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The chemistry and biological activity of five marine sponges of the genus Aplysina
| Title: | The chemistry and biological activity of five marine sponges of the genus Aplysina. |
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| Name(s): |
Gunasekera, Sarath P. Cross, S. S. Longley, Ross E. Pomponi, Shirley A. |
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| Type of Resource: | text | |
| Genre: | Article | |
| Date Issued: | 1991 | |
| Publisher: | University of Illinois | |
| Place of Publication: | Chicago, IL | |
| Physical Form: | ||
| Extent: | 7 p. | |
| Language(s): | English | |
| Identifier: | FA00007303 (IID) | |
| Note(s): |
Four species of the genus Aplysina, namely, A. fistularis fulva, A. archeri, A. lacunosa, and
A. caulijormis have been studied, and fistularin-3 (1) has been identified as a compound active against feline
leukemia virus. Antiviral activity found in the crude extracts was found to correlate to the concentration of
fistularin-3 isolated by an hplc method. Similarly, the immunosuppressive agent in A. fistularis fulva has been
isolated and identified as aerothionin (2). These two compounds have been reported previously from the genus
Aplysina. This is the first report confirming the antiviral activity detected in different species of Aplysina with
the presence of fistularin-3. Florida Atlantic University. Harbor Branch Oceanographic Institute contribution 899 This manuscript is an author version with the final publication available and may be cited as: Gunasekera, S. P., Cross, S. S., Longley, R. E., & Pomponi, S. A. (1991). The chemistry and biological activity of five marine sponges of the genus Aplysina. In J. M. Pezzuto, A. D. Kinghorn, H. H. S. Fong, & G. A. Cordell (Eds.), Progress on terrestrial and marine natural products of medicinal and biological interest: proceedings of a symposium held on the occasion of the 60th birthday of Norman R. Farnsworth (pp. 53-58). Chicago, IL: University of Illinois. |
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| Subject(s): |
Sponges Antiviral agents Immunosuppressive agents Bioactive compounds Marine natural products |
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| Persistent Link to This Record: | http://purl.flvc.org/fau/fd/FA00007303 | |
| Host Institution: | FAU |
