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Fundamental Physics of All-Aqueous Micro-Droplet Generation Mechanisms
- Date Issued:
- 2017
- Summary:
- Aqueous microdroplets have shown great potential in various applications such as material synthesis, chemical reactions, and drug discovery. The objective of this research is to generate aqueous microdroplets in water using microfluidic techniques. Compared to conventional aqueous droplets in an oil phase, droplets generated from the proposed system will be more biocompatible and simply manufactured. To achieve this goal, the research focuses on understanding fundamental physics behind droplet generation at various geometries and input conditions. This understanding can subsequently help us obtain microdroplets with targeted properties. Several microdroplet generators made of polydimethylsiloxane (PDMS) transparent polymer are fabricated and an aqueous two-phase system (ATPS) made up of two water-based polymers, polyethylene glycol (PEG) and dextran (DEX) is used in these generators. The results successfully demonstrate that the proposed droplet generators produce aqueous microdroplets at various sizes at different frequencies. The controllability and tunability of the properties of microdroplets will be discussed.
Title: | Fundamental Physics of All-Aqueous Micro-Droplet Generation Mechanisms. |
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Name(s): |
Melgar Jimenez, Sofia Petrozzi, Nick Mastiani, Mohammad Kim, Mike Office of Undergraduate Research and Inquiry |
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Type of Resource: | text | |
Genre: | Poster | |
Date Created: | 2017 | |
Date Issued: | 2017 | |
Publisher: | Florida Atlantic University | |
Place of Publication: | Boca Raton, Florida | |
Physical Form: | application/pdf | |
Extent: | 1 p. | |
Language(s): | English | |
Summary: | Aqueous microdroplets have shown great potential in various applications such as material synthesis, chemical reactions, and drug discovery. The objective of this research is to generate aqueous microdroplets in water using microfluidic techniques. Compared to conventional aqueous droplets in an oil phase, droplets generated from the proposed system will be more biocompatible and simply manufactured. To achieve this goal, the research focuses on understanding fundamental physics behind droplet generation at various geometries and input conditions. This understanding can subsequently help us obtain microdroplets with targeted properties. Several microdroplet generators made of polydimethylsiloxane (PDMS) transparent polymer are fabricated and an aqueous two-phase system (ATPS) made up of two water-based polymers, polyethylene glycol (PEG) and dextran (DEX) is used in these generators. The results successfully demonstrate that the proposed droplet generators produce aqueous microdroplets at various sizes at different frequencies. The controllability and tunability of the properties of microdroplets will be discussed. | |
Identifier: | FA00005629 (IID) | |
Subject(s): | College students --Research --United States. | |
Held by: | Florida Atlantic University Libraries | |
Sublocation: | Digital Library | |
Persistent Link to This Record: | http://purl.flvc.org/fau/fd/FA00005629 | |
Restrictions on Access: | Author retains rights. | |
Host Institution: | FAU |