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Title: Insulin-dependent diabetes mellitus and cognitive dysfunction.
Creator: Nash, Stacey S., Florida Atlantic University, Bressler, Steven L., Kersten, Alan
Abstract/Description: Insulin-dependent diabetes mellitus (IDDM) is a metabolic disorder arising from pancreatic dysfunction. For survival, a diabetic must rely upon an exogenous source of insulin to ensure cellular health. Hypoglycemia is a condition that may arise in IDDM patients in which more insulin than glucose is present in the body. Chronic, severe occurrences of this condition have been speculated to incur memory impairment in diabetics. This experiment sought to determine if diabetics performed...
Show moreInsulin-dependent diabetes mellitus (IDDM) is a metabolic disorder arising from pancreatic dysfunction. For survival, a diabetic must rely upon an exogenous source of insulin to ensure cellular health. Hypoglycemia is a condition that may arise in IDDM patients in which more insulin than glucose is present in the body. Chronic, severe occurrences of this condition have been speculated to incur memory impairment in diabetics. This experiment sought to determine if diabetics performed differently from a non-diabetic population on a delayed matching memory task, and also if those diabetics experiencing hypoglycemia performed more poorly than other diabetics on this task. It was found that IDDM patients do not perform differently from non-diabetics on a matching task, and most diabetics did not perform more poorly than other patients on the same task. One diabetic experiencing severe, chronic hypoglycemia performed more poorly than other experiment participants, suggesting that hypoglycemia may, in fact, be related to memory impairment on this delayed matching task.
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Date Issued: 2002
PURL: http://purl.flvc.org/fcla/dt/12922
Subject Headings: Diabetes, Hypoglycemia, Cognition disorders
Format: Document (PDF)

Title: Self-care agency in adults with diabetes mellitus.
Creator: Thompson, Marybeth Eleanor., Florida Atlantic University, Freeman, Edward
Abstract/Description: Diabetes Mellitus is a chronic illness which provides numerous and varied self-care challenges to those individuals seeking to avoid or delay complications. The purpose of this study is to determine the self-care agency, as defined by Orem, of sample of 100 adults diagnosed with non-insulin dependant diabetes mellitus. Self-care agency was measured by the Self-As-Carer Inventory, a 40-item questionnaire, and a descriptive, cross-sectional design was utilized to structure the study.
Date Issued: 1997
PURL: http://purl.flvc.org/fcla/dt/15524
Subject Headings: Non-insulin-dependent diabetes, Diabetics, Self-care, Health
Format: Document (PDF)

Title: Exploring the relationship of social factor and diabetes risk by zip codes among adults in Palm Beach County.
Creator: Hutton, Ted, Millender, Eugenia
Date Issued: 2013-04-05
PURL: http://purl.flvc.org/fcla/dt/3361095
Subject Headings: Diabetes--Social aspects, Diabetes--Risk factors, Diabetes--Prevention
Format: Document (PDF)

Title: Female type I diabetics with eating disorders: Purging by insulin withholding.
Creator: Reilly, Maureen Bridget., Florida Atlantic University, Locsin, Rozzano
Abstract/Description: This study provides descriptions of experiences and characteristics of female type I diabetics with eating disorders who purge by insulin withholding. The multiple case study design was used as adapted from Yin. Four female type I diabetics with eating disorders who purge by insulin withholding were interviewed using a semi-structured interview guide. From these interviews, common themes emerged which described the experiences and characteristics of the participants. These themes were...
Show moreThis study provides descriptions of experiences and characteristics of female type I diabetics with eating disorders who purge by insulin withholding. The multiple case study design was used as adapted from Yin. Four female type I diabetics with eating disorders who purge by insulin withholding were interviewed using a semi-structured interview guide. From these interviews, common themes emerged which described the experiences and characteristics of the participants. These themes were supported by answers to questions in the ATT 39 questionnaire. Themes which emerged are: self-care deficits, anger, shame, secretiveness, guilt, hopelessness, uniqueness, depression, low self esteem, control issues, depression, and body image distortion. These themes provided contextual relevance to participants' lived experiences, interconnected dual diagnoses and the ambivalence of recovering from their eating disorder. Implications for nursing education, practice, and research are discussed.
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Date Issued: 1997
PURL: http://purl.flvc.org/fcla/dt/15467
Subject Headings: Diabetes, Insulin, Women--Diseases, Appetite disorders
Format: Document (PDF)

