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Title: Bioactivity of marine organisms: relationships with taxonomy, geography and depth.
Creator: Reed, John K., Sennett, Susan H., McCarthy, Peter J., Pitts, Tara P., Wright, Amy E., Pomponi, Shirley A.
Date Issued: 1998
PURL: http://purl.flvc.org/fau/fd/FA00007421
Subject Headings: Marine organisms, Bioactive compounds, Marine natural products
Format: Document (PDF)

Title: Marine organisms as a source of novel lead structures for drug development.
Creator: Wright, Amy E.
Date Issued: 2000
PURL: http://purl.flvc.org/fau/fd/FA00007060
Subject Headings: Marine organisms, Marine natural products, Drug development
Format: Document (PDF)

Title: The many faces of gene expression profiling: transcriptome analyses applied towardselucidating marine organismal interactions and metabolism.
Creator: Lopez, Jose V., Mouzon, B., McCarthy, Peter J., Kerr, Russell G.
Date Issued: 2009
PURL: http://purl.flvc.org/fau/fd/FA00007286
Subject Headings: Gene expression, Transcriptome, Molecular biotechnology, Marine ecology, Marine organisms
Format: Document (PDF)

Title: Patterns of stimulated bioluminescence in two pyrosomes (Tunicata: Pyrosomatidae).
Creator: Bowlby, Mark R., Widder, Edith A., Case, J. F., Harbor Branch Oceanographic Institute
Date Issued: 1990
PURL: http://purl.flvc.org/FCLA/DT/3171565
Subject Headings: Bioluminescence, Luminescence --Research, Pyrosoma, Tunicata, Marine organisms
Format: Document (PDF)

Title: Non-conventional techniques for sampling and collecting marine organisms.
Creator: Tusting, Robert F., Harbor Branch Oceanographic Institute
Date Issued: 1986
PURL: http://purl.flvc.org/FCLA/DT/3338500
Subject Headings: Sampling, Marine organisms, Sampling--Technique
Format: Document (PDF)

Title: A SEASONAL STUDY OF SESSILE MARINE FOULING ORGANISMS IN NORTHERN LAKE WORTH, FLORIDA.
Creator: BANE, LENI LORENZ., Florida Atlantic University, Marsh, G. Alex
Abstract/Description: Seasonal settling patterns and community development of the fouling complex on gelcoat-covered fiber glass plates (103.22 cm2 ) were observed from September 1976 to September 1977 at three stations in northern Lake Worth, Florida. Percent coverage for each species was estimated using 60 points randomly positioned over the plate area. Physico-chemical conditions at stations 1 and 2 were relatively stable, whereas station 3 was subjected to wide variations in salinity and, to a lesser extent,...
Show moreSeasonal settling patterns and community development of the fouling complex on gelcoat-covered fiber glass plates (103.22 cm2 ) were observed from September 1976 to September 1977 at three stations in northern Lake Worth, Florida. Percent coverage for each species was estimated using 60 points randomly positioned over the plate area. Physico-chemical conditions at stations 1 and 2 were relatively stable, whereas station 3 was subjected to wide variations in salinity and, to a lesser extent, dissolved oxygen. Plates at stations 1 and 2 consistently collected more species than those at station 3. Peak settling and growth at all stations occurred in the spring and early summer. Three species settled only on plates that had been previously colonized. Even though gelcoat-covered fiber glass was designed to discourage fouling, it proved to be a satisfactory substrate for a thriving community.
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Date Issued: 1979
PURL: http://purl.flvc.org/fcla/dt/13981
Subject Headings: Fouling organisms, Marine fouling organisms--Florida--Lake Worth
Format: Document (PDF)

Title: Case Study: marine mammals as sentinel speciesfor oceans and human health.
Creator: Bossart, Gregory D., Harbor Branch Oceanographic Institute
Date Issued: 2006
PURL: http://purl.flvc.org/fau/fd/FA00007157
Subject Headings: Marine mammals, Sentinel organisms, Indicators (Biology), Health, Ocean
Format: Document (PDF)

Title: A molecular systematic survey of cultured microbial associates of deep-water marine invertebrates.
Creator: Sfanos, Karen S., Harmody, Dedra K., Dang, Phat, Ledger, Angela, Pomponi, Shirley A., McCarthy, Peter J., Lopez, Jose V.
Date Issued: 2004
PURL: http://purl.flvc.org/FCLA/DT/2827820
Subject Headings: Molecular microbiology, Microbial ecology, Marine organisms, Microorganisms, Sponges
Format: Document (PDF)

