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Two new bioactive cyclic peroxides from the marine sponge Plakortis angulospiculatus
| Title: | Two new bioactive cyclic peroxides from the marine sponge Plakortis angulospiculatus. |
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| Name(s): |
Gunasekera, Sarath P., creator Gunasekera, M., creator Gunawardana, G. P., creator McCarthy, Peter J., creator Burres, N. S., creator |
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| Type of Resource: | text | |
| Genre: | Article | |
| Issuance: | single unit | |
| Date Issued: | 1990 | |
| Publisher: | The American Chemical Society and American Society of Pharmacognosy | |
| Extent: | 7 p. | |
| Physical Description: | ||
| Language(s): | English | |
| Identifier: | 3332965 (digitool), FADT3332965 (IID), fau:6185 (fedora), 10.1021/np50069a021 (doi) | |
| Note(s): |
Two new antifungal and cytotoxic cyclic-peroxide-containing acids, 1 and 3, were isolated from a marine sponge, Plakortis angulospiculatus, which was collected by scuba off the coast of Venezuela. The structures were elucidated through spectral and chemical analysis of the corresponding methyl esters, 2 and 4. The acids are potent cytotoxic and antifungal agents although their esters are only cytotoxic. This document is the accepted manuscript version of a published work that appeared in final form in Journal of Natural Products after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/np50069a021. This article may be cited as: Gunasekera, S. P., Gunasekera, M., Gunawardana, G. P., McCarthy, P., & Burres, N. (1990). Two new bioactive cyclic peroxides from the marine sponge Plakortis angulospiculatus. Journal of Natural Products, 53(3), 669-674. doi:10.1021/np50069a021 Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #757. |
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| Subject(s): |
Sponges Peroxides Bioactive compounds Antifungal agents Cytotoxin Marine metabolites |
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| Persistent Link to This Record: | http://purl.flvc.org/FCLA/DT/3332965 | |
| Links: | http://dx.doi.org/10.1021/np50069a021 | |
| Restrictions on Access: | The American Chemical Society and American Society of Pharmacognosy | |
| Host Institution: | FAU |
