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THE DEVELOPMENT OF WIDE-FIELD BIO-IMAGING FOR POINT OF CARE DIAGNOSTIC ASSAYS IN RESOURCE CONSTRAINED SETTINGS

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Date Issued:
2021
Abstract/Description:
The World Health Organization has identified the need for affordable, specific, rapid and deliverable point of care assays for infectious diseases in areas that are resource poor and lacking readily available complex testing methods. The objective of this research is to discover improved methods of capturing and counting CD4+T, in a portable assay to aid in the detection of HIV or other diseases that are informed by cell identification and count. The research divides into 4 major objectives: Design an improved portable, microchip. to isolate cells in a timely manner. Explore, design and prove the optical technology that provides large field-of-view and enables imaging large surface area simultaneously so that a sufficient sample can be collected. Test and analyze the microchip and optics to verify the specificity and efficiency of the biological process. Identify and count the cells in an automated manner.
Title: THE DEVELOPMENT OF WIDE-FIELD BIO-IMAGING FOR POINT OF CARE DIAGNOSTIC ASSAYS IN RESOURCE CONSTRAINED SETTINGS.
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Name(s): Fennell, Robert , author
Asghar, Waseem, Thesis advisor
Florida Atlantic University, Degree grantor
Department of Computer and Electrical Engineering and Computer Science
College of Engineering and Computer Science
Type of Resource: text
Genre: Electronic Thesis Or Dissertation
Date Created: 2021
Date Issued: 2021
Publisher: Florida Atlantic University
Place of Publication: Boca Raton, Fla.
Physical Form: application/pdf
Extent: 114 p.
Language(s): English
Abstract/Description: The World Health Organization has identified the need for affordable, specific, rapid and deliverable point of care assays for infectious diseases in areas that are resource poor and lacking readily available complex testing methods. The objective of this research is to discover improved methods of capturing and counting CD4+T, in a portable assay to aid in the detection of HIV or other diseases that are informed by cell identification and count. The research divides into 4 major objectives: Design an improved portable, microchip. to isolate cells in a timely manner. Explore, design and prove the optical technology that provides large field-of-view and enables imaging large surface area simultaneously so that a sufficient sample can be collected. Test and analyze the microchip and optics to verify the specificity and efficiency of the biological process. Identify and count the cells in an automated manner.
Identifier: FA00013817 (IID)
Degree granted: Dissertation (Ph.D.)--Florida Atlantic University, 2021.
Collection: FAU Electronic Theses and Dissertations Collection
Note(s): Includes bibliography.
Subject(s): Point-of-care testing
HIV
Persistent Link to This Record: http://purl.flvc.org/fau/fd/FA00013817
Use and Reproduction: Copyright © is held by the author with permission granted to Florida Atlantic University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder.
Use and Reproduction: http://rightsstatements.org/vocab/InC/1.0/
Host Institution: FAU
Is Part of Series: Florida Atlantic University Digital Library Collections.