Title: Effects of disturbance and initial settlement on fouling community structure.
Creator: Mook, David H., Harbor Branch Oceanographic Institute
Date Issued: 1981
PURL: http://purl.flvc.org/FCLA/DT/3174986
Subject Headings: Fouling, Marine fouling organisms, Indian River (Fla. : Lagoon)
Format: Document (PDF)

Title: REDOX ENVIRONMENT CONTROLS ON THE DEGRADATION OF HARMFUL ORGANIC CONTAMINANTS IN MARINE SEDIMENT.
Creator: Quinan, Matthew P., Beckler, Jordon, Florida Atlantic University, Department of Marine Science and Oceanography, Charles E. Schmidt College of Science
Abstract/Description: Harmful organic contaminants, such as petroleum hydrocarbons, are ubiquitous in coastal marine ecosystems around the world, a problem that will only be exacerbated with rising sea level and increased inundation of coastal urban areas. Therefore, it is necessary to understand the fate of these contaminants following their deposition on marine sediment, where they can potentially persist for long periods of time. As organic carbon remineralization rates depend on the respiration process...
Show moreHarmful organic contaminants, such as petroleum hydrocarbons, are ubiquitous in coastal marine ecosystems around the world, a problem that will only be exacerbated with rising sea level and increased inundation of coastal urban areas. Therefore, it is necessary to understand the fate of these contaminants following their deposition on marine sediment, where they can potentially persist for long periods of time. As organic carbon remineralization rates depend on the respiration process employed by the bacteria in the sediment, it was the goal of this study to determine how the sediment redox environment, with an emphasis on Fe redox chemistry, affects the biodegradation of recalcitrant petroleum hydrocarbon compounds. While amendment of natural sediment with Fe minerals that are commonly transported to coastal areas following erosion from continental crust did successfully catalyze Fe reduction and inhibit sulfate reduction, the effect on the hydrocarbon biodegradation rate was negligible. However, inoculation of the sediment with Shewanella oneidensis, an exoelectrogenic, Fe reducing bacteria known to catalyze the degradation of hydrocarbon compounds found in crude oil, did significantly affect the redox environment and sediment microbial communities and alter the pattern of hydrocarbon loss in the sediment over time.
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Date Issued: 2021
PURL: http://purl.flvc.org/fau/fd/FA00013801
Subject Headings: Marine sediments, Coastal sediments, Organic compounds--Biodegradation, Oil spills
Format: Document (PDF)

Title: Maximizing the potential of marine organism collections for both pharmacological and systematic studies.
Creator: Pomponi, Shirley A.
Date Issued: 1989
PURL: http://purl.flvc.org/fau/fd/FA00007194
Subject Headings: Marine organisms, Marine natural products, Pharmacology, Johnson-Sea-Link II (Submarine), Submersibles
Format: Document (PDF)

Title: An extraction optimization and determination of the absolute configuartion of clathric acid.
Creator: Rueda de Leon, Rolando, Charles E. Schmidt College of Science, Department of Chemistry and Biochemistry
Abstract/Description: Current research in natural products has heavily focused on the identification of potent biologically active compounds, specifically for drug development. The project detailed in this thesis focuses on the extraction of compounds from marine invertebrates as well as defining the absolute configuration for a compound. Utilizing marine invertebrates, the sonications method developed in this thesis provides an alternative approach to rapidly extract compounds for primary screening. This method...
Show moreCurrent research in natural products has heavily focused on the identification of potent biologically active compounds, specifically for drug development. The project detailed in this thesis focuses on the extraction of compounds from marine invertebrates as well as defining the absolute configuration for a compound. Utilizing marine invertebrates, the sonications method developed in this thesis provides an alternative approach to rapidly extract compounds for primary screening. This method is viable compared to a traditional overnight extraction method, without suffering compound degredation... Previously, clathric acid was isolated from an unknown Clathria sp. This compound is a bibyblic C-21 terpenoid shown to have mild antimicrobial activity against gram positive bacteria. With only its relative configuration established, additional amounts of clathric acid were required to define the overall absolute configuration. Identifying the Clathria sp. to be Clathria compressa, through spicule analysis, additional sponge tissues were then collected off the coast of Boca Raton, Florida to isolate additional quatities of clathric acid. The absolulte configuration was determined through circular dichroism and the octant rule to establish a final configuration for clathric acid's four carbon stereocenters to be: (3S, 7S, 8R, and 12S).
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Date Issued: 2012
PURL: http://purl.flvc.org/FAU/3355874
Subject Headings: Organic compounds, Analysis, Extraction (Chemistry), Natural products, Therapeutic use, Marine biotechology, Marine resources, Research, Sponges, Ecology
Format: Document (PDF)

