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Postnatal development of brainstem gustatory pathways: Development of protein P-38 immunoreactivity and myelination of chorda tympani axons
| Title: | Postnatal development of brainstem gustatory pathways: Development of protein P-38 immunoreactivity and myelination of chorda tympani axons. |
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| Name(s): |
Kachele, Diane L. Florida Atlantic University, Degree Grantor Charles E. Schmidt College of Science Department of Psychology |
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| Type of Resource: | text | |
| Genre: | Electronic Thesis Or Dissertation | |
| Issuance: | monographic | |
| Date Issued: | 1989 | |
| Publisher: | Florida Atlantic University | |
| Place of Publication: | Boca Raton, Fla. | |
| Physical Form: | application/pdf | |
| Extent: | 73 p. | |
| Language(s): | English | |
| Summary: | Previous studies conducted in this lab have shown that morphological changes occur in postsynaptic elements of brainstem gustatory relays during rat's postnatal life. Dendritic length and mitochondrial respiratory enzyme activity increase in the rostral nucleus of the solitary tract (NST) and in the caudal parabrachial nucleus (PBN). These increases are well-related to certain aspects of neurophysiological development in the NST and PBN. Other factors are known to contribute to the development of neurophysiological responses, such as synapse formation and myelination of axons. The present study examined developmental increases in protein P-38 immunoreactivity. Protein P-38 ("Synaptophysin") is a specific integral membrane protein found in small, clear synaptic vesicles. In addition, the time-course for myelination of central chorda tympani (CT) axons was investigated. Results demonstrate that P-38 immunoreactivity increases in the NST and PBN in a temporally-sequential manner during postnatal development. Reliable increases in P-38 immunoreactivity are observed between postnatal days 1 and 10 (P1-P10) in the rostral NST, whereas density of reaction products in the PBN increases from P11-P31. The time-course for myelination of chorda tympani (CT) axons within the medulla does not differ from the time-course for myelination of CT axons in the periphery. These studies confirm that both pre- and postsynaptic constituents of brainstem gustatory relays develop in a temporally-sequential manner. Relationships between these neurological changes and the ontogeny of adult-like taste-guided responses are discussed. | |
| Identifier: | 11932 (digitool), FADT11932 (IID), fau:8851 (fedora) | |
| Collection: | FAU Electronic Theses and Dissertations Collection | |
| Note(s): | Thesis (Ph.D.)--Florida Atlantic University, 1989. | |
| Subject(s): | Psychology, Psychobiology | |
| Held by: | Florida Atlantic University Libraries | |
| Persistent Link to This Record: | http://purl.flvc.org/fcla/dt/11932 | |
| Sublocation: | Digital Library | |
| Use and Reproduction: | Copyright © is held by the author, with permission granted to Florida Atlantic University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder. | |
| Use and Reproduction: | http://rightsstatements.org/vocab/InC/1.0/ | |
| Host Institution: | FAU | |
| Is Part of Series: | Florida Atlantic University Digital Library Collections. |
