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Brianthein V, a new cytotoxic and antiviral diterpene isolated from Briareum asbestinum
- Date Issued:
- 1988
Title: | Brianthein V, a new cytotoxic and antiviral diterpene isolated from Briareum asbestinum. |
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Name(s): |
Coval, S. J., creator Cross, S. S., creator Bernardinelli, G., creator Jefford, C. W., creator Harbor Branch Oceanographic Institute |
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Type of Resource: | text | |
Genre: | Article | |
Issuance: | single unit | |
Date Issued: | 1988 | |
Publisher: | The American Chemical Society and American Society of Pharmacognosy | |
Extent: | 5 p. | |
Physical Description: | ||
Language(s): | English | |
Identifier: | 3332954 (digitool), FADT3332954 (IID), fau:6179 (fedora), 10.1021/np50059a031 (doi) | |
Note(s): |
The gorgonian coral Briareum asbestinum (Pallas) (Briareidae), occurring in Caribbean waters, contains diterpenes of two skeletal types, the asbestinins and the briareins, some of which are endowed with biological activity (1, 2). Several chlorinated briareins have also been isolated, and the absolute structure of one of them, briarein A [1], a pentaacetate, has been determined by X-ray (3). Subsequently, a related species Briareum polyanthes, found off Bermuda, was examined. Three metabolites possessing the epoxybriarein structure, but designated as briantheins X [2], Y [3], and Z [4] were identified (4, 5). [The structure of Brianthein W, a less fuctionalized nonchlorinated briarein, has been recently determined (6).] This document is the accepted manuscript version of a published work that appeared in final form in Journal of Natural Products after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/np50059a031. This article may be cited as: Coval, S. J., Cross, S., Bernardelli, G., & Jefford, C. W. (1988). Brianthein V, a new cytotoxic and antiviral diterpene isolated from Briareum asbestinum. Journal of Natural Products, 51(5), 981-984. doi.10.1021/np50059a031 Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #674. |
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Subject(s): |
Corals--Caribbean Sea Gorgonacea Diterpenes Antiviral agents Cytotoxin |
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Persistent Link to This Record: | http://purl.flvc.org/FCLA/DT/3332954 | |
Links: | http://dx.doi.org/10.1021/np50059a031 | |
Restrictions on Access: | ©1988 The American Chemical Society and American Society of Pharmacognosy | |
Host Institution: | FAU |