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Inhibition of murine lymphokine-activated killer (LAK) cell activity by adherent cells
| Title: | Inhibition of murine lymphokine-activated killer (LAK) cell activity by adherent cells. |
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| Name(s): |
Longley, Ross E., creator Stewart, D., creator Roe, K. G., creator Good, R. A., creator Harbor Branch Oceanographic Institute |
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| Type of Resource: | text | |
| Genre: | Article | |
| Issuance: | single unit | |
| Date Issued: | 1989 | |
| Publisher: | Elsevier B.V. | |
| Extent: | 13 p. | |
| Physical Description: | ||
| Language(s): | English | |
| Identifier: | 3353831 (digitool), FADT3353831 (IID), fau:6636 (fedora), 10.1016/0008-8749(89)90021-X (doi) | |
| Note(s): |
The effects of adherent cell depletion, indomethacin, and prostaglandin E2 (PGE2) on murine LAK cell activity were investigated. Removal of plastic adherent cells from splenocyte suspensions either prior to 5-day culture with 1000 U/ml of recombinant human IL-2 (rIL-2) or prior to assay resulted in an enhanced LAK cell cytotoxicity compared to that of whole spleen cell suspensions. Indomethacin enhanced LAK cell cytotoxicity of whole splenocyte suspensions if present during the culture period, but had no effect on whole splenocyte or adherent cell-depleted cell suspensions if added just prior to assay. The final published version of this manuscript is available at http://www.sciencedirect.com/science/journal/00088749 and may be cited as: Longley, R. E., Stewart, D., Roe, K. G., & Good, R. A. (1989). Inhibition of murine lymphokine-activated killer (LAK) cell activity by adherent cells. Cellular Immunology, 121(2), 225-236. doi:10.1016/0008-8749(89)90021-X Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #703. |
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| Subject(s): |
Killer Cells, Lymphokine-Activated Indomethacin Dinoprostone Immunotherapy Spleen |
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| Persistent Link to This Record: | http://purl.flvc.org/FCLA/DT/3353831 | |
| Links: | http://dx.doi.org/10.1016/0008-8749(89)90021-X | |
| Restrictions on Access: | ©1989 Elsevier B.V. | |
| Host Institution: | FAU |
