Current Search: Wright, Amy E. (x)
Pages
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Title
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Leiodermatolide, a potent antimitotic macrolide from the marine sponge Leiodermatium sp.
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Creator
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Paterson, Ian, Dalby, S. M., Roberts, J. C., Naylor, G. J., Guzman, Esther A., Isbrucker, Richard A., Pitts, Tara P., Linley, P. A., Divlianska, D. B., Reed, John K., Wright, Amy E.
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Date Issued
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2011
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PURL
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http://purl.flvc.org/fau/fd/FA00007465
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Subject Headings
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Antimitotic Agents, Macrolides, Sponges, Molecular structure, Nuclear Magnetic Resonance, Biomolecular, Cell lines
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Format
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Document (PDF)
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Title
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Characterization and optimization of in vitro assay conditions for (1,3)β-glucan synthase activity from Aspergillus fumigatus and Candida albicans for enzyme inhibition screening.
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Creator
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Wood, R. L., Miller, T. K., Wright, Amy E., McCarthy, Peter J., Taft, C. S., Pomponi, Shirley A., Selitrennikoff, Claude, Harbor Branch Oceanographic Institute
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Date Issued
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1998
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PURL
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http://purl.flvc.org/FCLA/DT/3351974
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Subject Headings
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Aspergillus fumigatus, Candida albicans, Glucosyltransferases, In vitro, Glucan synthase, Enzyme inhibitors
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Format
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Document (PDF)
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Title
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Eryloside F, a Novel Penasterol Disaccharide Possessing Potent Thrombin Receptor Antagonist Activity.
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Creator
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Stead, Paul, Hiscox, Steve, Robinson, Phil S., Pike, Nicholas B., Sidebottom, Philip J., Roberts, Andrew D., Taylor, Nicholas L., Wright, Amy E., Pomponi, Shirley A., Langley, David
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Date Issued
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2000
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PURL
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http://purl.flvc.org/FCLA/DT/2848300
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Subject Headings
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Disaccharides --Conformations, Peptide drugs, Hepatocyte growth factor --Receptors, Sponges, Steroid harmone metabolism
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Format
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Document (PDF)
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Title
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Novel steroidal saponins, Sch 725737 and Sch 725739, from a marine starfish, Novodinia antillensis.
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Creator
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Yang, Shu-Wei, Chan, Tze-Ming, Buevich, Alexei, Priestley, T., Crona, J., Reed, John K., Wright, Amy E., Patel, Mahesh, Gullo, Vincent, Chen, Guodong, Pramanik, B., Chu, Min
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Date Issued
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2007
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PURL
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http://purl.flvc.org/FCLA/DT/3343845
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Subject Headings
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Steroid saponins, Starfishes
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Format
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Document (PDF)
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Title
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A New Sterol Sulfate, Sch 572423, from a Marine Sponge, Topsentia sp.
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Creator
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Yang, Shu-Wei, Buevich, Alexei, Chan, Tze-Ming, Smith, Michelle, Lachowicz, Jean, Pomponi, Shirley A., Wright, Amy E., Mierzwa, Ronald, Patel, Mahesh, Gullo, Vincent, Chu, Min
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Date Issued
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2003
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PURL
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http://purl.flvc.org/FCLA/DT/2827816
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Subject Headings
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Water quality bioassay, Water --Pollution --Toxicology, Sponges, Marine ecosystem management, Filters and filtration
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Format
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Document (PDF)
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Title
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An Assessment of Potential Threats to Human Health from Algae Blooms in the Indian River Lagoon (USA) 2018–2021: Unique Patterns of Cytotoxicity Associated with Toxins.
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Creator
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Esther Guzman, Tara A. Peterson, Priscilla L. Winder, Kirstie T. Francis, Malcolm McFarland, Jill C. Roberts, Jennifer Sandle, Amy E. Wright
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Abstract/Description
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The Indian River Lagoon (IRL), a 156-mile-long estuary located on the eastern coast of Florida, experiences phytoplankton bloom events due to increased seasonal temperatures coupled with anthropogenic impacts. This study aimed to gather data on the toxicity to human cells and to identify secondary metabolites found in water samples collected in the IRL. Water samples from 20 sites of the IRL were collected during the wet and dry seasons over a three-year period. A panel of cell lines was used...
Show moreThe Indian River Lagoon (IRL), a 156-mile-long estuary located on the eastern coast of Florida, experiences phytoplankton bloom events due to increased seasonal temperatures coupled with anthropogenic impacts. This study aimed to gather data on the toxicity to human cells and to identify secondary metabolites found in water samples collected in the IRL. Water samples from 20 sites of the IRL were collected during the wet and dry seasons over a three-year period. A panel of cell lines was used to test cytotoxicity. Hemagglutination, hemolysis, and inhibition of protein phosphatase 2A (PP2A) were also measured. Cytotoxic blooms were seen both in the south (Microcystis) and the north (Pyrodinium) of the IRL. Each toxin induced a consistent pattern of cytotoxicity in the panel of human cell lines assayed. During blooms, cytotoxicity due to a single type of toxin is obvious from this pattern. In the absence of blooms, the cytotoxicity seen reflected either a mixture of toxins or it was caused by an unidentified toxin. These observations suggest that other toxins with the potential to be harmful to human health may be present in the IRL. Moreover, the presence of toxins in the IRL is not always associated with blooms of known toxin-producing organisms.
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Date Issued
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2023
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PURL
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http://purl.flvc.org/fau/fd/FAUIR000517
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Format
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Document (PDF)
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Title
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Preliminary cruise report: Submersible and scuba collections in the coastal waters of Honduras, the Bay Islands: Biomedical and biodiversity research of the benthic communities with emphasis on the porifera, algae and gorgonacea.
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Creator
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Reed, John K., Pomponi, Shirley A., Hanisak, M. Dennis, Wright, Amy E., Janda, Kathleen E., Pitts, Tara P., Willoughby, Robin, Killday, K. B., Robertson, Lynn, Lopez, Jose V., Kelly-Borges, Klaus, Overdorf, Laura S., Monaghan, Pat
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Date Issued
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1997-12-15
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PURL
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http://purl.flvc.org/fcla/dt/3359259
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Subject Headings
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Honduras, Biomedical Research, Biodiversity--Research
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Format
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Document (PDF)
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Title
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Isolation, synthesis, and biological activity of Aphrocallistin, an adenine-substituted bromotyramine metabolite from the hexactinellida sponge Aphrocallistes beatrix.
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Creator
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Wright, Amy E., Roth, G. P., Hoffman, J. K., Divlianska, D. B., Pechter, D., Sennett, Susan H., Guzman, Esther A., Linley, P. A., McCarthy, Peter J., Pitts, Tara P., Pomponi, Shirley A., Reed, John K.
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Date Issued
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2009
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PURL
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http://purl.flvc.org/FCLA/DT/3319109
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Subject Headings
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Sponges --Research, Marine metabolites, Marine natural products, Hexactinellida
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Format
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Document (PDF)
Pages
