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Naturally mosaic operons for secondary metabolite biosynthesis: variability and putative horizontal transfer of discrete catalytic domains of the epothilone polyketide synthase locus

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Date Issued:
2003
Title: Naturally mosaic operons for secondary metabolite biosynthesis: variability and putative horizontal transfer of discrete catalytic domains of the epothilone polyketide synthase locus.
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Name(s): Lopez, Jose V., creator
Harbor Branch Oceanographic Institute
Type of Resource: text
Genre: Article
Issuance: single unit
Date Issued: 2003
Publisher: Springer-Verlag
Extent: 13 p.
Physical Description: pdf
Language(s): English
Identifier: 3166884 (digitool), FADT3166884 (IID), fau:5618 (fedora), 10.1007/s00438-003-0937-9 (doi)
Note(s): This study emphasizes the use of several lines of concordant evidence (phylogenetics, base composition, transposon sequences) to infer the evolutionary history of particular gene and enzyme sequences, and the results support the idea that genes coding for adaptive traits, e.g. defensive natural products, may be prone to transposition between divergent prokaryotic taxa and genomes.
This manuscript is an author version with the final publication available at http://www.springerlink.com and may be cited as: Lopez, J. V. (2003). Naturally mosaic operons for secondary metabolite biosynthesis: variability and putative horizontal transfer of discrete catalytic domains of the epothilone polyketide synthase locus. Molecular Genetics and Genomics, 270(9), 420-431.
Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #1519.
Subject(s): Polyketides
Operons
Peptides --Physiological effect
Genetic transformation
Phylogeny
Persistent Link to This Record: http://purl.flvc.org/FCLA/DT/3166884
Links: http://dx.doi.org/10.1007/s00438-003-0937-9
Restrictions on Access: ©2003 Springer-Verlag
Host Institution: FAU