Title: Do The Dynamics of Insulin Delivery Matter for Management of Diabetes Mellitus? Evidence From Molecular Measures in a Diabetic Rat Model.
Creator: Reis, Danielle, Tuller, Betty, Florida Atlantic University
Abstract/Description: The current study uses a diabetic rat model to measure the effects of pulsatile versus continuous insulin delivery on IRS-2 in the liver. The purpose is to determine if pulsatile, compared with continuous, insulin delivery leads to reduced insulin resistance in diabetic rats. Insulin signaling in the liver is mediated primarily through IRS-2 and tissue responsiveness to insulin may be detected by monitoring the lRS-2 signaling pathway. Western blots were performed to measure IRS-2 protein...
Show moreThe current study uses a diabetic rat model to measure the effects of pulsatile versus continuous insulin delivery on IRS-2 in the liver. The purpose is to determine if pulsatile, compared with continuous, insulin delivery leads to reduced insulin resistance in diabetic rats. Insulin signaling in the liver is mediated primarily through IRS-2 and tissue responsiveness to insulin may be detected by monitoring the lRS-2 signaling pathway. Western blots were performed to measure IRS-2 protein levels for each delivery condition and treatment day. Results revealed that overall, the pulsatile insulin delivery method showed a significant increase in IRS-2 levels over the continuous insulin delivery method by treatment day 5. These findings imply that the pulsatile delivery method, over a period of time, triggers more insulin receptor action. Conversely, the results of the continuous delivery system show a decrease in IRS-2 levels as the number of doses of insulin increased.
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Date Issued: 2007
PURL: http://purl.flvc.org/fau/fd/FA00000818
Subject Headings: Diabetes--Treatment, Rats as laboratory animals, Insulin--Receptors
Format: Document (PDF)

Title: A study on glucose metabolism: Computer simulation and modeling.
Creator: Leesirikul, Meta., Florida Atlantic University, Neelakanta, Perambur S., Roth, Zvi S., Morgera, Salvatore D., College of Engineering and Computer Science, Department of Computer and Electrical Engineering and Computer Science
Abstract/Description: Sorensen's model of glucose metabolism and regulation is reconstructed using SimulinkRTM. Most of the existing glucose metabolism models consist of several mass balance equations that interact with each others. Graphical format used by SimulinkRTM provides a visualized perspective of such relations so that it is easier to modify the model on ad hoc basis. Type-I and Type-II diabetes with relevant clinical details are simulated. Further, a control strategy is introduced in order to simulate...
Show moreSorensen's model of glucose metabolism and regulation is reconstructed using SimulinkRTM. Most of the existing glucose metabolism models consist of several mass balance equations that interact with each others. Graphical format used by SimulinkRTM provides a visualized perspective of such relations so that it is easier to modify the model on ad hoc basis. Type-I and Type-II diabetes with relevant clinical details are simulated. Further, a control strategy is introduced in order to simulate the control of exogenous insulin pump. Simulated results are consistent with available clinical data. Living systems in general, exhibit both stochastical and deterministic characteristics. Activities such as glucose metabolism traditionally modeled do not include stochastical properties, nor that they are viewed in the large framework of complex system with explicit interaction details. Currently, a complexity system model is developed to describe the glucose metabolism related activities. The simulation results obtained thereof illustrate the bounding domain of variations in some clinically observed details.
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Date Issued: 2005
PURL: http://purl.flvc.org/fcla/dt/13254
Subject Headings: Glucose--Metabolism, Computer simulation, Diabetes--Metabolism, Computer modeling
Format: Document (PDF)

