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Title: Population Explosion of the hairy crazy ant, Paratrechina Pubens (Hymenoptera: Formicidae), on St. Croix, US Virgin Islands.
Creator: Wetterer, James K., Keularts, Jozef L. W.
Date Issued: 2008-09
PURL: http://purl.flvc.org/fau/fd/FAUIR000205
Format: Citation

Title: Spread in Trinidad of the South American Fire Ant Solenopsis invicta (Hymenoptera, Formicidae).
Creator: Wetterer, James K., Davis, Lloyd R., White, Graham L.
Date Issued: 2014-03
PURL: http://purl.flvc.org/fau/fd/FAUIR000213
Format: Citation

Title: 2D:4D FINGER RATIO IN CROSSFIT ATHLETES.
Creator: Wang, Calren, Wetterer, James, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: The second digit and fourth digit (2D:4D) finger ratio is known to be an indicator of in utero androgen influence. Here, I review current research concerning 2D:4D ratio, particularly in regards to muscle strength, muscle mass, and athletic ability. Studies on athletes have shown a significant negative correlation between the ratio and athleticism and an inconsistent correlation with muscle mass and muscle strength. I propose a research study on the relationship between the 2D:4D ratio and...
Show moreThe second digit and fourth digit (2D:4D) finger ratio is known to be an indicator of in utero androgen influence. Here, I review current research concerning 2D:4D ratio, particularly in regards to muscle strength, muscle mass, and athletic ability. Studies on athletes have shown a significant negative correlation between the ratio and athleticism and an inconsistent correlation with muscle mass and muscle strength. I propose a research study on the relationship between the 2D:4D ratio and Crossfit athletes and its relationship to muscle mass and muscle strength.
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Date Issued: 2018
PURL: http://purl.flvc.org/fau/fd/FAUHT00060
Format: Document (PDF)

Title: CAN BRAIN NATRIURETIC PEPTIDE BE A PROGNOSTIC INDICATOR FOR CONGESTIVE HEART FAILURE PATIENTS NEARING DEATH?.
Creator: Pisarra, Cory, Wetterer, James, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: The cardiac ventricles release brain natriuretic peptide (BNP) when the cardiomyocytes are exceptionally stressed. Past research has indicated that BNP can be a used as a prognostic indicator in heart failure patients (Doust et al., 2005). The hypothesis is that higher BNP readings will result in a shorter amount of time that the patient has to live. 210 patients with a heart condition were admitted to the Hospice of Palm Beach County and had their blood drawn to determine their BNP level;...
Show moreThe cardiac ventricles release brain natriuretic peptide (BNP) when the cardiomyocytes are exceptionally stressed. Past research has indicated that BNP can be a used as a prognostic indicator in heart failure patients (Doust et al., 2005). The hypothesis is that higher BNP readings will result in a shorter amount of time that the patient has to live. 210 patients with a heart condition were admitted to the Hospice of Palm Beach County and had their blood drawn to determine their BNP level; however, only 35 patients qualified for the final analysis. The 35 patients had BNP readings ranging from 63 pg/ml to 50000 pg/ml with the average being 6620 pg/ml, whereas the normal range is <100 pg/ml. The time between the last BNP reading and the date of death ranged from 1 day to 732 days with the average being 118 days; furthermore, the trend indicated that the higher the BNP level the shorter the patient had to live which agrees with the hypothesis.
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Date Issued: 2018
PURL: http://purl.flvc.org/fau/fd/FAUHT00042
Format: Document (PDF)

Title: DECISION-MAKING GAMES: EFFECTS ON FUTURE DECISIONS OF ADOLESCENTS.
Creator: Rivera, Dalian K., Wetterer, James K., Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: I propose research that examines whether decision making video games have positive effects on the everyday decision of adolescents. The research will be conducted on 30 adolescents/young adults, ages 18-24, who have very little gaming experience. Subjects will complete a survey examining their decision-making capabilities, problem-solving ability, and their mental speed. They will be randomly placed into two groups of 15, the experimental and the control. The experimental group will...
Show moreI propose research that examines whether decision making video games have positive effects on the everyday decision of adolescents. The research will be conducted on 30 adolescents/young adults, ages 18-24, who have very little gaming experience. Subjects will complete a survey examining their decision-making capabilities, problem-solving ability, and their mental speed. They will be randomly placed into two groups of 15, the experimental and the control. The experimental group will participate in an online decision-making game, Imprisoned and Alter Ego, for a total of five hours over a three-week period. The control group will not play any online games. I will then retest all the subjects. I hypothesize that moderate play of decision-making games by adolescents and young adults can improve the decision-making abilities in their everyday lives as well as enhance their problem-solving skills, and increase the speed of their thought processing capabilities.
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Date Issued: 2018
PURL: http://purl.flvc.org/fau/fd/FAUHT00045
Format: Document (PDF)

