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Title: FAU Navigation System.
Creator: Cerezo, Maria, Barbosa, Edgard, Rezler, Evonne, Nguyen, Tony
Abstract/Description: The navigational system at Florida Atlantic University Boca Raton campus does not provide efficient travel for visitors, students, and faculty. Results from a survey shows 8 out of 10 people are being misdirected around the Boca Raton campus causing delays, traffic, and frustration. The architectural design of the Boca Raton campus buildings makes navigating even more difficult because of their identical qualities. The directory maps on campus fail to inform current position, are visually...
Show moreThe navigational system at Florida Atlantic University Boca Raton campus does not provide efficient travel for visitors, students, and faculty. Results from a survey shows 8 out of 10 people are being misdirected around the Boca Raton campus causing delays, traffic, and frustration. The architectural design of the Boca Raton campus buildings makes navigating even more difficult because of their identical qualities. The directory maps on campus fail to inform current position, are visually overwhelming and are outdated. From the research collected, we will create a cohesive navigational system that makes travel easier for visitors, students, and faculty. The new navigational system will comprise of a redesigned directory, numeric building signage, route markers, and an instruction manual.
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Date Issued: 2014
PURL: http://purl.flvc.org/fau/fd/FA0005008
Subject Headings: College students --Research --United States.
Format: Document (PDF)

Title: Exploring cation-π interactions in a sophomore Organic Chemistry Laboratory experiment.
Creator: Horowitz, Andrew, Rucco, Dominic, St. Germain, Elijah, Lepore, Salvatore D., Rezler, Evonne
Abstract/Description: An Organic Chemistry Lab experiment is being developed and adapted from work recently published by Maity and Lepore [1] investigating the cyclization of substituted β-alkynyl hydrazines to yield azaproline derivatives. The mechanism of this reaction is putatively driven by cation-π interaction of alkynyl hydrazine with a tetrabutylammonium ion. This experiment will present students with a cutting-edge research concept to explore the role of tetrabutylammonium in the cyclization of substituted...
Show moreAn Organic Chemistry Lab experiment is being developed and adapted from work recently published by Maity and Lepore [1] investigating the cyclization of substituted β-alkynyl hydrazines to yield azaproline derivatives. The mechanism of this reaction is putatively driven by cation-π interaction of alkynyl hydrazine with a tetrabutylammonium ion. This experiment will present students with a cutting-edge research concept to explore the role of tetrabutylammonium in the cyclization of substituted β-alkynyl hydrazines. Reaction kinetics will be probed by thin-layer chromatography and azaproline derivative product(s) will be characterized by IR spectroscopy. Ultimately, our goal is to implement a modern research-based, cost-effective, and safe bioorganic experiment into Florida Atlantic University’s undergraduate Organic Chemistry Laboratory curriculum.
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Date Issued: 2014
PURL: http://purl.flvc.org/fau/fd/FA0005024
Subject Headings: College students --Research --United States.
Format: Document (PDF)

Title: Stucco Removal Engineering.
Creator: Shaw, Brandon, Murphy, Jonathan, Trotsek, Dylan, Meeroff, Daniel E., Cowan, David, College of Engineering and Computer Science
Abstract/Description: Construction workers are exposed to fine particulate inhalation hazards during stucco removal. The ultimate goal of this research is to test a new chemical-assisted method that will reduce workers’ exposures to safer levels. To that end, the minimum specimen size must be determined that will replicate this hazardous work environment. Samples of concrete stucco surfacing material (CSSM) of various sizes ranging from 1-in×1-in. to 8-in.×16-in. were applied to masonry blocks. These specimens...
Show moreConstruction workers are exposed to fine particulate inhalation hazards during stucco removal. The ultimate goal of this research is to test a new chemical-assisted method that will reduce workers’ exposures to safer levels. To that end, the minimum specimen size must be determined that will replicate this hazardous work environment. Samples of concrete stucco surfacing material (CSSM) of various sizes ranging from 1-in×1-in. to 8-in.×16-in. were applied to masonry blocks. These specimens were tested to determine the minimum size needed to produce 150-mg/m3 (one order of magnitude larger than the OSHA exposure limit of 15-mg/m3) of airborne particulate in a 1-m3 test chamber when removed with a chipping hammer. Testing results revealed that 5-in.× 5-in. specimen size yielded on average 180-mg/m3 of particulates.
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Date Issued: 2015
PURL: http://purl.flvc.org/fau/fd/FA00005210
Subject Headings: College students --Research --United States.
Format: Document (PDF)