Title: The Association Between Informal Caregiver Knowledge about Type 2 Diabetes Mellitus and Patients’ HbA1C Level among a Saudi Arabian Cohort.
Creator: Fallatah, Jamilah Ahmed, Wiese, Lisa Kirk, Florida Atlantic University, Christine E. Lynn College of Nursing, Christine E. Lynn College of Nursing
Abstract/Description: Background: Almost seven million persons in Saudi Arabia are diagnosed with Type 2 Diabetes Mellitus (T2DM). Lack of knowledge regarding T2DM among Saudi caregivers may impact T2DM management and disease outcomes, yet established educational programs for their caregivers are scant. There is a need to discover T2DM informal caregivers’ knowledge and its relation to patients' T2DM management, prior to designing educational interventions. Purpose: The purpose of this quantitative, correlational...
Show moreBackground: Almost seven million persons in Saudi Arabia are diagnosed with Type 2 Diabetes Mellitus (T2DM). Lack of knowledge regarding T2DM among Saudi caregivers may impact T2DM management and disease outcomes, yet established educational programs for their caregivers are scant. There is a need to discover T2DM informal caregivers’ knowledge and its relation to patients' T2DM management, prior to designing educational interventions. Purpose: The purpose of this quantitative, correlational study was to measure disease knowledge among informal caregivers for patients with T2DM in Saudi Arabia, and to compare findings to the patient-health status presented by HbA1C level. This study was conceptualized within nursing caring science, using Nursing as Caring Theory (Boykin & Schoenhofer, 2001), and the Individual and Family Self-Management Theory (Ryan & Sawin, 2009).
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Date Issued: 2023
PURL: http://purl.flvc.org/fau/fd/FA00014307
Subject Headings: Diabetes Mellitus, Type 2, Caregivers, Saudi Arabia, Nursing
Format: Document (PDF)

Title: Mixed Method of Health Literacy and Diabetes Self- Management Among Saudi Adults with Type 2 Diabetes Mellitus.
Creator: Almashni, Ibtisam Y., Hain, Debra, Florida Atlantic University, Christine E. Lynn College of Nursing, Christine E. Lynn College of Nursing
Abstract/Description: The worldwide threat of Diabetes Mellitus (DM) has been increasing rapidly, and is now an estimated 463 million, of which 55 million people originate from Middle East and Nort African (“MENA”) region (international Diabetes Federation [“IDF’], 2020). In Saudi Arabia, the prevalence of diabetes has roughly reached a ten-fold increase in the past three decades, placing Saudi Arabia’s incidence as one of the highest globally (Almubark et al., 2022). The purpose of the study was to examine the...
Show moreThe worldwide threat of Diabetes Mellitus (DM) has been increasing rapidly, and is now an estimated 463 million, of which 55 million people originate from Middle East and Nort African (“MENA”) region (international Diabetes Federation [“IDF’], 2020). In Saudi Arabia, the prevalence of diabetes has roughly reached a ten-fold increase in the past three decades, placing Saudi Arabia’s incidence as one of the highest globally (Almubark et al., 2022). The purpose of the study was to examine the relationship between health and diabetes self-management among Saudi adults with Type 2 Diabetes Mellitus (T2DM). The study further aimed to explore how Saudi adult with T2DM seek and utilize diabetes knowledge to self-manage their diabetes. The study was guided by Leininger’s Culture Care Diversity and Universality Theory (2002). Leininger’s Sunrise Enabler- Model provided a framework to explore the various factors that affect diabetes self-management through a cultural lens. This model provides a comprehensive understanding pf multiple factors influencing diabetes self-management. A sample of 66 Saudi adults with T2DM aged 40-61 and older was recruited from diabetes center and Primary Healthcare Center (PHCC) at National Guard Hospital King Abdulaziz Medical City Jeddah, Saudi Arabia. A Parallel Mixed Method (PPM) design was applied, using semi-structured interviews, Diabetes Self-management Questionnaire (DSMQ), Short Test of Functional Health Literacy in Adult (S-TOFHLA), and sociodemographic surveys.
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Date Issued: 2023
PURL: http://purl.flvc.org/fau/fd/FA00014326
Subject Headings: Diabetes, Health literacy, Self Management, Saudi Arabians, Health education
Format: Document (PDF)

