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GFAP-Based Gene Therapy for Treatment of Retinal Diseases, 2008

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Date Issued:
2008
Abstract/Description:
Compositions and methods for reducing neovascularization. Purified nucleic acid constructs and vectors encoding an antiangiogenic protein operably linked to a GFAP promoter. Vectors can include at least one hypoxia regulated element, enhancer element and silencer element. Gene therapy methods for reducing, delaying or preventing neovascularization based on the nucleic acid constructs and vectors.
Title: GFAP-Based Gene Therapy for Treatment of Retinal Diseases, 2008.
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Name(s): Dorey, C. Kathleen, author
Blanks, Janet C.
Florida Atlantic University
Prentice, Howard
Type of Resource: text
Genre: Patent
Date Created: 2008
Date Issued: 2008
Publisher: Florida Atlantic University
Place of Publication: Boca Raton, FL
Physical Form: application/pdf
Extent: 28 p.
Language(s): English
Abstract/Description: Compositions and methods for reducing neovascularization. Purified nucleic acid constructs and vectors encoding an antiangiogenic protein operably linked to a GFAP promoter. Vectors can include at least one hypoxia regulated element, enhancer element and silencer element. Gene therapy methods for reducing, delaying or preventing neovascularization based on the nucleic acid constructs and vectors.
Identifier: FAUIR000259 (IID)
Persistent Link to This Record: http://purl.flvc.org/fau/fd/FAUIR000259
Use and Reproduction: All rights reserved by the source institution
Host Institution: FAU