Title: Pentraxin 3 Reactivity to Acute Exercise in Obese Individuals.
Creator: Maharaj, Arun, Urtula, Alyssa M., Slusher, Aaron L., Mock, J. Thomas, Fisher, Craig B., Huang, Chun-Jung
Abstract/Description: Pentraxin 3 (PTX3) has been demonstrated as a vital biomarker for chronic inflammatory diseases. Decreased plasma PTX3 has been observed in obese populations. However, no studies have examined the impact of obesity on PTX3 reactivity to exercise. Therefore, our study sought to investigate PTX3 plasma response to maximal exercise in obese and normal-weight subjects, and its relationship with insulin sensitivity. Twenty-one subjects (9 obese and 12 normal-weight) were recruited. Plasma PTX3,...
Show morePentraxin 3 (PTX3) has been demonstrated as a vital biomarker for chronic inflammatory diseases. Decreased plasma PTX3 has been observed in obese populations. However, no studies have examined the impact of obesity on PTX3 reactivity to exercise. Therefore, our study sought to investigate PTX3 plasma response to maximal exercise in obese and normal-weight subjects, and its relationship with insulin sensitivity. Twenty-one subjects (9 obese and 12 normal-weight) were recruited. Plasma PTX3, insulin, and glucose levels were measured before and following exercise. While our results showed lower resting PTX3 levels in obese subjects, exercise elicited similar elevations in PTX3 and insulin sensitivity in both groups. Furthermore, PTX3 area-under-curve (AUC) was correlated with glucose AUC, even when controlled for body mass index and fitness level. These findings suggest that glucose may potentially regulate PTX3 response to exercise. Further investigation is needed to verify the impact of substrate utilization on exercise-induced PTX3 elevation.
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Date Issued: 2014
PURL: http://purl.flvc.org/fau/fd/FA0005028
Subject Headings: College students --Research --United States.
Format: Document (PDF)

Title: A Misuse Pattern for Flame.
Creator: Lewis, Paul, Singh, Sanjay, Fernandez, Eduardo B.
Abstract/Description: Flame is a computer worm that is being used for targeted cyber espionage in Middle Eastern countries. It is considered one of the most complex malware ever found. Flame can record audio, screenshots, keyboard activity and network traffic. It also has a kill switch to erase itself. Its program modules are encrypted. We are writing a misuse pattern to describe its architecture. A pattern is a solution to a recurrent problem in a given context. A pattern embodies the knowledge and experience of...
Show moreFlame is a computer worm that is being used for targeted cyber espionage in Middle Eastern countries. It is considered one of the most complex malware ever found. Flame can record audio, screenshots, keyboard activity and network traffic. It also has a kill switch to erase itself. Its program modules are encrypted. We are writing a misuse pattern to describe its architecture. A pattern is a solution to a recurrent problem in a given context. A pattern embodies the knowledge and experience of software developers and can be reused in new applications. A security pattern describes a mechanism or procedure to defend against an attack. A misuse pattern describes how a misuse is performed from the point of view of the attacker. It defines the environment where the attack is performed, countermeasures to stop it, and provides forensic information in order to trace the attack once it happens.
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Date Issued: 2014
PURL: http://purl.flvc.org/fau/fd/FA0005027
Subject Headings: College students --Research --United States.
Format: Document (PDF)

Title: Multi-factor Authentication.
Creator: Callahan, Colin, Fernandez, Eduardo B., College of Engineering and Computer Science
Abstract/Description: An important authentication method is multi-factor authentication (MFA). Products such as Enterprise Office 365 are already using it, available for any user in Office 365 Midsize Business, Enterprise, Academic, and Nonprofit plans as well as the standalone versions of Exchange Online and SharePoint Online. The log-in verification feature is aimed at reducing users' vulnerability to online identity theft, phishing, and other scams by adding a second level of authentication to an account log-in...
Show moreAn important authentication method is multi-factor authentication (MFA). Products such as Enterprise Office 365 are already using it, available for any user in Office 365 Midsize Business, Enterprise, Academic, and Nonprofit plans as well as the standalone versions of Exchange Online and SharePoint Online. The log-in verification feature is aimed at reducing users' vulnerability to online identity theft, phishing, and other scams by adding a second level of authentication to an account log-in. Twitter, Apple, PayPal, Google, Facebook, and other vendors already have implemented it. After correctly entering their username and password, users need to acknowledge a phone call, text message, or an app notification on their smartphone before they can gain access to their account. Two-factor authentication is the most common form of MFA and requires the use of two of the three authentication factors: Something only the user knows, something the user has, and something only the user is. In this work we will analyze some varieties, do UML models of their structure and dynamics, and compare MFA to other authentication approaches.
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Date Issued: 2015
PURL: http://purl.flvc.org/fau/fd/FA00005179
Subject Headings: College students --Research --United States.
Format: Document (PDF)

