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Brianthein V, a new cytotoxic and antiviral diterpene isolated from Briareum asbestinum

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Date Issued:
1988
Title: Brianthein V, a new cytotoxic and antiviral diterpene isolated from Briareum asbestinum.
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Name(s): Coval, S. J., creator
Cross, S. S., creator
Bernardinelli, G., creator
Jefford, C. W., creator
Harbor Branch Oceanographic Institute
Type of Resource: text
Genre: Article
Issuance: single unit
Date Issued: 1988
Publisher: The American Chemical Society and American Society of Pharmacognosy
Extent: 5 p.
Physical Description: pdf
Language(s): English
Identifier: 3332954 (digitool), FADT3332954 (IID), fau:6179 (fedora), 10.1021/np50059a031 (doi)
Note(s): The gorgonian coral Briareum asbestinum (Pallas) (Briareidae), occurring in Caribbean waters, contains diterpenes of two skeletal types, the asbestinins and the briareins, some of which are endowed with biological activity (1, 2). Several chlorinated briareins have also been isolated, and the absolute structure of one of them, briarein A [1], a pentaacetate, has been determined by X-ray (3). Subsequently, a related species Briareum polyanthes, found off Bermuda, was examined. Three metabolites possessing the epoxybriarein structure, but designated as briantheins X [2], Y [3], and Z [4] were identified (4, 5). [The structure of Brianthein W, a less fuctionalized nonchlorinated briarein, has been recently determined (6).]
This document is the accepted manuscript version of a published work that appeared in final form in Journal of Natural Products after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/np50059a031. This article may be cited as: Coval, S. J., Cross, S., Bernardelli, G., & Jefford, C. W. (1988). Brianthein V, a new cytotoxic and antiviral diterpene isolated from Briareum asbestinum. Journal of Natural Products, 51(5), 981-984. doi.10.1021/np50059a031
Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #674.
Subject(s): Corals--Caribbean Sea
Gorgonacea
Diterpenes
Antiviral agents
Cytotoxin
Persistent Link to This Record: http://purl.flvc.org/FCLA/DT/3332954
Links: http://dx.doi.org/10.1021/np50059a031
Restrictions on Access: ©1988 The American Chemical Society and American Society of Pharmacognosy
Host Institution: FAU