and two known compounds (10R)- and (10S)-10-O-methylfurocaespitanelactol 65 and 66, from a Laurencia sp. collected off of the Florida Keys using MeOH extraction and HP-20 column chromatography is described. A potential biosynthesis of 64 from furocaepsitane (68) is proposed.
Show less
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Date Issued
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2019
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PURL
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http://purl.flvc.org/fau/fd/FA00013274
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Subject Headings
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Marine organisms, Caribbean, Algae--chemistry, Sponges--Caribbean Sea, Chemistry
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Format
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Document (PDF)