Title: Misuse Pattern: Keyboard Injection Through The USB Human Interface Device Class.
Creator: To, Dyllan, Fernandez, Eduardo B., College of Engineering and Computer Science
Abstract/Description: We are presenting a misuse pattern, Keyboard Injection through the USB Human Interface Device(HID) class. This paper describes how such a misuse is performed from the view from an attacker, describes the systems involved in the misuse, analyzes methods of stopping or preventing the attack through potential security patterns, and details techniques that can be used to detect or trace such an attack after it has occurred. Such a pattern can inform IT managers, device manufacturers, or even...
Show moreWe are presenting a misuse pattern, Keyboard Injection through the USB Human Interface Device(HID) class. This paper describes how such a misuse is performed from the view from an attacker, describes the systems involved in the misuse, analyzes methods of stopping or preventing the attack through potential security patterns, and details techniques that can be used to detect or trace such an attack after it has occurred. Such a pattern can inform IT managers, device manufacturers, or even device driver developers of the vulnerability, as well as detail methods or security patterns that can prevent an attack. A keyboard injection misuse attempts to infiltrate a system or network through a variety of techniques. Such a misuse impersonates a keyboard HID, which most systems inherently trust.
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Date Issued: 2015
PURL: http://purl.flvc.org/fau/fd/FA00005214
Subject Headings: College students --Research --United States.
Format: Document (PDF)

Title: Limited Movement Assistant for Arthritic Hands (LMAAH).
Creator: Pipitone, Anthony, Foley, Michael, Ferouz, Amir, McAlistar, Jonathan, Engeberg, Erik, College of Engineering and Computer Science
Abstract/Description: The purpose of this project is to create a mobile remote controller that operates a mechanical device that plays the piano. We have in our means to design a finger and wrist system that can play every key on the piano. The group has created 4 fingers that play the piano by pulling tendons on a robotic hand. The remote input device is a gloved sensor fitted with flexing sensors that monitor an arthritic patient’s joint movement. The controller then sends the signal to be amplified to a normal...
Show moreThe purpose of this project is to create a mobile remote controller that operates a mechanical device that plays the piano. We have in our means to design a finger and wrist system that can play every key on the piano. The group has created 4 fingers that play the piano by pulling tendons on a robotic hand. The remote input device is a gloved sensor fitted with flexing sensors that monitor an arthritic patient’s joint movement. The controller then sends the signal to be amplified to a normal full range of motion. That signal is sent to the robotic hand which plays the piano. Linear movement of the wrist is transferred with a sliding device. This project was a success and actually was able to assist people in remotely playing a scale on the piano.
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Date Issued: 2015
PURL: http://purl.flvc.org/fau/fd/FA00005206
Subject Headings: College students --Research --United States.
Format: Document (PDF)

Title: A simple method for measuring antibiotic resistance in a community of bacteria.
Creator: Pelski, Ana, Samaroo, Sheynelle, Varughese, Vipin, Behr, Evalena, Browne, Trisha, Esiobu, Nwadiuto
Abstract/Description: Antibiotic resistant bacteria infiltrate drinking water, increase human exposure, and spread into clinical settings. Regulatory agencies need simple test for ARI to monitor environmental quality. This study is first to measure resistance in a consortium of bacteria, not pure cultures. Our rapid method – “In-the-zone” (ITZ) employs a) the size of zones of inhibition b) identity of bacteria in the zone c) number of resistant clones within zones of inhibition and d) type of antibiotic to compute...
Show moreAntibiotic resistant bacteria infiltrate drinking water, increase human exposure, and spread into clinical settings. Regulatory agencies need simple test for ARI to monitor environmental quality. This study is first to measure resistance in a consortium of bacteria, not pure cultures. Our rapid method – “In-the-zone” (ITZ) employs a) the size of zones of inhibition b) identity of bacteria in the zone c) number of resistant clones within zones of inhibition and d) type of antibiotic to compute ARI. Results can be obtained within 24 - 48 hrs with very little effort. This semester, we repeated the test and validated the weighting of various parameters. The ITZ assay yield consistent and reproducible data on zones of inhibition of bacteria community. The diameter of inhibition zones was the most important parameter distinguishing resistomes of varying ARI. Landfill, manured garden, and waste plant samples scored highest in antibiotic resistance index compared to beach sand.
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Date Issued: 2014
PURL: http://purl.flvc.org/fau/fd/FA0005034
Subject Headings: College students --Research --United States.
Format: Document (PDF)