Title: DENTAL FEAR IN ADULTS.
Creator: Patel, Meera, Wetterer, James, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: Many people suffer a certain degree of dental fear, commonly brought on by an earlier negative experience or by anticipated pain. Dental fear may prevent people from receiving necessary treatment, ultimately worsening their health. To investigate how dental fear is related to age, the origin of dental fear, and preference of treatment options, a self-administered research survey was conducted. The results indicate younger participants claim a lower degree of dental fear in comparison to older...
Show moreMany people suffer a certain degree of dental fear, commonly brought on by an earlier negative experience or by anticipated pain. Dental fear may prevent people from receiving necessary treatment, ultimately worsening their health. To investigate how dental fear is related to age, the origin of dental fear, and preference of treatment options, a self-administered research survey was conducted. The results indicate younger participants claim a lower degree of dental fear in comparison to older participants. Results also showed both negative experience and anticipated pain as origins of dental fear for individuals. Participants also responded positively to music therapy in the waiting rooms/operatory rooms. Lastly, regardless of age and degree of dental fear, respondents preferred receiving both pharmaceutical and psychological treatment options. Future studies could investigate more on preventative care in dental offices and create treatment options based on sole individuals, age groups, origins of dental fear, and effectiveness.
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Date Issued: 2018
PURL: http://purl.flvc.org/fau/fd/FAUHT00038
Format: Document (PDF)

Title: USING eDNA ANALYSIS FROM WATER SAMPLES IN A COMMON SNOOK, CENTROPOMUS UNDECIMALIS, SURVEY.
Creator: Anderson, Ryan, Wetterer, James, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: Environmental DNA (eDNA) is genetic material an organism leaves behind in its habitat, originating from blood, waste, or shed skin, among other sources. In aquatic environments, it is possible to extract eDNA from water samples, allowing for a variety of genetic tests to be performed, with great value in the fields of endangered species protection, invasive species control, and fisheries management among others. eDNA can persist in freshwater environments for many hours and can be attributed...
Show moreEnvironmental DNA (eDNA) is genetic material an organism leaves behind in its habitat, originating from blood, waste, or shed skin, among other sources. In aquatic environments, it is possible to extract eDNA from water samples, allowing for a variety of genetic tests to be performed, with great value in the fields of endangered species protection, invasive species control, and fisheries management among others. eDNA can persist in freshwater environments for many hours and can be attributed to fish up to one kilometer upstream from the collection site. However, water conditions in marine environments may reduce the survivability of eDNA. I evaluated the reliability eDNA analysis in the marine environment by analyzing water samples taken immediately before a survey of the common snook, Centropomus undecimalis, an important game fish. The eDNA sampling method was successful at detecting snook presence in the Indian River Lagoon, although with some practical limitations.
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Date Issued: 2018
PURL: http://purl.flvc.org/fau/fd/FAUHT00002
Format: Document (PDF)

Title: The scientific and religious construction of female sexuality.
Creator: Lazo, Stephanie, Wetterer, James, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: The field of biology predominantly studies the structure and function of living entities, such as the human body, while women’s studies perspectives help to show the influence of culture and power on biological knowledge and principles. This thesis analyzes the scientific construction of female sexuality through the lenses of feminist science studies. The approach provides an understanding of how such ideas are imposed on Western women in particular, and the role that such women are expected...
Show moreThe field of biology predominantly studies the structure and function of living entities, such as the human body, while women’s studies perspectives help to show the influence of culture and power on biological knowledge and principles. This thesis analyzes the scientific construction of female sexuality through the lenses of feminist science studies. The approach provides an understanding of how such ideas are imposed on Western women in particular, and the role that such women are expected to play in demonstrating that they are virginal, chaste, and faithful/trustworthy to men. I explore both scientific and religious documents that discuss female sexuality through history. I argue that understanding the roles that science and religion play can tell us much about our current social relationships regarding gender and sexuality.
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Date Issued: 2018
PURL: http://purl.flvc.org/fau/fd/FAUHT00027
Format: Document (PDF)

