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Cytotoxin production by a marine Lyngbya strain (cyanobacterium) in a large-scale laboratory bioreactor

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Date Issued:
1991
Title: Cytotoxin production by a marine Lyngbya strain (cyanobacterium) in a large-scale laboratory bioreactor.
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Name(s): Armstrong, J. E., creator
Janda, Kathleen E., creator
Alvarado, B., creator
Wright, Amy E., creator
Type of Resource: text
Genre: Article
Issuance: single unit
Date Issued: 1991
Publisher: Springer
Extent: 7 p.
Physical Description: pdf
Language(s): English
Identifier: 3333194 (digitool), FADT3333194 (IID), fau:6276 (fedora), 10.1007/BF00003586 (doi)
Note(s): A cytotoxic compound was produced by the marine cyanobacterium Lyngbya sp. Pearl strain in large laboratory-scale batch cultures. Adsorption and fractionation of methanol extracts with reverse phase (C-18) cartridges provided a rapid method for removal of bioassay interference from salts, biopolymers and pigments and concentration of the cytotoxic principles. Cytotoxicity to the murine leukemia cell line P-388 was produced in two cycles coinciding with the initiation of exponential growth and again during the late exponential growth phase.
This manuscript is an author version with the final publication available at http://www.springerlink.com and may be cited as: Armstrong, J. E., Janda, K. E., Alvarado, B., & Wright, A. E. (1991). Cytotoxin production by a marine Lyngbya strain (cyanobacterium) in a large-scale laboratory bioreactor. Journal of Applied Phycology, 3(3), 277-282. doi:10.1007/BF00003586
Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #853.
Subject(s): Lyngbya
Cyanobacteria
Cytotoxin
Bioreactors
Persistent Link to This Record: http://purl.flvc.org/FCLA/DT/3333194
Links: http://dx.doi.org/10.1007/BF00003586
Restrictions on Access: ©1991 Springer
Host Institution: FAU