Current Search: Li, Yuejin (x)
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Title
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Correcting diastolic dysfunction by Ca2+ desensitizing Troponin in restrictive cardiomyopathy mice.
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Creator
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Li, Yuejin, Graduate College
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Date Issued
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2010-04-09
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PURL
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http://purl.flvc.org/fcla/dt/3176815
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Format
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Document (PDF)
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Title
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Dose-dependent arrhythmia and cardiac dysfunction in restrictive cardiomyopathy mice due to troponin mutations.
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Creator
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Li, Yuejin, Jean-Charles, Pierre-Yves, Nan, Changlong, Chen, Guozhen, Graduate College, Huang, Xupei
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Date Issued
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2011-04-08
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PURL
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http://purl.flvc.org/fcla/dt/3164611
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Subject Headings
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Arrhythmia --drug therapy, Heart failure, Proteomics
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Format
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Document (PDF)
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Title
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Pathogenesis of idiopathic restrictive cardiomyopathy.
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Creator
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Li, Yuejin, Charles E. Schmidt College of Medicine, Department of Biomedical Science
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Abstract/Description
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Restrictive cardiomyopathy (RCM) is a heart muscle disease, characterized by diastolic dysfunction. The present dissertation is to understand the mechanisms underlyijng the initiation of diastolic dysfunction and the fast disease progression to early death in a RCM mouse model, the transgenic cTnI193His mouse... These data showed that myocardial ischemia occurred after diastolic dysfunction and before systolic dysfunction which proceeded congestive heart failure. The results demonstrate that...
Show moreRestrictive cardiomyopathy (RCM) is a heart muscle disease, characterized by diastolic dysfunction. The present dissertation is to understand the mechanisms underlyijng the initiation of diastolic dysfunction and the fast disease progression to early death in a RCM mouse model, the transgenic cTnI193His mouse... These data showed that myocardial ischemia occurred after diastolic dysfunction and before systolic dysfunction which proceeded congestive heart failure. The results demonstrate that myocardial ischemia causing cardiomycete death is a link between the initial diastolic dysfunction and late-stage systolic dysfunction, and accelerates the disease progression to fatal heart failure in the early age.
Show less
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Date Issued
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2011
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PURL
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http://purl.flvc.org/fcla/dt/3362045
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Subject Headings
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Mice as laboratory animals, Heart conduction system, Cardiovascular system, Diseases, Genetic aspects
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Format
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Document (PDF)
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Title
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N-terminal truncated cardiac TnI improves cardiac function in vivo and rescues restrictive cardiomyopathy.
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Creator
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Jean-Charles, Pierre-Yves, Li, Yuejin, Nan, Changlong, Chen, Guozhen, Feng, H., Huang, Xupei, Jin, J.P., Graduate College
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Date Issued
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2011-04-08
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PURL
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http://purl.flvc.org/fcla/dt/3164515
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Subject Headings
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Cardiac arrest, Troponin --diagnostic use, Transgenic mice
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Format
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Document (PDF)
