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Cytotoxin production by a marine Lyngbya strain (cyanobacterium) in a large-scale laboratory bioreactor
- Date Issued:
- 1991
Title: | Cytotoxin production by a marine Lyngbya strain (cyanobacterium) in a large-scale laboratory bioreactor. |
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Name(s): |
Armstrong, J. E., creator Janda, Kathleen E., creator Alvarado, B., creator Wright, Amy E., creator |
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Type of Resource: | text | |
Genre: | Article | |
Issuance: | single unit | |
Date Issued: | 1991 | |
Publisher: | Springer | |
Extent: | 7 p. | |
Physical Description: | ||
Language(s): | English | |
Identifier: | 3333194 (digitool), FADT3333194 (IID), fau:6276 (fedora), 10.1007/BF00003586 (doi) | |
Note(s): |
A cytotoxic compound was produced by the marine cyanobacterium Lyngbya sp. Pearl strain in large laboratory-scale batch cultures. Adsorption and fractionation of methanol extracts with reverse phase (C-18) cartridges provided a rapid method for removal of bioassay interference from salts, biopolymers and pigments and concentration of the cytotoxic principles. Cytotoxicity to the murine leukemia cell line P-388 was produced in two cycles coinciding with the initiation of exponential growth and again during the late exponential growth phase. This manuscript is an author version with the final publication available at http://www.springerlink.com and may be cited as: Armstrong, J. E., Janda, K. E., Alvarado, B., & Wright, A. E. (1991). Cytotoxin production by a marine Lyngbya strain (cyanobacterium) in a large-scale laboratory bioreactor. Journal of Applied Phycology, 3(3), 277-282. doi:10.1007/BF00003586 Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #853. |
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Subject(s): |
Lyngbya Cyanobacteria Cytotoxin Bioreactors |
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Persistent Link to This Record: | http://purl.flvc.org/FCLA/DT/3333194 | |
Links: | http://dx.doi.org/10.1007/BF00003586 | |
Restrictions on Access: | ©1991 Springer | |
Host Institution: | FAU |