Current Search: Rats--Physiology (x)
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- Title
- REVERSAL OF FORELIMB PLACING DEFICITS WITH CORTICAL SPREADING DEPRESSION.
- Creator
- Kehoe, Priscilla, Florida Atlantic University, Wolgin, David L., Charles E. Schmidt College of Science, Department of Psychology
- Abstract/Description
-
Rats with lesions of the ventromedial aspect of the internal capsule in the vicinty of the entopeduncular nucleus (EP) showed a loss of forelimb placing (chin, contact and visual) in the contralateral limb. Spreading depression induced by instillation of KCl (25%) to the cortex contralateral to the lesion brought back placing in the affected limb and abolished placing in the normal limb. Within 24 hours the pre-spreading depression state returned and the impaired limb no longer placed while...
Show moreRats with lesions of the ventromedial aspect of the internal capsule in the vicinty of the entopeduncular nucleus (EP) showed a loss of forelimb placing (chin, contact and visual) in the contralateral limb. Spreading depression induced by instillation of KCl (25%) to the cortex contralateral to the lesion brought back placing in the affected limb and abolished placing in the normal limb. Within 24 hours the pre-spreading depression state returned and the impaired limb no longer placed while the normal limb recovered function. In contrast, KCl on the ipsilateral cortex did not reinstate placing. These results suggest that the loss of placing following lesions of the EP are due to tonic inhibition from the cortex contralateral to the lesion. Sensory summation was evident during the early recovery period when placing was accomplished only if two kinds of stimuli were provided simultaneously. Forelimb placing recovered to its pre-lesion state.
Show less - Date Issued
- 1981
- PURL
- http://purl.flvc.org/fcla/dt/14078
- Subject Headings
- Rats--Physiology, Neural circuitry
- Format
- Document (PDF)
- Title
- Effects of Target Neuron Loss on Olfactory Receptor Neurons in the Adult Rat.
- Creator
- Sultan, Krista K., Guthrie, Kathleen M., Florida Atlantic University
- Abstract/Description
-
Unlike most neurons in the adult nervous system, olfactory receptor neurons (ORN), found in the olfactory epithelium (OE), continually turnover in the adult rat. These neurons project their axons to the olfactory bulb which is their central target. The present study eliminated target neurons in the bulb using N-methyl-D-aspartate (NMDA) to examine the effects of target loss on ORN survival and maturation. We compared the effects of the NMDA lesion to bulbectomy, a permanent surgical removal...
Show moreUnlike most neurons in the adult nervous system, olfactory receptor neurons (ORN), found in the olfactory epithelium (OE), continually turnover in the adult rat. These neurons project their axons to the olfactory bulb which is their central target. The present study eliminated target neurons in the bulb using N-methyl-D-aspartate (NMDA) to examine the effects of target loss on ORN survival and maturation. We compared the effects of the NMDA lesion to bulbectomy, a permanent surgical removal of the bulb, which simultaneously causes damage to ORN axons. We found that unlike bulbectomy, large numbers of dying OE cells were not observed at any time after the lesion. The number of immature neurons increased relative to the control side, and the number of mature neurons also slightly increased with time following NMDA lesion. Survival of ORNs does not seem to be significantly altered in the absence of its target.
Show less - Date Issued
- 2007
- PURL
- http://purl.flvc.org/fau/fd/FA00000838
- Subject Headings
- Rats--Physiology, Neurophysiology, Apoptosis, Regeneration (Biology)
- Format
- Document (PDF)
- Title
- OLFACTORY CONTRIBUTIONS TO THE INGESTIVE BEHAVIOR OF INFANT RATS: EFFECTS OF OLFACTORY AND VOMERONASAL DEAFFERENTATION (DEVELOPMENT, FEEDING).
- Creator
- TERRY, LESLIE MARY., Florida Atlantic University
- Abstract/Description
-
This research was designed to assess the extent to which olfactory cues, both main olfactory and vomeronasal, are important in the expression of independent ingestion in 6-day-old rat pups. Independent ingestion in young rat pups involves the intake of large volumes of milk (delivered throught an intraoral cannula) and is accompanied by dramatic behavioral activation. It was found that behavioral activation in response to milk infusions or milk odor was eliminated in pups deprived of main...
Show moreThis research was designed to assess the extent to which olfactory cues, both main olfactory and vomeronasal, are important in the expression of independent ingestion in 6-day-old rat pups. Independent ingestion in young rat pups involves the intake of large volumes of milk (delivered throught an intraoral cannula) and is accompanied by dramatic behavioral activation. It was found that behavioral activation in response to milk infusions or milk odor was eliminated in pups deprived of main olfactory input (by nasal lavage with ZnS04), or vomeronasal input (by vomeronasal nerve sections). Similarly, after vomeronasal deafferentation and ZnS04 lavage pups cease to probe and become active in response to milk infusions and milk odor accompanied by water infusions. The results suggest that behavioral activation may be mediated in a similar fashion by both the main and vomeronasal olfactory system.
Show less - Date Issued
- 1985
- PURL
- http://purl.flvc.org/fcla/dt/14257
- Subject Headings
- Rats--Behavior--Experiments, Rats--Development, Rats--Physiology, Olfactometry
- Format
- Document (PDF)