Title: SPREAD OF AN EXOTIC TRAPJAW ANT ANOCHETUS MAYRI IN SOUTH FLORIDA.
Creator: Bryant, Andrew M., Wetterer, James, Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: Anochetus mayri is a widespread New World species, ranging from South and Central America and the West Indies, north to Florida and the Bahamas. Published records of A. mayri outside of the tropics come from six sites in Florida and two in the Bahamas . The northernmost published record of A. mayri came from the Pine Jog Environmental Learning Center in West Palm Beach, Florida, collected in 2002 in pine and oak litter samples. I examined whether A. mayri was also present in surrounding areas...
Show moreAnochetus mayri is a widespread New World species, ranging from South and Central America and the West Indies, north to Florida and the Bahamas. Published records of A. mayri outside of the tropics come from six sites in Florida and two in the Bahamas . The northernmost published record of A. mayri came from the Pine Jog Environmental Learning Center in West Palm Beach, Florida, collected in 2002 in pine and oak litter samples. I examined whether A. mayri was also present in surrounding areas with similar environmental conditions. I found A. mayri in pine litter at other sites in Palm Beach County, but I did not find this species in similar habitats in Lee County. Additional unpublished records indicate that A. mayri is widespread in deep pine litter in Florida north to Indian River County and West to Highlands County.
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Date Issued: 2018
PURL: http://purl.flvc.org/fau/fd/FAUHT00008
Format: Document (PDF)

Title: EXAMINATION OF NATURAL AND CAPTIVE BEHAVIORS AND THEIRIMPLICATIONS ON MENTAL HEALTH IN OCTOPUS VULGARIS.
Creator: Odom, Justin, Moore, Jon, Wetterer, James K., Harriet L. Wilkes Honors College
Abstract/Description: In an attempt to better understand the effects of environmental enrichments on captive octopods, specifically Octopus vulgaris, as conducted by aquariums, attempts have been made to collect wild octopus from various sites in the Indian River Lagoon. Collected specimen would have been observed in captivity in order to compare their behavior with that of their wild counterparts based on the data collected by Kayes in 1973. The research conducted would serve to investigate if the environmental...
Show moreIn an attempt to better understand the effects of environmental enrichments on captive octopods, specifically Octopus vulgaris, as conducted by aquariums, attempts have been made to collect wild octopus from various sites in the Indian River Lagoon. Collected specimen would have been observed in captivity in order to compare their behavior with that of their wild counterparts based on the data collected by Kayes in 1973. The research conducted would serve to investigate if the environmental enrichments, institutionalized by aquariums, encourage octopods to behave more closely to the natural or wild type behaviors or if the enrichments encourage less natural behavior. Due to complications in the collection process, the nature of research conducted was changed to look at behavior of 0. vulgaris in the wild at Blue Heron Bridge, while examining literature on implications of octopi behavior in captivity. Enrichment is used to guarantee the mental wellbeing and health of animals in captivity in the interests of maintaining a good quality of living. This thesis looks at whether the quality for life achieved by enrichment impacts behavior by either encouraging natural or unnatural behavior in octopi.
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Date Issued: 2014
PURL: http://purl.flvc.org/fau/fd/FA00003620
Format: Document (PDF)

Title: Bio-active organic compounds in the venom of an Endemic Jamaican Ant, Crematogaster vicina.
Creator: Burnett, Brian M, Wetterer, James K., Dragojlovic, Veljko, Harriet L. Wilkes Honors College
Abstract/Description: Bioprospecting, the search for useful compounds found in nature, has led to the discovery of novel drugs and pharmaceuticals. For my thesis research, I analyzed the organic compounds in the venom of Crematogaster vicina Andre, an endemic Jamaican ant. Prior chemical analysis of Crematogaster species revealed diverse, bio-active organic compounds, which included long chained conjugated dienones, furanocembranoid, and diterpenes. I postulated that these types of compounds are characteristic of...
Show moreBioprospecting, the search for useful compounds found in nature, has led to the discovery of novel drugs and pharmaceuticals. For my thesis research, I analyzed the organic compounds in the venom of Crematogaster vicina Andre, an endemic Jamaican ant. Prior chemical analysis of Crematogaster species revealed diverse, bio-active organic compounds, which included long chained conjugated dienones, furanocembranoid, and diterpenes. I postulated that these types of compounds are characteristic of the Crematogaster venom. I used Gas Chromatography- Mass Spectrometry (GC-MS), Sci-Finder database and SDBS database to test my hypothesis with C.vicina venom. I identified one bio-active organic compound of high abundance and similar characteristics of the organic compounds found in venom of the Crematogaster species from Europe: 1, 2 –Dihydro-4-ethylamino-1-methylpyrimidin-2-one, which I isolated as di (phosphate methyl ester).
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Date Issued: 2013
PURL: http://purl.flvc.org/fau/fd/FA00003508
Format: Document (PDF)