Title: USE OF COMPLEMENTARY THERAPIES FOR DIABETES MELLITUS BY JAMAICAN ADULTS IN SOUTH FLORIDA: A FOCUSED ETHNOGRAPHY.
Creator: Brown, Raquel, Chiang-Hanisco, Lenny, Florida Atlantic University, Christine E. Lynn College of Nursing
Abstract/Description: Jamaicans, the largest group of English-speaking Caribbean people living in the United States (US), have a history of using bush medicine/complementary therapies (CT) in diabetes management. However, no research described the emic views of Jamaican adults regarding how they select the bush medicine they use or how they know these are suitable to manage diabetes. The purpose of this focused ethnography was to explore and describe how Jamaican adults with diabetes mellitus who live in South...
Show moreJamaicans, the largest group of English-speaking Caribbean people living in the United States (US), have a history of using bush medicine/complementary therapies (CT) in diabetes management. However, no research described the emic views of Jamaican adults regarding how they select the bush medicine they use or how they know these are suitable to manage diabetes. The purpose of this focused ethnography was to explore and describe how Jamaican adults with diabetes mellitus who live in South Florida select and use complementary therapies for managing their diabetes. The objectives were to: (1) Explore the emic views of Jamaican adults about using CT to manage diabetes mellitus; (2) Describe the rationale given by Jamaicans adults for using CT to manage diabetes mellitus; (3) Analyze and synthesize the data gathered about use of CT for diabetes by Jamaican adults to see if their actions have cultural components that can serve as a basis for providing culturally competent care.
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Date Issued: 2019
PURL: http://purl.flvc.org/fau/fd/FA00013287
Subject Headings: Diabetes--Alternative treatment, Jamaicans, Complementary Therapies, Ethnography, Culturally Competent Care--ethnology
Format: Document (PDF)

Title: Hypoxia-regulated glial cell-specific gene therapy to treat retinal neovascularization.
Creator: Biswal, Manas Ranjan., Charles E. Schmidt College of Science, Center for Complex Systems and Brain Sciences
Abstract/Description: Diabetic retinopathy is an ischemic retinal neovascular disease causing vision loss among adults. The studies presented involve the design and testing of a gene therapy vector to inhibit retinal revascularization, similar to that found in diabetic retinopathy. Gene therapy has proven to be an effective method to introduce therapeutic proteins to treat retinal diseases. Targeting a specific cell type and expression of therapeutic proteins according to the tissue microenvironment should have an...
Show moreDiabetic retinopathy is an ischemic retinal neovascular disease causing vision loss among adults. The studies presented involve the design and testing of a gene therapy vector to inhibit retinal revascularization, similar to that found in diabetic retinopathy. Gene therapy has proven to be an effective method to introduce therapeutic proteins to treat retinal diseases. Targeting a specific cell type and expression of therapeutic proteins according to the tissue microenvironment should have an advantage over traditional gene therapy by avoiding unwanted transgene expression. Hypoxia plays a significant role in the pathophysiology of many retinal ischemic diseases. Retinal Mèuller cells provide structural and functional support to retinal neurons, as well as playing a significant role in retinal neovascularization. Targeting Mèuller cells may be an effective strategy to prevent retinal neovascularization under pathological conditions. ... The hypoxia regulated, glial specific vector successfully reduced the abnormal neovascularization in the periphery by 93% and reduced the central vasobliterated area by 90%. A substantial amount of exogenous endostatin was produced in the retinas of P17 OIR mice. A significant increase in human endostatin protein and reduced vascular endothelial growth factor (VEGF) were identified by Western blot and ELISA, respectively. These findings suggest hypoxia-regulated, glial cell-specific scAAV mediated gene expression may be useful to prevent blindness found in devastating retinal diseases involving neovascularization.
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Date Issued: 2012
PURL: http://purl.flvc.org/FAU/3359290
Subject Headings: Diabetic retinopathy, Research, Methodology, Gene therapy, Retinal degeneration, Treatment, Neovascularization inhibitors, Mitochondrial pathology, Retina, Cytology, Gene mapping
Format: Document (PDF)

Title: Noninvasive Blood-Glucose Monitoring: A Microwave-based Biosensor Development.
Creator: Shankar, Poornima, Neelakanta, Perambur S., Florida Atlantic University, College of Engineering and Computer Science, Department of Computer and Electrical Engineering and Computer Science
Abstract/Description: This research refers to a proof-of-concept study concerning the development of a noninvasive blood-glucose monitoring system. The biosensor being considered is a microwave-based transducer (that can be rendered compatible for ISM band of 2450 MHz and hence Zigbee™ and/or BluetoothTM compliant). The goal of this study is tailored to develop eventually a unit for home-based healthcare and/or personalized wellness monitoring of diabetic patients. This pilot effort is expected to culminate in...
Show moreThis research refers to a proof-of-concept study concerning the development of a noninvasive blood-glucose monitoring system. The biosensor being considered is a microwave-based transducer (that can be rendered compatible for ISM band of 2450 MHz and hence Zigbee™ and/or BluetoothTM compliant). The goal of this study is tailored to develop eventually a unit for home-based healthcare and/or personalized wellness monitoring of diabetic patients. This pilot effort is expected to culminate in future in a wireless hyper/hypoglycemic risk-alert system and possible automatic insulin infusion pump activation efforts. The thesis addressed thereof provides details on the fundamentals of sensing glucose content noninvasively across a finger. The underlying principle of biosensing refers to detecting the change in the dielectric property of blood with differential changes in the glucose influx in the finger by sensing microwave (such as 2450 MHz) absorption and/or reflection so as to assay the glucose content of interest. Preliminary experimental and theoretical results are presented and discussed.
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Date Issued: 2008
PURL: http://purl.flvc.org/fau/fd/FA00012552
Subject Headings: Bioelectrochemistry--Research, Blood sugar monitoring, Diabetes--Risk factors--Identification, Biosensors--Materials, Microwave transmission lines, Microwave integrated circuits
Format: Document (PDF)

