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Plakolide A, a New γ‐Lactone from the Marine Sponge Plakortis sp.
- Date Issued:
- 2004
Title: | Plakolide A, a New γ‐Lactone from the Marine Sponge Plakortis sp. |
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Name(s): |
Gunasekera, Sarath P., creator Isbrucker, Richard A., creator Longley, Ross E., creator Wright, Amy E., creator Pomponi, Shirley A., creator Reed, John K., creator |
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Type of Resource: | text | |
Genre: | Article | |
Issuance: | single unit | |
Date Issued: | 2004 | |
Publisher: | American Chemical Society and American Society of Pharmacognosy | |
Extent: | 3 p. | |
Physical Description: | ||
Language(s): | English | |
Identifier: | 3164104 (digitool), FADT3164104 (IID), fau:5609 (fedora), 10.1021/np030294c (doi) | |
Note(s): |
Plakolide A (1), a new α-exomethylene-γ-lactone isolated from the marine sponge Plakortis sp., was found to inhibit inducible nitric oxide synthase (iNOS) activity. The isolation, structure elucidation, and biological activity of plakolide A is described. This document is the accepted manuscript version of a published work that appeared in final form in Journal of Natural Products after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/np030294c. This article may be cited as: Gunasekera, S. P., Isbrucker, R. A., Longley, R. E., Wright, A. E., Pomponi, S. A., & Reed, J. K. (2004). Plakolide A, a New γ-Lactone from the Marine Sponge Plakortis sp. Journal of Natural Products, 67(1), 110-111. Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #1536. |
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Subject(s): |
Sponges Lactones Acids Nitric-oxide synthase Nuclear magnetic resonance spectroscopy |
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Persistent Link to This Record: | http://purl.flvc.org/FCLA/DT/3164104 | |
Links: | http://dx.doi.org/10.1021/np030294c | |
Restrictions on Access: | ©2004 American Chemical Society and American Society of Pharmacognosy | |
Host Institution: | FAU |