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The Kapakahines, cyclic peptides from the marine sponge Cribrochalina olemda

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Date Issued:
1996
Title: The Kapakahines, cyclic peptides from the marine sponge Cribrochalina olemda.
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Name(s): Yeung, Bryan K. S., creator
Nakao, Y., creator
Kinnel, R. B., creator
Carney, J. R., creator
Yoshida, W. Y., creator
Scheuer, P. J., creator
Harbor Branch Oceanographic Institute
Type of Resource: text
Genre: Article
Issuance: single unit
Date Issued: 1996
Publisher: American Chemical Society
Extent: 7 p.
Physical Description: pdf
Language(s): English
Identifier: 3319098 (digitool), FADT3319098 (IID), fau:6039 (fedora), 10.1021/jo960725e (doi)
Note(s): Four cyclic peptides, kapakahines A−D, were isolated from the marine sponge Cribrochalina olemda. Their structures including complete stereochemistry were elucidated by spectral analysis and chemical degradation. The unique structural feature of these peptides is the lack of an amide linkage between two tryptophan residues. Instead the ring is closed by a bond from the indole nitrogen of Trp-1 to the β-carbon of Trp-2.
This document is the accepted manuscript version of a published work that appeared in final form in Journal of Organic Chemistry after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/jo960725e. This article may be cited as: Young, B. K. S., Nakao, Y., Kinnel, R. B., Carney, J. R., Yoshida, W. Y., & Scheuer, P. J. (1996). The Kapakahines, cyclic peptides from the marine sponge Cribrochalina olemda. Journal of Organic Chemistry, 61(20), 7168-7173. doi:10.1021/jo960725e
Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #1163.
Subject(s): Sponges --Research
Marine natural products
Cyclic peptides
Persistent Link to This Record: http://purl.flvc.org/FCLA/DT/3319098
Links: http://dx.doi.org/10.1021/jo960725e
Restrictions on Access: ©1996 American Chemical Society
Host Institution: FAU