Title: TruD's Effect On RNA Oxidation.
Creator: Mills, Darius, Martin, Narelle, Rodriguez, Gabriela, Li, Zhongwei
Abstract/Description: Age-related neurodegenerative diseases impact society in an increasing rate. Oxidative damage to cellular molecules is considered the main cause of many neurological diseases such as, Alzheimer’s disease, Parkinson’s disease, etc. Understanding the mechanism and what cleans up oxidized molecules is vital in order to further explore therapeutic research for neurodegenerative diseases. RNA damage is potentially a major contributor to these diseases. However, compared to our knowledge about DNA,...
Show moreAge-related neurodegenerative diseases impact society in an increasing rate. Oxidative damage to cellular molecules is considered the main cause of many neurological diseases such as, Alzheimer’s disease, Parkinson’s disease, etc. Understanding the mechanism and what cleans up oxidized molecules is vital in order to further explore therapeutic research for neurodegenerative diseases. RNA damage is potentially a major contributor to these diseases. However, compared to our knowledge about DNA, little is known about the mechanism that cells use to eliminate damaged RNA. Our objective in this study is to understand the role of proteins that specifically bind oxidized RNA. We will focus on one such protein TruD in Escherichia coli. By studying how TruD and its mutants help E. coli to survive oxidative stress, we hope to elucidate a mechanism by which cells fight against RNA oxidation, and to suggest disease-preventing mechanisms by the human TruD homologs on a molecular level.
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Date Issued: 2014
PURL: http://purl.flvc.org/fau/fd/FA0005030
Subject Headings: College students --Research --United States.
Format: Document (PDF)

Title: FAU 2016 3MT® Three Minute Thesis Championship - Kyle Newton.
Creator: Newton, Kyle C., Graduate College
Abstract/Description: The 3MT® competition celebrates the exciting research conducted by graduate students. Developed by The University of Queensland (UQ), the exercise cultivates students’ academic, presentation, and research communication skills. The competition supports their capacity to effectively explain their research in three minutes, in language appropriate to a non-specialist audience. The first 3MT® competition was held at the University of Queensland in 2008 with 160 students competing. In 2009 and...
Show moreThe 3MT® competition celebrates the exciting research conducted by graduate students. Developed by The University of Queensland (UQ), the exercise cultivates students’ academic, presentation, and research communication skills. The competition supports their capacity to effectively explain their research in three minutes, in language appropriate to a non-specialist audience. The first 3MT® competition was held at the University of Queensland in 2008 with 160 students competing. In 2009 and 2010 the 3MT® competition was promoted to other Australian and New Zealand universities and enthusiasm for the concept grew. Since 2011, the popularity of the competition has increased and 3MT® competitions are now held in over 170 universities across more than 18 countries worldwide.
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Date Issued: 2016
PURL: http://purl.flvc.org/fau/fd/FA00005382
Subject Headings: College students --Research --United States.
Format: Video file

Title: Sexual and Ontogenetic Dimorphisms in the Anterior Lateral Line Nerve of the Yellow Singray, Urobatis jamaicensis.
Creator: Kramer, Katie, Newton, Kyle C., Kajiura, Stephen M., Office of Undergraduate Research and Inquiry
Abstract/Description: To fully understand the function of the elasmobranch electrosensory system it is necessary to examine electrosensory nerves extending from the ampullae of Lorenzini to the central nervous system. Studies detailing the composition of sensory axons are rare, but they have shown that ontogenetic and sexual dimorphism exists in the anterior lateral line nerve (ALLN) of numerous species. This study obtained a count of the number of axons comprising the ALLN in male vs. female and adult vs....
Show moreTo fully understand the function of the elasmobranch electrosensory system it is necessary to examine electrosensory nerves extending from the ampullae of Lorenzini to the central nervous system. Studies detailing the composition of sensory axons are rare, but they have shown that ontogenetic and sexual dimorphism exists in the anterior lateral line nerve (ALLN) of numerous species. This study obtained a count of the number of axons comprising the ALLN in male vs. female and adult vs. juvenile yellow stingrays (Urobatis jamaicensis). We hypothesized that males have more axons than females, and that the number of axons is ontogenetically constant. We expect males to have 30% more axons in their ALLN, and that the number of axons is ontogenetically constant for both sexes. This study will provide unique data about the electrosensory nerves of Yellow stingrays that can be used in future studies to make comparisons between other species.
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Date Issued: 2017
PURL: http://purl.flvc.org/fau/fd/FA00005624
Subject Headings: College students --Research --United States.
Format: Document (PDF)

