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Sterols of the marine sponge Petrosia weinbergi: implications for the absolute configurations of the antiviral orthoesterols and weinbersterols
| Title: | Sterols of the marine sponge Petrosia weinbergi: implications for the absolute configurations of the antiviral orthoesterols and weinbersterols. |
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| Name(s): |
Giner, José-Luis, creator Gunasekera, Sarath P., creator Pomponi, Shirley A., creator |
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| Type of Resource: | text | |
| Genre: | Article | |
| Issuance: | single unit | |
| Date Issued: | 1999 | |
| Publisher: | Elsevier Science Inc. | |
| Extent: | 6 p. | |
| Physical Description: | ||
| Language(s): | English | |
| Identifier: | 3158771 (digitool), FADT3158771 (IID), fau:5599 (fedora), 10.1016/S0039-128X(99)00068-9 (doi) | |
| Note(s): |
The marine sponge Petrosia weinbergi was found to contain isofucosterol and clionasterol as its major sterols. The rare cyclopropyl sterol (24S,28S)-24,28-methylenestigmast-5-en-3b-ol, previously detected as only 0.07% of the total sterols of a pelagophytic alga Pulvinaria sp., made up 6.6% of the total sterols. These sterols are believed to be the biosynthetic precursors of the antiviral orthoesterols and weinbersterols found in the same sponge. Based on the side chains of the isolated sterols, the absolute configurations of the antiviral steroid side chains are assigned to be (24R,28S)- for orthoesterol B, (24R)- for orthoesterol C, and (24S,28S)- for weinbersterols A and B. The final published version of this manuscript is available at http://www.sciencedirect.com/science/journal/0039128X. This article may be cited as: Giner, J.-L., Gunasekera, S. P., & Pomponi, S. A. (1999). Sterols of the marine sponge Petrosia weinbergi: implications for the absolute configurations of the antiviral orthoesterols and weinbersterols. Steroids, 64(12), 820-824. doi:10.1016/S0039-128X(99)00068-9 Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #1328. |
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| Subject(s): |
Sponges Sterols --Analysis Steroids Biosynthesis Marine metabolites |
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| Persistent Link to This Record: | http://purl.flvc.org/FCLA/DT/3158771 | |
| Links: | http://dx.doi.org/10.1016/S0039-128X(99)00068-9 | |
| Restrictions on Access: | ©1999 Elsevier Science Inc. | |
| Host Institution: | FAU |
