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Altered in vitro immune responses in green turtles (Chelonia mydas) with fibropapillomatosis
| Title: | Altered in vitro immune responses in green turtles (Chelonia mydas) with fibropapillomatosis. |
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| Name(s): |
Cray, C. Varela, Rene A. Bossart, Gregory D. Lutz, Peter L. Harbor Branch Oceanographic Institute |
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| Type of Resource: | text | |
| Genre: | Article | |
| Date Issued: | 2001 | |
| Publisher: | American Association of Zoo Veterinarians | |
| Place of Publication: | Lawrence, KS | |
| Physical Form: | ||
| Extent: | 6 p. | |
| Language(s): | English | |
| Identifier: | FA00007242 (IID) | |
| Note(s): |
The immune competence of green sea turtles (Chelonia mydas) with fibropapillomatosis was assessed using in vitro techniques to measure lymphocyte proliferation in response to mitogens. In comparison with captive, healthy green sea turtles, those afflicted with fibropapillomas demonstrated diminished proliferation with Concanavalin A, phytohemagglutinin (T-cell mitogens), and lipopolysaccharide (B-cell mitogen). Also, markedly decreased proliferative responses to the lymphocyte polyclonal stimulator combination of ionomycin and phorbol myristate acetate were observed. Total circulating white blood cell counts were not statistically different between the two groups, although an overall decrease in lymphocyte number was observed in the papilloma group. The albumin/globulin ratio was decreased in the papilloma group because of decreased albumin and increased gamma globulins. Florida Atlantic University. Harbor Branch Oceanographic Institute contribution 1493 This manuscript is an author version with the final publication available and may be cited as: Cray, C., Varela, R., Bossart, G. D., & Lutz, P. (2001). Altered in vitro immune responses in green turtles (Chelonia mydas) with fibropapillomatosis. Journal of Zoo and Wildlife Medicine, 32(4), 436-440. |
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| Subject(s): |
Green turtle Chelonia mydas Papilloma Immune system |
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| Persistent Link to This Record: | http://purl.flvc.org/fau/fd/FA00007242 | |
| Host Institution: | FAU |