Title: Use of Drosophila melanogaster larvae to evaluate cardioactive peptides.
Creator: Alishaev, Zahava, Godenschwege, Tanja A., Mari, Frank
Abstract/Description: Conopeptides are found in the venom of marine cone snails, aiding in the paralysis of their prey, and have been shown to have potential therapeutic uses in humans. Conopressins are conopeptides that target vasopressin/oxytocin receptors in vascular smooth muscle cells that are found within blood vessels. The crustacean cardioactive peptide (CCAP) is a homologous peptide found in crustaceans and has been shown to behave as a cardioaccelerator in a homologous system. This study describes the...
Show moreConopeptides are found in the venom of marine cone snails, aiding in the paralysis of their prey, and have been shown to have potential therapeutic uses in humans. Conopressins are conopeptides that target vasopressin/oxytocin receptors in vascular smooth muscle cells that are found within blood vessels. The crustacean cardioactive peptide (CCAP) is a homologous peptide found in crustaceans and has been shown to behave as a cardioaccelerator in a homologous system. This study describes the effects of CCAP in Drosophila larvae. We find that CCAP has an inotropic effect by causing a change in the contraction of blood vessels. We further investigate the effects of another possibly cardioactive conopeptide, γ-conopressin-vil, in Drosophila larvae. Elucidating the effects of conopetides in Drosophila larvae may translate to cardioactive therapeutic uses in mammalian systems.
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Date Issued: 2014
PURL: http://purl.flvc.org/fau/fd/FA0005000
Subject Headings: College students --Research --United States.
Format: Document (PDF)

Title: A comparison of the red fire ant and gopher tortoise burrow distribution within the FAU preserve.
Creator: Nenkova, Anzehla, Frazier, Evelyn
Abstract/Description: The gopher tortoise (Gopherus polyphemus) is considered a threatened species throughout much of its range. Their decline is mainly attributed to habitat fragmentation and destruction. These habitat disturbances commonly favor invasive species such as the red fire ant (Solenopsis invicta). The red fire ant has been detected on aprons of gopher tortoise burrows at the FAU preserve and we would like to evaluate whether the distribution of red fire ants overlaps with that of the tortoises burrows...
Show moreThe gopher tortoise (Gopherus polyphemus) is considered a threatened species throughout much of its range. Their decline is mainly attributed to habitat fragmentation and destruction. These habitat disturbances commonly favor invasive species such as the red fire ant (Solenopsis invicta). The red fire ant has been detected on aprons of gopher tortoise burrows at the FAU preserve and we would like to evaluate whether the distribution of red fire ants overlaps with that of the tortoises burrows. Ant distribution was accessed at the FAU preserve by running 10 random 100m transect lines and placing sardine baits at every 20m interval. Preliminary data suggests that red fire ants were abundant in 70% of the transects; however, we were unable to establish a direct correlation between the distribution of gopher tortoise burrows and that of red fire ants. The ants were tentatively identified to subfamilies and further identification will be performed.
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Date Issued: 2014
PURL: http://purl.flvc.org/fau/fd/FA0005031
Subject Headings: College students --Research --United States.
Format: Document (PDF)