Title: Impact of reduction mowing on fire ants (Hymenoptera: Formiciade) at Gopher tortoise (Testudines: Testudinidae) burrows.
Creator: Jones, Richard, Wetterer, James K., Moore, Jon, Harriet L. Wilkes Honors College
Abstract/Description: Many species prey upon the threatened gopher tortoises, including the Red Imported Fir Ants Solenopsis invicta. While human alterations to native habitat have led to a decline in gopher tortoises, “disturbance specialists” like S. invicta often thrive on such changes. This study examines three ant surveys at gopher tortoise burrows within a section of residential “greenway” in southeastern Florida before and after “reduction mowing”. While the presence of S. invicta did decrease aftrer the...
Show moreMany species prey upon the threatened gopher tortoises, including the Red Imported Fir Ants Solenopsis invicta. While human alterations to native habitat have led to a decline in gopher tortoises, “disturbance specialists” like S. invicta often thrive on such changes. This study examines three ant surveys at gopher tortoise burrows within a section of residential “greenway” in southeastern Florida before and after “reduction mowing”. While the presence of S. invicta did decrease aftrer the reduction mowing, the numbers of native ants and ant species richness in general showed a significant decline. Another invasive ant, the Little Fire Ant, Wasmannia auropunctata (Roger, 1863), showed a significant increase after the mowing. While not as destructive as S. invicta, W.auropunctata has been documented to be a significant pest to many terrestrial vertebrates and should be considered a potential threat in future gopher tortoise and land management schemes.
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Date Issued: 2013
PURL: http://purl.flvc.org/fau/fd/FA00003519
Format: Document (PDF)

Title: Demographic Survey of Gopherus polyphemus (Gopher Tortoise) at the Abacoa Greenway.
Creator: Sano, Tokio, Moore, Jon, Wetterer, James K., Harriet L. Wilkes Honors College
Abstract/Description: The Abacoa Greenway reserve is a 105 ha preserve in Jupiter, Florida. We investigated the demographics of the gopher tortoise population and their burrow distributions in a 9 ha portion of the greenway (Range VIa) used for the relocation of gopher tortoises. Range VIa currently houses at least 90 tortoises. According to state guidelines this reserve is considered to be a “support population” with ≤250 individuals living in an area ≤100 ha. We found that the tortoises in the reserve are...
Show moreThe Abacoa Greenway reserve is a 105 ha preserve in Jupiter, Florida. We investigated the demographics of the gopher tortoise population and their burrow distributions in a 9 ha portion of the greenway (Range VIa) used for the relocation of gopher tortoises. Range VIa currently houses at least 90 tortoises. According to state guidelines this reserve is considered to be a “support population” with ≤250 individuals living in an area ≤100 ha. We found that the tortoises in the reserve are showing signs of maturity at a younger age (7-10 years) and a larger size (25-35 cm carapace length) compared to more northern populations. We hypothesize that this is due to the latitudinal climate effects and warm winters allowing year-round foraging. For the gopher tortoise burrow distribution, we found that many tortoises are creating new burrows on the periphery due to the overgrowth of the vegetation in the interior of the reserve and a reduction mowing is needed.
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Date Issued: 2014
PURL: http://purl.flvc.org/fau/fd/FA00003625
Format: Document (PDF)

