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Verongamine, a novel bromotyrosine derived histamine H3-antagonist from the marine sponge Verongula gigantea
| Title: | Verongamine, a novel bromotyrosine derived histamine H3-antagonist from the marine sponge Verongula gigantea. |
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| Name(s): |
Mierzwa, Ronald, creator King, Arthur, creator Conover, M. A., creator Tozzi, S., creator Puar, M. S., creator Patel, Mahesh, creator Coval, S. J., creator Pomponi, Shirley A., creator |
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| Type of Resource: | text | |
| Genre: | Article | |
| Issuance: | single unit | |
| Date Issued: | 1994 | |
| Publisher: | American Chemical Society | |
| Extent: | 4 p. | |
| Physical Description: | ||
| Language(s): | English | |
| Identifier: | 3318974 (digitool), FADT3318974 (IID), fau:6024 (fedora), 10.1021/np50103a029 (doi) | |
| Note(s): |
The novel bromotyrosine derivative verongamine [1] has been isolated from the marine sponge Verongula gigantea. The isolation of verongamine was facilitated by employing histamine-H3 bioassay-guided fractionation. Verongamine is a specific histamine-H3 antagonist at concentrations as low as 1 microgram/ml. This document is the accepted manuscript version of a published work that appeared in final form in Journal of Natural Products after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/np50103a029. This article may be cited as: Mierzwa, R., King, A., Conover, M. A., Tozzi, S., Puar, M. S., Patel, M., Coval, S. J., & Pomponi, S. A. (1994). Verongamine, a novel bromotyrosine derived histamine H3-antagonist from the marine sponge Verongula gigantea. Journal of Natural Products, 57(1), 175-177. doi:10.1021/np50103a029 Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #993. |
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| Subject(s): |
Sponges --Research Marine natural products Drug Discovery |
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| Persistent Link to This Record: | http://purl.flvc.org/FCLA/DT/3318974 | |
| Links: | http://dx.doi.org/10.1021/np50103a029 | |
| Restrictions on Access: | ©1994 American Chemical Society | |
| Host Institution: | FAU |
