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Collections of marine organisms for research on natural products chemistry and biodiversity: A survey of the benthic communities with emphasis on porifera, octocorals, and algae from the reefs and grassbeds of Bootless Bay, Papua New Guinea
Total synthesis of a library of designed hybrids of the microtubule-stabilising anticancer agents taxol, discodermolide and dictyostatin
The microtubule-stabilizing agent discodermolide competitively inhibits the binding of paclitaxel (Taxol) to tubulin polymers, enhances tubulin nucleation reactions more potently than paclitaxel, and inhibits the growth of paclitaxel-resistant cells.
Marine organisms as a source of novel lead structures for drug development
Total synthesis of a potent hybrid of the anticancer natural products dictyostatin and discodermolide.
Early effects of Lasonolide A on pancreatic cancer cells
Selective cytotoxic activity of the marine derivedbatzelline compounds against pancreatic cancer cell lines
Maximizing the potential of marine organism collections for both pharmacological and systematic studies
Antitumor activity and nucleic acid binding properties of Dercitin, a new acridinealkaloid isolated from a marine dercitus species sponge
In vitro production of marine-derived antitumor compounds
The oceans and human health: the discovery and development of marine-derived drugs
Discodermolide- a new, marine-derived immunosuppressive compound. I.In vitro studies
Discodermolide-a new, marine-derived immunosuppressive compound. II.In vivo studies
The chemistry and biological activity of five marine sponges of the genus Aplysina
Development of techniques for in vitro production of bioactive natural products from marine sponges
Antitumoractivity and mechanism of action of the novel marine natural products mycalamide-A and -B andonnamide
Sustainable use of deep-sea organisms collected for biomedical research
Isolation of marine natural products
Bioactivity of marine organisms: relationships with taxonomy, geography and depth
The discovery of marine natural products with therapeutic potential

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