Title: FAU 2016 3MT® Three Minute Thesis Championship - Carlie Perricone.
Creator: Perricone, Carlie S., Graduate College
Abstract/Description: The 3MT® competition celebrates the exciting research conducted by graduate students. Developed by The University of Queensland (UQ), the exercise cultivates students’ academic, presentation, and research communication skills. The competition supports their capacity to effectively explain their research in three minutes, in language appropriate to a non-specialist audience. The first 3MT® competition was held at the University of Queensland in 2008 with 160 students competing. In 2009 and...
Show moreThe 3MT® competition celebrates the exciting research conducted by graduate students. Developed by The University of Queensland (UQ), the exercise cultivates students’ academic, presentation, and research communication skills. The competition supports their capacity to effectively explain their research in three minutes, in language appropriate to a non-specialist audience. The first 3MT® competition was held at the University of Queensland in 2008 with 160 students competing. In 2009 and 2010 the 3MT® competition was promoted to other Australian and New Zealand universities and enthusiasm for the concept grew. Since 2011, the popularity of the competition has increased and 3MT® competitions are now held in over 170 universities across more than 18 countries worldwide.
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Date Issued: 2016
PURL: http://purl.flvc.org/fau/fd/FA00005378
Subject Headings: College students --Research --United States.
Format: Video file

Title: Epidemiology of alcohol use among Florida college students.
Creator: Keim, Carley, Gonzalez, Paz B., Avila, R.R., Rosselli, Monica
Abstract/Description: When considering the evolving nature of problematic drinking, it is important to continually assess its prevalence throughout various demographics. Our goal was to analyze significant demographical data from a longitudinal pilot study measuring drinking behavior relative to inhibitory functioning among the young adult college population. Post hoc analyses revealed that when comparing African Americans (M=19.40, SD=±3.286) to European Americans (M=15.75, SD=±2.173) and Hispanics/Latinos (M=16...
Show moreWhen considering the evolving nature of problematic drinking, it is important to continually assess its prevalence throughout various demographics. Our goal was to analyze significant demographical data from a longitudinal pilot study measuring drinking behavior relative to inhibitory functioning among the young adult college population. Post hoc analyses revealed that when comparing African Americans (M=19.40, SD=±3.286) to European Americans (M=15.75, SD=±2.173) and Hispanics/Latinos (M=16.06, SD=±2.886), African Americans reported a significantly older age of drinking onset. ANOVA analyses revealed men and European Americans to consume significantly more alcohol than others. The age at which one began drinking significantly predicted numerous drinking behaviors: average number of drinks consumed, b=-.35, t(47)=-2.56, p < .05; largest number of drinks consumed per occasion, b=-.43, t(48)=-3.26, p < .01. Conversely, older age of one’s first binge drinking experience significantly predicted future frequent drinking behaviors.
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Date Issued: 2014
PURL: http://purl.flvc.org/fau/fd/FA0005026
Subject Headings: College students --Research --United States.
Format: Document (PDF)

Title: Associations Between Alcohol and Drug Use Among Collegiate Young Adults: Preliminary Findings.
Creator: Gonzalez, Brianna, Paz, Andres L., Keim, C.A., Avila, R.R., Rosselli, Monica
Abstract/Description: The current study aims to examine correlates between binge drinking behavior with licit and illicit drug use among college students. Thirty-seven undergraduates (6 male) completed questionnaires concerning alcohol consumption throughout the one month duration of the study. Participants performed three cognitive computer tasks at both baseline (T1) and follow-up (T2) assessment. At T2 participants also filled out a drug usage questionnaire. This study stems from a larger longitudinal pilot...
Show moreThe current study aims to examine correlates between binge drinking behavior with licit and illicit drug use among college students. Thirty-seven undergraduates (6 male) completed questionnaires concerning alcohol consumption throughout the one month duration of the study. Participants performed three cognitive computer tasks at both baseline (T1) and follow-up (T2) assessment. At T2 participants also filled out a drug usage questionnaire. This study stems from a larger longitudinal pilot study. Strong correlations were found for increased cigarette use: the number of drinking days reported, r (34) = .442, p =.007, as well as non-binge drinking days and marijuana use, r (34) =.465, p =.004. Cigarette smokers were more likely than not to partake in multiple drinking behaviors. Marijuana was found to be used more on days in which binge drinking did not occur alluding to a preference to smoke rather than drink excessively while smoking marijuana.
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Date Issued: 2014
PURL: http://purl.flvc.org/fau/fd/FA0005019
Subject Headings: College students --Research --United States.
Format: Document (PDF)

