Current Search: Breast -- Cancer -- Radiotherapy (x)
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- Title
- A method of verification of the total treatment time for the APBI (Accelerated Partial Breast Irradiation) devices: CONTURA Multilumen Balloon and SAVI Applicator.
- Creator
- Kyriacou, Andreas, Charles E. Schmidt College of Science, Department of Physics
- Abstract/Description
-
A simple method to verify the total treatment time generated by the treatment planning system (TPS) when the CONTURA MLB or the SAVI applicator are used for APBI treatments has been developed. The method compares the time generated by the TPS to a predicted time, calculated by inserting parameters obtained from the TPS in equations generated in this Thesis. The equations were generated by linearly fitting data from clinical cases that had been treated using the Contura MLB or the SAVI...
Show moreA simple method to verify the total treatment time generated by the treatment planning system (TPS) when the CONTURA MLB or the SAVI applicator are used for APBI treatments has been developed. The method compares the time generated by the TPS to a predicted time, calculated by inserting parameters obtained from the TPS in equations generated in this Thesis. The equations were generated by linearly fitting data from clinical cases that had been treated using the Contura MLB or the SAVI applicator at the Lynn Cancer Institute of the Boca Raton Regional Hospital. The parameters used were the PTV coverage, Air Kerma Strength, Balloon Volume (Contura data fit) and Evaluation PTV (SAVI data fit). As an outcome of this research, it is recommended that the plan should be reevaluated when the percent difference between the generated and the predicted times exceeds 5% for the Contura MLB, or 10% for the SAVI.
Show less - Date Issued
- 2011
- PURL
- http://purl.flvc.org/FAU/3332254
- Subject Headings
- Cancer, Radiotherapy, Breast, Cancer, Radiotherapy, Breast, Cancer, Treatment
- Format
- Document (PDF)
- Title
- Accurate verification of balloon rotation correction for the contura® multi-lumen device for accelerated partial breast irradiation.
- Creator
- Kyriacou, Andreas, Benda, R., Vargas, C., Lyden, M., Vicini , F., Leventouri, Theodora, Graduate College, Kasper, M.
- Date Issued
- 2011-04-08
- PURL
- http://purl.flvc.org/fcla/dt/3171046
- Subject Headings
- Breast --Cancer --Radiotherapy, Brachytherapy, Breast Neoplasms --surgery
- Format
- Document (PDF)
- Title
- Variations of Pericardial Dose at Different Respiratory Status in Accelerated Partial Breast Irradiation (APBI) Using Cyberknife M6™ Multileaf Collimators (CKMLC).
- Creator
- Long, Samanthia C., Shang, Charles, Leventouri, Theodora, Florida Atlantic University, Charles E. Schmidt College of Science, Department of Physics
- Abstract/Description
-
The purpose of this study is to investigate the changes of the pericardial dose at different respiratory phases and statuses in accelerated partial breast irradiation (APBI) using Cyberknife M6™ multileaf collimators (CK-MLC). Anonymous 6 female patient files with respiration gated four-dimensional computed tomography (4DCT) sets, and 6 left breast cancer cases with CT images in free-breathing (FB) and deep inhalation breath-hold (BH) were selected. One CT image set from each patient was...
Show moreThe purpose of this study is to investigate the changes of the pericardial dose at different respiratory phases and statuses in accelerated partial breast irradiation (APBI) using Cyberknife M6™ multileaf collimators (CK-MLC). Anonymous 6 female patient files with respiration gated four-dimensional computed tomography (4DCT) sets, and 6 left breast cancer cases with CT images in free-breathing (FB) and deep inhalation breath-hold (BH) were selected. One CT image set from each patient was planned for APBI in Accuray Multiplan™ 5.2, and respectively compared its pericardial dose with those from CT sets of other respiratory phases. All the comparable CT images were fused in the planning system according to the left chest wall, among which the lung gap anterior to the pericardium varies by the lung expansion. For the purpose of this study, the tumor volume was outlined in the media-lower quadrant of the left breast where this lung gap is relatively small. All the plans in this study met the requirements set by the National Surgical Adjuvant Breast and Bowel Project/Radiation Therapy Oncology Group (NSABP/RTOG), specifically protocol B-39/RTOG 0413. From the comparisons in this investigation, the mean relative pericardial dose of the BH CT group showed significant or 45% (p < 0.01) lower value than that of FB CT group. However, in FB 4DCT group, 3 of 6 cases indicated a meaningful reduction (p < 0.05) in 100% inhalation phase when compared with the mean dose over other phases. The inconsistent pericardial doses were displayed in FB 4DCT group due to minimal changes in the anterior lung gap of the pericardium, when the diaphragmatic breathing was dominant in those patients.