Title: Isolation of briareolate esters from Briareum asbestinum.
Creator: Meginley, Rian J., Charles E. Schmidt College of Science, Department of Chemistry and Biochemistry
Abstract/Description: The gorgonian Briareum asbestinum is widely studied because it possesses highly oxygenated novel structures, many of which exhibit useful biological activities. Recently, two new briarane diterpenoids, briareolate esters J and K, together with two known briareolate esters have been isolated from a specimen of Briareum asbestinum collected off the coast of Boca Raton, Florida. The method used was a 96-well plate real-time cell electronic sensing (RT-CES) system to discover compounds that...
Show moreThe gorgonian Briareum asbestinum is widely studied because it possesses highly oxygenated novel structures, many of which exhibit useful biological activities. Recently, two new briarane diterpenoids, briareolate esters J and K, together with two known briareolate esters have been isolated from a specimen of Briareum asbestinum collected off the coast of Boca Raton, Florida. The method used was a 96-well plate real-time cell electronic sensing (RT-CES) system to discover compounds that impact human embryonic stem cell growth. The compounds were isolated using reversed phase polystyrene divinylbenzene chromatographic support HP20ss followed by normal phased HPLC using a luna silica column. The structures of the compounds were established though the interpretation of spectroscopic data. Activity testing was conducted against hESCs (BG02) with briareolate ester J showing no inhibition activity and briareolate ester K showing mild activity with an EC50 value of 25 (So(BM. These results confirm that the exact confirmation and existence of the (E,Z)-dienone is related to the activity that was observed with the previously isolated briareolate esters L and M.
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Date Issued: 2013
PURL: http://purl.flvc.org/fcla/dt/3360959
Subject Headings: Coral reef ecology, Marine organisms, Environmental aspects, Marine natural products, Bioactive compounds
Format: Document (PDF)

$A novel vertebrate eye using both refractive and reflective optics$

Title: A novel vertebrate eye using both refractive and reflective optics.
Creator: Wagner, Hans-Joachim, Douglas, Ron H., Frank, Tamara M., Roberts, Nicholas W., Partridge, Julian C., Harbor Branch Oceanographic Institute
Date Issued: 2009-01-27
PURL: http://purl.flvc.org/FCLA/DT/1779078
Subject Headings: Eye, Eye --Anatomy, Eye --Movements --physiology, Fishes --Sense organs, Marine animals --Physiology, Vision --Physiology
Format: Document (PDF)

Title: Eastern Atlantic expedition: submersible and scuba collections for bioactive organisms from the Azores to Western Africa.
Creator: Reed, John K., Pomponi, Shirley A.
Date Issued: 1992
PURL: http://purl.flvc.org/fau/fd/FA00007305
Subject Headings: North Atlantic Ocean, Harbor Branch Oceanographic Institution, Benthos--Sampling, Marine organisms, Biomedical Research
Format: Document (PDF)

Title: Chemical Studies of Caribbean Marine Organisms.
Creator: Vansach, Tifanie, West, Lyndon M., Florida Atlantic University, Charles E. Schmidt College of Science, Department of Chemistry and Biochemistry
Abstract/Description: The projects described in this dissertation concentrated on investigating Caribbean species for qualitative and quantitative chemical differences. Chapter one includes a brief update on the status of natural products as drugs, a discussion of the biodiversity of Caribbean marine organisms as well as a discussion about the chemistry of algae and sponges. In chapter two, an experiment to test for possible effects of warmer, more acidic water and how that will impact coral reef organisms was...
Show moreThe projects described in this dissertation concentrated on investigating Caribbean species for qualitative and quantitative chemical differences. Chapter one includes a brief update on the status of natural products as drugs, a discussion of the biodiversity of Caribbean marine organisms as well as a discussion about the chemistry of algae and sponges. In chapter two, an experiment to test for possible effects of warmer, more acidic water and how that will impact coral reef organisms was conducted. Six common Caribbean coral reef sponge species were grown in seawater for 24 days ranging from values experienced at summer-maxima (temperature = 28 ºC; pH = 8.1) to those predicted for the year 2100 (T = 31 ºC; pH = 7.8). For each species, attachment rates, growth, and survival were similar between temperature and pH levels. Only two metabolite concentrations varied significantly between treatments but were similar to baseline levels. In chapter three, a chemical survey of Florida Keys algae was performed using MeOH extraction and HP-20 SPE with varying Me2CO:H2O solutions. 1H NMR spectra were collected for each fraction and analyzed for interesting signals. A Laurencia sp. was extracted and found to contain the known compound isodactylyne (61) with the structure determined using spectroscopic analyses. In chapter four, a Laurencia obtusa specimen was investigated to determine the compound causing oxygenated signals between 4.50 – 4.80 ppm in the 1H NMR spectra observed in chapter three. A large scale extraction and fractionation was performed and the compound was determined to be 1-O-palmitoyl-2-O-myristoyl-3-O-(6-sulfo-α- D-quinovo-pyranosyl)-glycerol (63). In chapter five, the isolation and structural elucidation of a new compound, furocaespitanenone (64) and two known compounds (10R)- and (10S)-10-O-methylfurocaespitanelactol 65 and 66, from a Laurencia sp. collected off of the Florida Keys using MeOH extraction and HP-20 column chromatography is described. A potential biosynthesis of 64 from furocaepsitane (68) is proposed.
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Date Issued: 2019
PURL: http://purl.flvc.org/fau/fd/FA00013274
Subject Headings: Marine organisms, Caribbean, Algae--chemistry, Sponges--Caribbean Sea, Chemistry
Format: Document (PDF)

