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New antiviral sterol disulfate ortho esters from the marine sponge Petrosia weinbergi
| Title: | New antiviral sterol disulfate ortho esters from the marine sponge Petrosia weinbergi. |
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| Name(s): |
Koehn, F. E., creator Gunasekera, M., creator Cross, S. S., creator Harbor Branch Oceanographic Institute |
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| Type of Resource: | text | |
| Genre: | Article | |
| Issuance: | single unit | |
| Date Issued: | 1991 | |
| Publisher: | American Chemical Society | |
| Extent: | 5 p. | |
| Physical Description: | ||
| Language(s): | English | |
| Identifier: | 3332977 (digitool), FADT3332977 (IID), fau:6191 (fedora), 10.1021/jo00003a080 (doi) | |
| Note(s): |
During our ongoing program to isolate novel antiviral marine natural products, we have found that extracts of the marine sponge Petrosia weinbergi show in vitro activity against feline leukemia virus (FELV), mouse influenza virus (PR8), and mouse coronavirus (A59).3 We report here the isolation and structure elucidation of orthoesterol disulfates A (1a), B (1b), and C (1C), three new antiviral sterol disulfate ortho esters. We believe these to be the first reported examples in the steroid class of this particular combination of functionalities. This document is the accepted manuscript version of a published work that appeared in final form in The Journal of Organic Chemistry after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/jo00003a080. This article may be cited as: Koehn, F. E., Gunasekera, M., & Cross, S. S. (1991). New antiviral sterol disulfate ortho esters from the marine sponge Petrosia weinbergi. The Journal of Organic Chemistry, 56(3), 1322-1325. doi:10.1021/jo00003a080 Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #811. |
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| Subject(s): |
Sponges Sterols Marine natural products Antiviral agents |
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| Persistent Link to This Record: | http://purl.flvc.org/FCLA/DT/3332977 | |
| Links: | http://dx.doi.org/10.1021/jo00003a080 | |
| Restrictions on Access: | ©1991 American Chemical Society | |
| Host Institution: | FAU |