Show less - Date Issued
- 2015
- PURL
- http://purl.flvc.org/fau/fd/FA00004518, http://purl.flvc.org/fau/fd/FA00004518
- Subject Headings
- Breast--Cancer--Radiotherapy., Breast--Cancer--Treatment., Radiation--Measurement--Methodology., Medical physics.
- Format
- Document (PDF)
- Title
- Dose Validation for Partial Accelerated Breast Irradiation treated with the SAVI Applicator.
- Creator
- Pinder, Janeil K., Pella, Silvia, Leventouri, Theodora, Florida Atlantic University, Charles E. Schmidt College of Science, Department of Physics
- Abstract/Description
-
The purpose of this study is to verify and validate the dose at various points of interest in accelerated partial breast irradiation (APBI) treated with the Strut Adjusted Volume Implant (SAVI) applicator using Thermoluminescent Dosimeters (TLDs). A set of CT images were selected from a patient’s data who had received APBI using the SAVI applicator. The images were used to make 3D models. TLDs were calibrated for Brachytherapy. Various points of interest were marked out and slots were carved...
Show moreThe purpose of this study is to verify and validate the dose at various points of interest in accelerated partial breast irradiation (APBI) treated with the Strut Adjusted Volume Implant (SAVI) applicator using Thermoluminescent Dosimeters (TLDs). A set of CT images were selected from a patient’s data who had received APBI using the SAVI applicator. The images were used to make 3D models. TLDs were calibrated for Brachytherapy. Various points of interest were marked out and slots were carved in the 3D models to fit the TLDs. CT scans were taken of the 3D models with expanded SAVI applicator inserted. A plan was made following B-39 protocol. The TLDs were read and the absorbed doses were calculated and compared to the delivered doses. The results of this study show that the overall average reading of the TLDs is within expected value. The TPS shows overestimated dose calculations for brachytherapy.
Show less - Date Issued
- 2017
- PURL
- http://purl.flvc.org/fau/fd/FA00005942
- Subject Headings
- Dissertations, Academic -- Florida Atlantic University, Thermoluminescence dosimetry., Brachytherapy., Radiotherapy Dosage., Breast--Cancer--Radiotherapy.
- Format
- Document (PDF)
- Title
- Dosimetric and Radiobiological Comparison of Forward Tangent Intensity Modulated Radiation Therapy (FT-IMRT) and Volumetric Modulated Arc Therapy (VMAT) for Early Stage Whole Breast Cancer.
- Creator
- Moshiri Sedeh, Nader, Pella, Silvia, Leventouri, Theodora, Florida Atlantic University, Charles E. Schmidt College of Science, Department of Physics
- Abstract/Description
-
Intensity Modulated Radiation Therapy (IMRT) is a well-known type of external beam radiation therapy. The advancement in technology has had an inevitable influence in radiation oncology as well that has led to a newer and faster dose delivery technique called Volumetric Modulated Arc Therapy (VMAT). Since the presence of the VMAT modality in clinics in the late 2000, there have been many studies in order to compare the results of the VMAT modality with the current popular modality IMRT for...
Show moreIntensity Modulated Radiation Therapy (IMRT) is a well-known type of external beam radiation therapy. The advancement in technology has had an inevitable influence in radiation oncology as well that has led to a newer and faster dose delivery technique called Volumetric Modulated Arc Therapy (VMAT). Since the presence of the VMAT modality in clinics in the late 2000, there have been many studies in order to compare the results of the VMAT modality with the current popular modality IMRT for various tumor sites in the body such as brain, prostate, head and neck, cervix and anal carcinoma. This is the first study to compare VMAT with IMRT for breast cancer. The results show that the RapidArc technique in Eclipse version 11 does not improve all aspects of the treatment plans for the breast cases automatically and easily, but it needs to be manipulated by extra techniques to create acceptable plans thus further research is needed.
Show less - Date Issued
- 2015
- PURL
- http://purl.flvc.org/fau/fd/FA00004526, http://purl.flvc.org/fau/fd/FA00004526
- Subject Headings
- Breast -- Cancer -- Treatment, Cancer -- Radiation therapy, Image guided radiation therapy, Radiation dosimetry, Radiotherapy -- Technological innovations
- Format
- Document (PDF)