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Isolation, synthesis, and biological activity of Aphrocallistin, an adenine-substituted bromotyramine metabolite from the hexactinellida sponge Aphrocallistes beatrix
| Title: | Isolation, synthesis, and biological activity of Aphrocallistin, an adenine-substituted bromotyramine metabolite from the hexactinellida sponge Aphrocallistes beatrix. |
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| Name(s): |
Wright, Amy E., creator Roth, G. P., creator Hoffman, J. K., creator Divlianska, D. B., creator Pechter, D., creator Sennett, Susan H., creator Guzman, Esther A., creator Linley, P. A., creator McCarthy, Peter J., creator Pitts, Tara P., creator Pomponi, Shirley A., creator Reed, John K., creator |
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| Type of Resource: | text | |
| Genre: | Article | |
| Issuance: | single unit | |
| Date Issued: | 2009 | |
| Publisher: | American Chemical Society and American Society of Pharmacognosy | |
| Extent: | 7 p. | |
| Physical Description: | ||
| Language(s): | English | |
| Identifier: | 3319109 (digitool), FADT3319109 (IID), fau:6045 (fedora), 10.1021/np900183v (doi) | |
| Note(s): |
A new adenine-substituted bromotyrosine-derived metabolite designated as aphrocallistin (1) has been isolated from the deep-water Hexactinellida sponge Aphrocallistes beatrix. Its structure was elucidated on the basis of spectral data and confirmed through a convergent, modular total synthetic route that is amenable toward future analogue preparation. This document is the accepted manuscript version of a published work that appeared in final form in Journal of Natural Products after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/np900183v. This article may be cited as: Wright, A. E., Roth, G. P., Hoffman, J. K., Divlianska, D. B., Pechter, D., Sennett, S. H., Guzman, E. A., Linley, P., McCarthy, P. J., Pitts, T. P., Pomponi, S. A., & Reed, J K. (2009). Isolation, synthesis, and biological activity of Aphrocallistin, an adenine-substituted bromotyramine metabolite from the hexactinellida sponge Aphrocallistes beatrix. Journal of Natural Products, 72(6), 1178-1183. doi:10.1021/np900183v Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #1733. |
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| Subject(s): |
Sponges --Research Marine metabolites Marine natural products Hexactinellida |
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| Persistent Link to This Record: | http://purl.flvc.org/FCLA/DT/3319109 | |
| Links: | http://dx.doi.org/10.1021/np900183v | |
| Restrictions on Access: | ©2009 American Chemical Society and American Society of Pharmacognosy | |
| Host Institution: | FAU |