Title: LONG-TERM EFFECTS OF PRE-NATAL OXYCODONE EXPOSURE IN MICE.
Creator: Skaf, Daniel, Wetterer, James K., Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: Prescription drug abuse is a rapidly emerging epidemic. One serious consequence of this abuse is increased incidence of neonatal abstinence syndrome (NAS). NAS results from a pregnant mother abusing opiates during her gestation period. The short-term effects of in utero opiate exposure on newborns are well documented, but the long-term impacts are poorly known. Our project in the Miller Lab aimed to characterize the impacts of prenatal opiate exposure on the behavior of mice. Our data...
Show morePrescription drug abuse is a rapidly emerging epidemic. One serious consequence of this abuse is increased incidence of neonatal abstinence syndrome (NAS). NAS results from a pregnant mother abusing opiates during her gestation period. The short-term effects of in utero opiate exposure on newborns are well documented, but the long-term impacts are poorly known. Our project in the Miller Lab aimed to characterize the impacts of prenatal opiate exposure on the behavior of mice. Our data indicates that mice exposed to oxycodone in utero show abnormal, impulsive-like behavior and had a lower seizure threshold compared to control mice. We can now work towards identifying possible underlying brain structural abnormalities producing this phenotype, and we are now more prepared to deal with the lifelong impact of this exposure.
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Date Issued: 2017
PURL: http://purl.flvc.org/fau/fd/FA00012638
Format: Document (PDF)

Title: CELLULAR SENESCENCE INCREASES IN THE ERCC1-/Δ MOUSE MODEL OF ACCELERATED AGING.
Creator: Bukata, Christina, Wetterer, James K., Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: Aging is the result of the progressive and intrinsic accumulation of detrimental changes in an organism over time. Understanding the molecular pathways that contribute to aging is critical for the development of therapeutic agents to treat age-related disorders. As an animal ages, it accumulates senescent cells, cells that are unable to grow or divide but remain metabolically active. They secrete Senescence Associated Secretory Phenotype (SASP) factors, which can disrupt tissue and cause age...
Show moreAging is the result of the progressive and intrinsic accumulation of detrimental changes in an organism over time. Understanding the molecular pathways that contribute to aging is critical for the development of therapeutic agents to treat age-related disorders. As an animal ages, it accumulates senescent cells, cells that are unable to grow or divide but remain metabolically active. They secrete Senescence Associated Secretory Phenotype (SASP) factors, which can disrupt tissue and cause age related diseases. The Ercc1-/Δ mice are an accelerated aging, progeriod model, and thus it was hypothesized that cellular senescence would increase in the Ercc1-/Δ mice. Through quantitative polymerase chain reaction (qPCR) analysis, the expression of senescence biomarkers p16INK4a, p21, IL-6 and TNF-α were measured to confirm that Ercc1-/Δ mice do experience an increase in cellular senescence. Additionally, we were able to determine that there are gender differences regarding the accumulation of senescent cells in various body parts.
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Date Issued: 2017
PURL: http://purl.flvc.org/fau/fd/FA00012609
Format: Document (PDF)

Title: HOW TO IMPROVE THE DIETS OF COLLEGE STUDENTS.
Creator: Capi, Donald, Wetterer, James K., Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: Numerous studies have found a significant correlation between diet and brain function in humans and other animals, indicating that a healthy diet can greatly enhance cognition and reduce oxidative stress, which impairs brain health. My thesis examines the policies of ten successful university nutrition programs in the United States, with the aim of improving nutrition for students at the Wilkes Honors College, Florida Atlantic University (FAU). I proposed that FAU should establish an on-...
Show moreNumerous studies have found a significant correlation between diet and brain function in humans and other animals, indicating that a healthy diet can greatly enhance cognition and reduce oxidative stress, which impairs brain health. My thesis examines the policies of ten successful university nutrition programs in the United States, with the aim of improving nutrition for students at the Wilkes Honors College, Florida Atlantic University (FAU). I proposed that FAU should establish an on- campus vegetable garden, partner with local fisheries to provide fresh fish to the campus dining room, and mandate that all freshman complete a course in “nutrition for cognition.”
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Date Issued: 2016
PURL: http://purl.flvc.org/fau/fd/FA00012601
Format: Document (PDF)

Title: Anti-Bacterial Properties in Venom of Albanian Acrobat Ants, Crematogaster schmidti.
Creator: Sawai, Guillermo G., Wetterer, James K., Harriet L. Wilkes Honors College
Abstract/Description: Bioprospecting’s main goal is to discover natural compounds with beneficial properties. Previous studies have shown diverse, bio-active organic compounds found in the venom of different species of ants. In my research, I tested the venom of an acrobat ant from Albania, Crematogaster schmidti, for anti-bacterial properties by using the disc diffusion method. I found a decrease in bacterial colony growth where the venom was applied onto the agar plate.
Date Issued: 2016
PURL: http://purl.flvc.org/fau/fd/FA00003692
Format: Document (PDF)

