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Cross-reactivity between immunoglobulin G antibodies of whales and dolphins correlates with evolutionary distance
| Title: | Cross-reactivity between immunoglobulin G antibodies of whales and dolphins correlates with evolutionary distance. |
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| Name(s): |
Nollens, H. H. Ruiz, C. Walsh, M. T. Gulland, F. M. D. Bossart, Gregory D. Jensen, Eric D. McBain, J. F. Wellehan, J. F. X. Harbor Branch Oceanographic Institute |
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| Type of Resource: | text | |
| Genre: | Article | |
| Date Issued: | 2008 | |
| Publisher: | American Society for Microbiology | |
| Place of Publication: | Washington, D.C. | |
| Physical Form: | ||
| Extent: | 9 p. | |
| Language(s): | English | |
| Identifier: | FA00007248 (IID), 10.1128/CVI.00219-08 (doi) | |
| Note(s): |
Growing morphological and molecular evidence indicates that the porpoises, dolphins, and whales evolvedwithin the even-toed ungulates, formerly known as Artiodactyla. These animals are now grouped in theCetartiodactyla. We evaluated the antigenic similarity of the immunoglobulin G (IgG) molecules of 15 cetaceanspecies and the domestic cow. The similarity was scored using three distinct antibodies raised againstbottlenose dolphin (Tursiops truncatus) IgG in a Western blot, an indirect enzyme-linked immunosorbent assay(ELISA), and a competitive ELISA format. A score was generated for the genetic distance between each speciesand T. truncatus using the cytochrome b sequence. Each antibody displayed a distinct pattern of reactivity withthe IgG antibodies of the various species. Florida Atlantic University. Harbor Branch Oceanographic Institute contribution 1719 This manuscript is an author version with the final publication available and may be cited as: Nollens, H. H., Ruiz, C., Walsh, M. T., Gulland, F. M. D., Bossart, G., Jensen, E. D., McBain, J. F., & Wellehan, J. F. X. (2008). Cross-reactivity between immunoglobulin G antibodies of whales and dolphins correlates with evolutionary distance. Clinical and Vaccine Immunology, 15(10), 1547-1554. doi: 10.1128/CVI.00219-08. |
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| Subject(s): |
Whales Dolphins Immunoglobulin G Antibodies Cetacea |
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| Persistent Link to This Record: | http://purl.flvc.org/fau/fd/FA00007248 | |
| Links: | http://dx.doi.org/10.1128/CVI.00219-08 | |
| Host Institution: | FAU |