Title: The chemistry of Briareum asbestinum.
Creator: Rondeau, Melody D., Charles E. Schmidt College of Science, Department of Chemistry and Biochemistry
Abstract/Description: Briareum asbestinum, a soft coral, is a rich source of diterpenoid natural products. The secondary metabolites of B. asbestinum fall into four classes : asbestinins, briarellins, briareolate esters, and briaranes. Briareolate esters have been shown to possess biological activity and were previously only reported from Tobago. Our group recently isolated briareolate esters from a specimen collected off the coast of Boca Raton, Florida. To determine whether location has an impact on the...
Show moreBriareum asbestinum, a soft coral, is a rich source of diterpenoid natural products. The secondary metabolites of B. asbestinum fall into four classes : asbestinins, briarellins, briareolate esters, and briaranes. Briareolate esters have been shown to possess biological activity and were previously only reported from Tobago. Our group recently isolated briareolate esters from a specimen collected off the coast of Boca Raton, Florida. To determine whether location has an impact on the chemistry produced by the organism, a method to discern between chemotypes was sought. Several techniques including thin layer chromatography (TLC), high performance liquid chromatography (HPLC), nuclear magnetic resonance (NMR), and sclerite analysis were employed, with NMR being the most successful method. By utilizing both 1H and COSY NMR experiments, it is possible to differentiate between the chemotypes of B. asbestinum. Application of this method allowed analysis of chemical variability with respect to location.
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Date Issued: 2012
PURL: http://purl.flvc.org/FAU/3355882
Subject Headings: Heterocyclic compounds, Synthesis, Coral reef ecology, Marine organisms, Environmental aspects, Biochemical markers
Format: Document (PDF)

HBOI Faculty Contributions (11)	+ -
FAU Theses and Dissertations (6)	+ -

Marine organisms (11)	+ -
Marine natural products (4)	+ -
Bioactive compounds (2)	+ -
Coral reef ecology (2)	+ -
Environmental aspects (2)	+ -

Sponges (2)	+ -
Algae--chemistry (1)	+ -
Analysis (1)	+ -
Benthos--Sampling (1)	+ -
Biochemical markers (1)	+ -
Bioluminescence (1)	+ -
Biomedical Research (1)	+ -
Caribbean (1)	+ -
Chemistry (1)	+ -
Coastal sediments (1)	+ -
Drug development (1)	+ -
Ecology (1)	+ -
Extraction (Chemistry) (1)	+ -
Eye (1)	+ -
Eye --Anatomy (1)	+ -
Eye --Movements --physiology (1)	+ -
Fishes --Sense organs (1)	+ -
Fouling (1)	+ -
Fouling organisms (1)	+ -
Gene expression (1)	+ -
Harbor Branch Oceanographic Institution (1)	+ -
Health (1)	+ -
Heterocyclic compounds (1)	+ -
Indian River (Fla. : Lagoon) (1)	+ -
Indicators (Biology) (1)	+ -

article (11)	+ -
Electronic Thesis or Dissertation (6)	+ -

Charles E. Schmidt College of Science (5)	+ -
Harbor Branch Oceanographic Institute (5)	+ -
Department of Chemistry and Biochemistry (4)	+ -
Pomponi, Shirley A. (4)	+ -
Florida Atlantic University (3)	+ -

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