Title: A review of corporate-based wellness programs for general health promotion and prevention of type II diabetes mellitus.
Creator: Hemmings, Jodian R., Blanks, Robert H., Florida Atlantic University, Charles E. Schmidt College of Medicine, Department of Biomedical Science
Abstract/Description: This research focuses on obesity and other major risk factors for chronic diseases such as Type II Diabetes Mellitus, Heart Disease, and Stroke. Worksite wellness programs have been successful in this realm of health promotion and disease prevention for heart disease and stroke, but their effectiveness in treating diabetes has been uncertain partially due to poor patient compliance, lack of stress reduction strategies, poor diet and lack of persuasive health education on the risk of being...
Show moreThis research focuses on obesity and other major risk factors for chronic diseases such as Type II Diabetes Mellitus, Heart Disease, and Stroke. Worksite wellness programs have been successful in this realm of health promotion and disease prevention for heart disease and stroke, but their effectiveness in treating diabetes has been uncertain partially due to poor patient compliance, lack of stress reduction strategies, poor diet and lack of persuasive health education on the risk of being obese. Published peer-reviewed articles were reviewed, coded and analyzed to determine best practices, using a modified systematic review approach. The findings from these studies yield results that were used to develop a new employer-sponsored wellness program that is in accordance with the recently passed Affordable Care Act.
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Date Issued: 2014
PURL: http://purl.flvc.org/fau/fd/FA00004201, http://purl.flvc.org/fau/fd/FA00004201
Subject Headings: Behavior modification, Employee assistance programs, Health promotion, Medicine, Preventive, Non insulin dependent diabetes -- Prevention, obesity -- Risk factors, Preventive health services, Psychology, Industrial, Social responsibility of business, United States -- Patient Protection and Affordable Care Act
Format: Document (PDF)

FAU Theses and Dissertations (11)	+ -
FAU Undergraduate Student Research (1)	+ -

Diabetes (3)	+ -
Appetite disorders (1)	+ -
Behavior modification (1)	+ -
Bioelectrochemistry--Research (1)	+ -
Biosensors--Materials (1)	+ -

Blood sugar monitoring (1)	+ -
Caregivers (1)	+ -
Cognition disorders (1)	+ -
Complementary Therapies (1)	+ -
Computer modeling (1)	+ -
Computer simulation (1)	+ -
Culturally Competent Care--ethnology (1)	+ -
Cytology (1)	+ -
Diabetes Mellitus, Type 2 (1)	+ -
Diabetes--Alternative treatment (1)	+ -
Diabetes--Metabolism (1)	+ -
Diabetes--Prevention (1)	+ -
Diabetes--Risk factors (1)	+ -
Diabetes--Risk factors--Identification (1)	+ -
Diabetes--Social aspects (1)	+ -
Diabetes--Treatment (1)	+ -
Diabetic retinopathy (1)	+ -
Diabetics (1)	+ -
Employee assistance programs (1)	+ -
Ethnography (1)	+ -
Gene mapping (1)	+ -
Gene therapy (1)	+ -
Glucose--Metabolism (1)	+ -
Health education (1)	+ -
Health literacy (1)	+ -

Electronic Thesis or Dissertation (11)	+ -
poster (1)	+ -

Florida Atlantic University (10)	+ -
Christine E. Lynn College of Nursing (3)	+ -
College of Engineering and Computer Science (2)	+ -
Department of Computer and Electrical Engineering and Computer Science (2)	+ -
Neelakanta, Perambur S. (2)	+ -

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