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Naturally mosaic operons for secondary metabolite biosynthesis: variability and putative horizontal transfer of discrete catalytic domains of the epothilone polyketide synthase locus
| Title: | Naturally mosaic operons for secondary metabolite biosynthesis: variability and putative horizontal transfer of discrete catalytic domains of the epothilone polyketide synthase locus. |
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| Name(s): |
Lopez, Jose V., creator Harbor Branch Oceanographic Institute |
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| Type of Resource: | text | |
| Genre: | Article | |
| Issuance: | single unit | |
| Date Issued: | 2003 | |
| Publisher: | Springer-Verlag | |
| Extent: | 13 p. | |
| Physical Description: | ||
| Language(s): | English | |
| Identifier: | 3166884 (digitool), FADT3166884 (IID), fau:5618 (fedora), 10.1007/s00438-003-0937-9 (doi) | |
| Note(s): |
This study emphasizes the use of several lines of concordant evidence (phylogenetics, base composition, transposon sequences) to infer the evolutionary history of particular gene and enzyme sequences, and the results support the idea that genes coding for adaptive traits, e.g. defensive natural products, may be prone to transposition between divergent prokaryotic taxa and genomes. This manuscript is an author version with the final publication available at http://www.springerlink.com and may be cited as: Lopez, J. V. (2003). Naturally mosaic operons for secondary metabolite biosynthesis: variability and putative horizontal transfer of discrete catalytic domains of the epothilone polyketide synthase locus. Molecular Genetics and Genomics, 270(9), 420-431. Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #1519. |
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| Subject(s): |
Polyketides Operons Peptides --Physiological effect Genetic transformation Phylogeny |
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| Persistent Link to This Record: | http://purl.flvc.org/FCLA/DT/3166884 | |
| Links: | http://dx.doi.org/10.1007/s00438-003-0937-9 | |
| Restrictions on Access: | ©2003 Springer-Verlag | |
| Host Institution: | FAU |