Title: AUTOPHAGY IN DNA DAMAGE INDUCED ACCELERATED AGING.
Creator: Muravia, Mariya, Wetterer, James K., Florida Atlantic University, Harriet L. Wilkes Honors College
Abstract/Description: Autophagy, the cellular “recycling system” of unnecessary components, is a crucial mechanism for maintaining homeostasis inside the cell. Whereas impaired DNA repair function leads to accelerated aging and an early onset of several age-related diseases, it is not known whether autophagy plays a mediating role in this process. Here, we examined changes in autophagy in cells with progeria due to a disabled ERCC1-XPF, a nuclear DNA repair enzyme. We found that loss of ERCC1 function leads to DNA...
Show moreAutophagy, the cellular “recycling system” of unnecessary components, is a crucial mechanism for maintaining homeostasis inside the cell. Whereas impaired DNA repair function leads to accelerated aging and an early onset of several age-related diseases, it is not known whether autophagy plays a mediating role in this process. Here, we examined changes in autophagy in cells with progeria due to a disabled ERCC1-XPF, a nuclear DNA repair enzyme. We found that loss of ERCC1 function leads to DNA damage and a decrease in autophagic flux in cells. Low dose treatment with Rapamycin, an autophagy inducer, improved proliferation and delayed aging, or cellular senescence, in the cells. These data suggest that persistent DNA damage suppresses autophagic flux, thus contributing to early senescence and accelerated onset of age-related diseases. Therefore, therapeutics that improve autophagic flux, may prove beneficial for progeroid patients.
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Date Issued: 2017
PURL: http://purl.flvc.org/fau/fd/FA00012630
Format: Document (PDF)

Title: Cetacean Mortality Along the US East Coast Attributed to Morbillivirus.
Creator: Feliciano, Lyly, Wetterer, James K., Arrieta, Diane, Harriet L. Wilkes Honors College
Abstract/Description: In 2013-2014, bottlenose dolphins (Tursiops truncatus) experienced unusually high mortality along the East Coast of the US. Many deaths were attributed to Cetacean Morbillivirus (CeMV). My thesis research examined whether this high mortality could be attributed to the virus spreading more easily due to pollution, being picked up from a specific location, or unusual weather events. I found no evidence that pollutants or location corresponded with CeMV. There was the expected percentage of...
Show moreIn 2013-2014, bottlenose dolphins (Tursiops truncatus) experienced unusually high mortality along the East Coast of the US. Many deaths were attributed to Cetacean Morbillivirus (CeMV). My thesis research examined whether this high mortality could be attributed to the virus spreading more easily due to pollution, being picked up from a specific location, or unusual weather events. I found no evidence that pollutants or location corresponded with CeMV. There was the expected percentage of strandings based on the percentage of coastline therefore ruling out any linkage to location. Weather patterns appeared to have an effect on CeMV. When the temperatures were low, there were minimal strandings due to CeMV. Whereas, when temperatures were at their highest, there were also record numbers of CeMV. Thus, I concluded that high temperatures may have allowed increased spread of CeMV, which was compounded by increased movement of dolphins when waters are warmer.
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Date Issued: 2016
PURL: http://purl.flvc.org/fau/fd/FA00003672
Format: Document (PDF)

Title: Using C. elegans as a Model System to Discover Antiepileptic Drugs.
Creator: Merritt, Mckenzie D., Wetterer, James K., Harriet L. Wilkes Honors College
Abstract/Description: Novel antiepileptic drugs (AEDs) are commonly tested using rats and mice as model systems. These animals, however, require a great deal of time, money, and lab space to maintain. In contrast, the nematode Caenorhabditis elegans (C. elegans) potentially can provide a faster, and less expensive model system for testing AEDs. C. elegans are simple to maintain and have a very short generation time, allowing high throughput assays to screen for new AEDs. For my thesis research, I used C. elegans...
Show moreNovel antiepileptic drugs (AEDs) are commonly tested using rats and mice as model systems. These animals, however, require a great deal of time, money, and lab space to maintain. In contrast, the nematode Caenorhabditis elegans (C. elegans) potentially can provide a faster, and less expensive model system for testing AEDs. C. elegans are simple to maintain and have a very short generation time, allowing high throughput assays to screen for new AEDs. For my thesis research, I used C. elegans to test FDA approved AEDs. My tests support the contention that C. elegans can be a useful model system for AED discovery.
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Date Issued: 2016
PURL: http://purl.flvc.org/fau/fd/FA00003682
Format: Document (PDF)

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