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New Bioactive Peroxides from Marine Sponges of the Family Plakiniidae
| Title: | New Bioactive Peroxides from Marine Sponges of the Family Plakiniidae. |
 66 views 17 downloads |
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| Name(s): |
Chen, Ying, creator McCarthy, Peter J., creator Harmody, Dedra K., creator Schimoler, Rebecca, creator Chilson, Katherine, creator Selitrennikoff, Claude, creator Pomponi, Shirley A., creator Wright, Amy E., creator |
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| Type of Resource: | text | |
| Genre: | Article | |
| Issuance: | single unit | |
| Date Issued: | 2002 | |
| Publisher: | American Chemical Society and American Society of Pharmacognosy | |
| Extent: | 5 p. | |
| Physical Description: | ||
| Language(s): | English | |
| Identifier: | 3164099 (digitool), FADT3164099 (IID), fau:5606 (fedora), 10.1021/np0200414 (doi) | |
| Note(s): |
In our continuing program to identify compounds with antifungal properties, the ethanol extracts of two sponges of the family Plakinidae were found to inhibit the growth of the fungal pathogens Candida albicans and Aspergillus fumigatus. From these organisms three new compounds and five known compounds have been identified. A new 1,2-dioxane ring peroxide acid, 1, has been isolated from the sponge Plakortis halichondrioides along with five known compounds. Two new 1,2-dioxolane peroxide acids, 3 and 4, have been isolated from the sponge Plakinastrella onkodes. The structures were established by interpretation of spectral data. This document is the accepted manuscript version of a published work that appeared in final form in Journal of Natural Products after peer review and technical editing by the publisher. To access the final edited and published work see http://dx.doi.org/10.1021/np0200414. This article may be cited as: Chen, Y., McCarthy, P. J., Harmody, D. K., Schimoler-O’Rourke, R., Chilson, K., Selitrennikoff, C., Pomponi, S. A., & Wright, A. E. (2002). New Bioactive Peroxides from Marine Sponges of the Family Plakiniidae. Journal of Natural Products, 65(10), 1509-1512. Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #1478. |
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| Subject(s): |
Sponges Peroxides Pathogenic fungi Candida albicans Aspergillus fumigatus |
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| Persistent Link to This Record: | http://purl.flvc.org/FCLA/DT/3164099 | |
| Links: | http://dx.doi.org/10.1021/np0200414 | |
| Restrictions on Access: | ©2002 American Chemical Society and American Society of Pharmacognosy | |
| Host Institution: | FAU |
