You are here
Aplysillin A, a thrombin receptor antagonist from the marine sponge, Aplysina fistularis fulva
| Title: | Aplysillin A, a thrombin receptor antagonist from the marine sponge, Aplysina fistularis fulva. |
 111 views 20 downloads |
|---|---|---|
| Name(s): |
Gulavita, N. K., creator Pomponi, Shirley A., creator Wright, Amy E., creator Garay, M., creator Sills, Matthew A., creator |
|
| Type of Resource: | text | |
| Genre: | Article | |
| Issuance: | single unit | |
| Date Issued: | 1995 | |
| Publisher: | American Chemical Society | |
| Extent: | 5 p. | |
| Physical Description: | ||
| Language(s): | English | |
| Identifier: | 3319084 (digitool), FADT3319084 (IID), fau:6032 (fedora), 10.1021/np50120a023 (doi) | |
| Note(s): |
Aplysillin A [1], an unusual disulfate ester of a 1,4-diphenyl-1,3-butadiene, was isolated from a deep water specimen of a sponge of the genus Aplysina. Its structure was determined through spectroscopic methods. The compound weakly inhibited binding to the thrombin receptor with an IC50 value of 20 microM. This document is the accepted manuscript version of a published work that appeared in final form in Journal of Natural Products after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/np50120a023. This article may be cited as: Gulavita, N. K., Pomponi, S. A., Wright, A. E., Garay, M., & Sills, M. A. (1995). Aplysillin A, a thrombin receptor antagonist from the marine sponge, Aplysina fistularis fulva. Journal of Natural Products, 58(6), 954-957. doi:10.1021/np50120a023 Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #1078. |
|
| Subject(s): |
Sponges --Research Marine natural products Receptors, Thrombin Aplysillin A Antagonists, Enzyme Marine pharmacology |
|
| Persistent Link to This Record: | http://purl.flvc.org/FCLA/DT/3319084 | |
| Links: | http://dx.doi.org/10.1021/np50120a023 | |
| Restrictions on Access: | ©1995 American Chemical Society | |
| Host Institution: | FAU |
