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Marine organisms as a source of novel lead structures for drug development
Isolation of marine natural products
The Lithistida: important sources of compounds useful in biomedical research
Chemistry and biology of the discodermolides, potent mitotic spindle poisons
Total synthesis of a potent hybrid of the anticancer natural products dictyostatin and discodermolide.
1,1-Dimethyl-5,6-dihydroxyindolinium chloride from a deep water marine sponge, Dercitus sp.
Interspecific differences in fouling of two congeneric ascidians (Eudistoma olivaceum and E. capsulatum): is surface acidity an effective defense?
Inhibition of larval settlement by natural products from the ascidian, Eudistoma olivaceum (Van Name)
Stereochemical determination of dictyostatin, a novel microtubule-stabilising macrolide from the marine sponge Corallistidae sp.
Cytotoxin production by a marine Lyngbya strain (cyanobacterium) in a large-scale laboratory bioreactor
A mammalian cell agar-diffusion assay for the detection of toxic compounds
Development of techniques for in vitro production of bioactive natural products from marine sponges
Tubulin polymerizing activity of dictyostatin-1, a polyketide of marine sponge origin
Two New Cytotoxic Linderazulenes from a Deep-Sea Gorgonian of the Genus Paramuricea
Eryloside E from an Atlantic sponge Erylus goffrilleri
Total synthesis of a library of designed hybrids of the microtubule-stabilising anticancer agents taxol, discodermolide and dictyostatin
Total synthesis and biological evaluation of aseries of macrocyclic hybrids and analogues of the antimitotic natural products Dictyostatin,Discodermolide, and Taxol
Synthesis and biological evaluation of 10, 11-Dihydrodictyostatin, a potent analogue of the marine anticancer agent dictyostatin
Early effects of Lasonolide A on pancreatic cancer cells
Isospongiadiol, a cytotoxic and antiviral diterpene from a Caribbean deep water marine sponge, Spongia sp.

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