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ANALYSIS OF MENTHOL EXTRACTED FROM MINT LEAVES USING VCD AND COMPUTATION GENERATED SPECTRA

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Date Issued:
2022
Abstract/Description:
Recently, the terpene class of molecules have been under much interest due to their potential medicinal properties. Terpenes such as cannabidiol and tetrahydrocannabinol have been studied for their psychological effects, while others like myrcene are of interest due to their antifungal and antibacterial properties. However, some of these terpenes possess different properties dependent on their stereochemistry, potentially with one enantiomer having the desired the effect and the other having a reduced or even harmful effect in some cases. Despite the importance of stereochemistry in medicine, techniques that are sensitive to it are still uncommon, but one technique in the form of VCD/IR spectroscopy has been under interest due to its ability to effectively analyze small molecules with limited flexibility, such as many terpenes. This thesis will cover the use of VCD/IR spectroscopy in the analysis of menthol from Mentha piperita, specifically the stereochemistry based on a known pure sample, and through calculated spectra.
Title: ANALYSIS OF MENTHOL EXTRACTED FROM MINT LEAVES USING VCD AND COMPUTATION GENERATED SPECTRA.
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Name(s): Xu, Ethan, author
Chandrasekhar, Chitra , Thesis advisor
Harriet L. Wilkes Honors College
Florida Atlantic University, Degree grantor
Type of Resource: text
Genre: Thesis
Date Created: 2022
Date Issued: 2022
Publisher: Florida Atlantic University
Place of Publication: Jupiter, Florida
Physical Form: application/pdf
Extent: 46 p.
Language(s): English
Abstract/Description: Recently, the terpene class of molecules have been under much interest due to their potential medicinal properties. Terpenes such as cannabidiol and tetrahydrocannabinol have been studied for their psychological effects, while others like myrcene are of interest due to their antifungal and antibacterial properties. However, some of these terpenes possess different properties dependent on their stereochemistry, potentially with one enantiomer having the desired the effect and the other having a reduced or even harmful effect in some cases. Despite the importance of stereochemistry in medicine, techniques that are sensitive to it are still uncommon, but one technique in the form of VCD/IR spectroscopy has been under interest due to its ability to effectively analyze small molecules with limited flexibility, such as many terpenes. This thesis will cover the use of VCD/IR spectroscopy in the analysis of menthol from Mentha piperita, specifically the stereochemistry based on a known pure sample, and through calculated spectra.
Identifier: FAUHT00225 (IID)
Degree granted: Thesis (B.S.)--Florida Atlantic University, Harriet L. Wilkes Honors College, 2022
Persistent Link to This Record: http://purl.flvc.org/fau/fd/FAUHT00225
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Host Institution: FAU
Is Part of Series: Florida Atlantic University Digital Library Collections.

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