Current Search: Pella, Silvia (x)
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Title
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Dosimetric Influence of Dose due to the PTV Dose Uniformity on the Critical Organs.
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Creator
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Yigit, Erdem, Pella, Silvia, Theodora Leventouri, Theodora Leventouri,, Florida Atlantic University, Department of Physics, Charles E. Schmidt College of Science
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Abstract/Description
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Dose uniformity in the Planning Target Volume (PTV) can induce a higher-than-expected dose distribution in the nearby critical organs. The goal of this study is to evaluate the influence of the Planning Target volume dose uniformity on the surrounding critical organs (OAR). Ten cases of anonymized patients’ data were selected for our study including: Breast cancer, Brain cancer, Head and Neck cancer, Lung and Prostate calculations of Conformity indices, Biological Effective Doses (BED), Tumor...
Show moreDose uniformity in the Planning Target Volume (PTV) can induce a higher-than-expected dose distribution in the nearby critical organs. The goal of this study is to evaluate the influence of the Planning Target volume dose uniformity on the surrounding critical organs (OAR). Ten cases of anonymized patients’ data were selected for our study including: Breast cancer, Brain cancer, Head and Neck cancer, Lung and Prostate calculations of Conformity indices, Biological Effective Doses (BED), Tumor Control Probability (TCP) and Normal Tissue Complication Probability (NTCP) were used to calculate the dose distribution in PTV as well as the dose delivered to the surrounding critical organs of each PTV. We assume that the tumors PTVs have homogeneous density as well as the surrounding normal tissue. Conformity indices (CI) for Breast (PTV) are between 1.8 – 1.9, for Brain (PTV) are between 1.6 – 2.0, for Lungs are 1.5 – 1.6, for Prostate are between 0.4 – 0.5, for Head and Neck are 0.3 – 0.4. Dose uniformity in all the PTVs is 1.089 which is a good indication of the quality of treatment delivered to the tumor. TCP is averaging of value of 87.94 and NTCP is 3.4445.
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Date Issued
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2023
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PURL
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http://purl.flvc.org/fau/fd/FA00014339
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Subject Headings
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Radiation dosimetry, Biophysics, Cancer
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Format
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Document (PDF)
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