You are here
Evaluation of marine sponge metabolites for cytotoxicity and signal transduction activity
| Title: | Evaluation of marine sponge metabolites for cytotoxicity and signal transduction activity. |
 60 views 16 downloads |
|---|---|---|
| Name(s): |
Longley, Ross E., creator McConnell, O. J., creator Essich, E., creator Harmody, Dedra K., creator Harbor Branch Oceanographic Institute |
|
| Type of Resource: | text | |
| Genre: | Article | |
| Issuance: | single unit | |
| Date Issued: | 1993 | |
| Publisher: | American Chemical Society | |
| Extent: | 7 p. | |
| Physical Description: | ||
| Language(s): | English | |
| Identifier: | 3318961 (digitool), FADT3318961 (IID), fau:6019 (fedora), 10.1021/np50096a015 (doi) | |
| Note(s): |
Twenty-four metabolites derived from marine sponges were evaluated for their cytotoxicities against two human tumor cell lines, non-small cell lung carcinoma A549 and colon adenocarcinoma HT-29, and against one murine leukemia cell line, P-388, and evaluated for their ability to effect signal transduction in a newly developed cell adhesion assay using an EL-4 cell line. This document is the accepted manuscript version of a published work that appeared in final form in Journal of Natural Products after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/np50096a015. This article may be cited as: Longley, R. E., McConnell, O. J., Essich, E., & Harmody, D. (1993). Evaluation of marine sponge metabolites for cytotoxicity and signal transduction activity. Journal of Natural Products, 56(6), 915-920. doi:10.1021/np50096a015 Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #959. |
|
| Subject(s): |
Marine metabolites Sponges --Research Cell-mediated cytotoxicity Cellular signal transduction |
|
| Persistent Link to This Record: | http://purl.flvc.org/FCLA/DT/3318961 | |
| Links: | http://dx.doi.org/10.1021/np50096a015 | |
| Restrictions on Access: | ©1993 American Chemical Society | |
| Host Institution: | FAU |
