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Antitumor cyclic peroxides from the sponge Plakortis lita
| Title: | Antitumor cyclic peroxides from the sponge Plakortis lita. |
 98 views 22 downloads |
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| Name(s): |
Sakemi, S., creator Higa, T., creator Anthoni, U., creator Christophersen, C., creator Harbor Branch Oceanographic Institute |
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| Type of Resource: | text | |
| Genre: | Article | |
| Issuance: | single unit | |
| Date Issued: | 1987 | |
| Publisher: | Elsevier | |
| Extent: | 7 p. | |
| Physical Description: | ||
| Language(s): | English | |
| Identifier: | 3353800 (digitool), FADT3353800 (IID), fau:6620 (fedora), 10.1016/S0040-4020(01)89953-1 (doi) | |
| Note(s): |
Four new cyclic peroxides (5–8) along with known chondrillin (4) have been isolated as antitumor constituents of the sponge Plakortis lita. These are methyl-(3S*, 6S*)-3, 6-epidioxy- 6-methoxyoctadec-4-enoate (5), methyl( 3S*, 6S*, 16E)-3, 6-epidoxy- 6-methoxyoctadeca-4,16-dienoate (6), methyl( 3S*, 6S*, 14E, 16E)- 3, 6-epidioxy-6-methoxyoctadeca-4, 14, 16-trienoate (7), and methyl-( 3S*, 6S*, 16E, 18E)-3, 6-epidioxy-6-methoxyeicosa-4 ,16 ,18- trinoate (8). All of them are epimeric to 4 and exhibit higher antitumor potency than 4. The final published version of this manuscript is available at http://www.sciencedirect.com/science/journal/00404020 and may be cited as: Sakemi, S., Higa, T., Anthoni, U., & Christophersen, C. (1987). Antitumor cyclic peroxides from the sponge Plakortis lita. Tetrahedron, 43(1), 263-268. doi:10.1016/S0040-4020(01)89953-1 Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #577. |
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| Subject(s): |
Antineoplastic agents Sponges Peroxides Marine metabolites |
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| Persistent Link to This Record: | http://purl.flvc.org/FCLA/DT/3353800 | |
| Links: | http://dx.doi.org/10.1016/S0040-4020(01)89953-1 | |
| Restrictions on Access: | ©1987 Elsevier Ltd. | |
| Host Institution: | FAU |
