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Isolation and Relative Configuration Determination of Two Pairs of Bioactive diastereomers from Cacospongia cf. linteiformis
- Date Issued:
- 2014
- Abstract/Description:
- Cacospongia cf. linteiformis is a marine sponge collected from Bahamas possessing various bioactive compounds. Two pairs of diastereomers spongianolides E&F were isolated for the first time through function group modification acetylation, and their relative configurations were determined based on Nuclear Overhauser Effect Spectroscopy NOESY. The mixture of isomers of spongianolides E&F are exhibiting inhibition against Schnurri-3. Bioassays will be repeated to unveil the assignment of the bioactivities for the four isomers.
Title: | Isolation and Relative Configuration Determination of Two Pairs of Bioactive diastereomers from Cacospongia cf. linteiformis. |
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Name(s): |
Zhang, Long West, Lyndon Graduate College |
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Type of Resource: | text | |
Genre: | Abstract | |
Date Created: | 2014 | |
Date Issued: | 2014 | |
Publisher: | Florida Atlantic University | |
Place of Publication: | Boca Raton, Fla. | |
Physical Form: | application/pdf | |
Extent: | 1 p. | |
Language(s): | English | |
Abstract/Description: | Cacospongia cf. linteiformis is a marine sponge collected from Bahamas possessing various bioactive compounds. Two pairs of diastereomers spongianolides E&F were isolated for the first time through function group modification acetylation, and their relative configurations were determined based on Nuclear Overhauser Effect Spectroscopy NOESY. The mixture of isomers of spongianolides E&F are exhibiting inhibition against Schnurri-3. Bioassays will be repeated to unveil the assignment of the bioactivities for the four isomers. | |
Identifier: | FA00005865 (IID) | |
Collection: | FAU Student Research Digital Collection | |
Note(s): | The Fifth Annual Graduate Research Day was organized by Florida Atlantic University’s Graduate Student Association. Graduate students from FAU Colleges present abstracts of original research and posters in a competition for monetary prizes, awards, and recognition | |
Held by: | Florida Atlantic University Libraries | |
Sublocation: | Digital Library | |
Persistent Link to This Record: | http://purl.flvc.org/fau/fd/FA00005865 | |
Use and Reproduction: | Copyright © is held by the author with permission granted to Florida Atlantic University to digitize, archive and distribute this item for non-profit research and educational purposes. Any reuse of this item in excess of fair use or other copyright exemptions requires permission of the copyright holder. | |
Host Institution: | FAU | |
Is Part of Series: | Florida Atlantic University Digital Library Collections. |