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Tubercidin, A Cytotoxic Agent from the Marine Sponge Caulospongia biflabellata

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Date Issued:
2002
Title: Tubercidin, A Cytotoxic Agent from the Marine Sponge Caulospongia biflabellata.
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Name(s): Biabani, Misbah F., creator
Gunasekera, Sarath P., creator
Longley, Ross E., creator
Wright, Amy E., creator
Pomponi, Shirley A., creator
Type of Resource: text
Genre: Article
Issuance: single unit
Date Issued: 2002
Publisher: Swets & Zeitlinger
Extent: 3 p.
Physical Description: pdf
Language(s): English
Identifier: 2795916 (digitool), FADT2795916 (IID), fau:5539 (fedora), 10.1076/phbi.40.4.302.8469 (doi)
Note(s): Tubercidin (1), a known nucleoside antibiotic, was isolated as the major metabolite from a marine sponge Caulospongia biflabellata. Compound 1 exhibited potent cytotoxic activity against P388 and A549 tumor cells. The isolation, structure elucidation and biological activities of tubercidin (1) are described. This is the first report of the isolation of tubercidin from a marine organism.
This author manuscript is an electronic version of an article published in Pharmaceutical Biology and may be cited as Biabani, Misbah F., Sarath P. Gunasekera, Ross E. Longley, Amy E. Wright and Shirley A. Pomponi (2002) Tubercidin, A Cytotoxic Agent from the Marine Sponge Caulospongia biflabellata, Pharmaceutical Biology 40(4):302–303.
Florida Atlantic University. Harbor Branch Oceanographic Institute contribution #1470.
Subject(s): Demospongiae
Nucleosides --chemistry
Cytotoxins --biosynthesis --congresses
Streptomyces
Antitumor antibiotics
Persistent Link to This Record: http://purl.flvc.org/FCLA/DT/2795916
Links: https://doi.org/10.1076/phbi.40.4.302.8469 
Restrictions on Access: ©2002 Swets & Zeitlinger
Host Institution: FAU