Title: Enhanced CpG Activated Macrophage Killing of 3-Bromopyruvate Pre-treated 4T1 Breast Cancer Cells.
Creator: Rumicha, Dawit, Liddle, Genevieve M., Hartmann, James X., Office of Undergraduate Research and Inquiry
Abstract/Description: A common feature of breast cancer cells is the evasion of singular treatments by using the Warburg Effect, a process of metabolic ATP production through rapid anaerobic glycolysis. Cancer research has transitioned to an investigation of combination therapies to combat cancer. In our study, we seek to metabolically inhibit cancer cells before application of immunogenic killing. The Warburg Effect was targeted with 3-Bromopyruvate (3-BP), which blocks Glyceraldehyde 3-Phosphate Dehydrogenase ...
Show moreA common feature of breast cancer cells is the evasion of singular treatments by using the Warburg Effect, a process of metabolic ATP production through rapid anaerobic glycolysis. Cancer research has transitioned to an investigation of combination therapies to combat cancer. In our study, we seek to metabolically inhibit cancer cells before application of immunogenic killing. The Warburg Effect was targeted with 3-Bromopyruvate (3-BP), which blocks Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH) production. Treatment with 3-BP yielded up to 86.5% cancer cell death. Glycolytic inhibition renders cancer cells metabolically stressed, which may enable an effective immune response. Our hypothesis was that CpG activated macrophage will possess tumoricidal potential to target metabolically stressed cancer cells. Macrophages and CpG cultivation alone yielded a significant immune response. We sought to find a synergistic effect of 3-BP induced killing susceptibility with CpG activated macrophages may lead to an effective method of combination therapy.
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Date Issued: 2017
PURL: http://purl.flvc.org/fau/fd/FA00005634
Subject Headings: College students --Research --United States.
Format: Document (PDF)

Title: Identification of others through biological motion.
Creator: Fuller, Nicholas, Kersten, Alan, Earles, Julie
Abstract/Description: In point-light models, visual cues are reduced to points of light indicating the major points of movements of the human body. Although we are able to recognize people through movement, accuracy of identification of strangers through point-light models is low. Connecting the major points of motion to represent a skeleton might enhance the ability to recognize strangers. This study also wishes to assess whether accuracy will be improved through learning general movement characteristics of...
Show moreIn point-light models, visual cues are reduced to points of light indicating the major points of movements of the human body. Although we are able to recognize people through movement, accuracy of identification of strangers through point-light models is low. Connecting the major points of motion to represent a skeleton might enhance the ability to recognize strangers. This study also wishes to assess whether accuracy will be improved through learning general movement characteristics of individuals. After a learning stage, participants were randomly assigned to match names with either point-light or skeleton models of actor movements. Two of the four actions performed by actors in the testing stage were previously seen during the learning stage. We expect identification from skeleton displays will be higher than for point light displays. We also expect higher accuracy for actions previously seen during the learning stage. The findings and their implications will be discussed.
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Date Issued: 2014
PURL: http://purl.flvc.org/fau/fd/FA0005017
Subject Headings: College students --Research --United States.
Format: Document (PDF)

Title: Variation in the Major Histocompatibility Gene is Maintained By Selection Imposed By Infectious Disease.
Creator: Blair, Zizah J., Hughes, Colin, Charles E. Schmidt College of Science
Abstract/Description: Major Histocompatibility (MH) genes play critical roles in mounting adaptive immune responses to infectious diseases and parasites. There are two classes of MH genes: Class I and II; Class II can be further divided into Class II A and II B genes, this study focuses on Class IIB. Class II B genes are exceptionally variable in sequence. Leading hypotheses propose that this genetic variation is maintained by selection for resistance to pathogens. Since pathogens are constantly evolving to avoid...
Show moreMajor Histocompatibility (MH) genes play critical roles in mounting adaptive immune responses to infectious diseases and parasites. There are two classes of MH genes: Class I and II; Class II can be further divided into Class II A and II B genes, this study focuses on Class IIB. Class II B genes are exceptionally variable in sequence. Leading hypotheses propose that this genetic variation is maintained by selection for resistance to pathogens. Since pathogens are constantly evolving to avoid detection, and new pathogens regularly enter populations, which MH proteins confer immunity fluctuates over time. This study examines MH Class II B in Centropomus undecimalis, the common Snook. Genes will be sequenced, and their variability quantified using approaches that include: database searches (NCBI), PCR, and sequencing. Sequencing of the MH gene will provide insight on how high polymorphism results from immune responses to infectious pathogens.
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Date Issued: 2015
PURL: http://purl.flvc.org/fau/fd/FA00005177
Subject Headings: College students --Research --United States.
Format: Document (PDF)

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