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Development of sponge cell cultures for biomedical application

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Date Issued:
Title: Development of sponge cell cultures for biomedical application.
Name(s): Pomponi, Shirley A., creator
Willoughby, Robin, creator
Type of Resource: text
Genre: Article
Issuance: single unit
Date Issued: 2000
Publisher: Springer-Verlag
Extent: 15 p.
Physical Description: pdf
Language(s): English
Identifier: 3172822 (digitool), FADT3172822 (IID), fau:5686 (fedora)
Note(s): The objective of research in progress in our laboratory is to establish cell lines of bioactive marine invertebrates that can be used as models to study in vitro production of bioactive metabolites and the factors which control expression of production. We hypothesize that understanding the molecular mechanisms involved in growth regulation and bioactive metabolite production in these organisms will lead to the development of genetically engineered cell-lines capable of overexpression of bioactive natural products. Perhaps more important, however, is the development of cell lines of these 'simple' metazoans to study basic cell physiology and molecular biology that may be applied to understanding more complex metazoan systems, including humans.
This manuscript is an author version with the final publication available at and may be cited as: Pomponi, S. A., & Willoughby, R. (2000). Development of sponge cell cultures for biomedical application. In C. Mothersill & B. Austin (Eds.). Aquatic invertebrate cell culture. (pp. 323-336). Berlin: Springer-Verlag.
Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #1343.
Subject(s): Natural products
Bioactive compounds
Sponges --Cytology
Persistent Link to This Record:
Restrictions on Access: ©2000 Springer-Verlag
Host Institution: FAU