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Marine organisms as a source of novel lead structures for drug development
| Title: | Marine organisms as a source of novel lead structures for drug development. |
 113 views 38 downloads |
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| Name(s): | Wright, Amy E. | |
| Type of Resource: | text | |
| Genre: | Article | |
| Date Issued: | 2000 | |
| Publisher: | Royal Society of Chemistry | |
| Place of Publication: | Cambridge | |
| Physical Form: | ||
| Extent: | 15 p. | |
| Language(s): | English | |
| Identifier: | FA00007060 (IID), 10.1039/9781847550231-00113 (doi) | |
| Note(s): |
Screening of extracts obtained from terrestrial plants and animals has yielded a large number of novel natural products. Many of these have been developed into useful, medicinal agents either directly as the natural product or through synthetic modification. It has been estimated that for the period 1983-1994, 78% of the antibacterial agents and 61% of the 31 anticancer agents approved for use, were derived from terrestrial natural products. By comparison the marine environment remains relatively unexplored. The oceans cover over 70% of the Earth's surface. Estimates of the number of marine invertebrate and algal species are at least 200,000, while those for marine microbial strains range into the millions. Florida Atlantic University. Harbor Branch Oceanographic Institute contribution 1345 This manuscript is an author version with the final publication available and may be cited as: Wright, A. E. (2000). Marine organisms as a source of novel lead structures for drug development. In S. E. Wrigley, M. A. Hayes, R. Thomas, E. J. T. Chrystal & N. Nicholson (Eds.), Biodiversity: New leads for the pharmaceutical and agrochemical Industries (113-125). Cambridge: Royal Society of Chemistry. |
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| Subject(s): |
Marine organisms Marine natural products Drug development |
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| Persistent Link to This Record: | http://purl.flvc.org/fau/fd/FA00007060 | |
| Links: | http://dx.doi.org/10.1039/9781847550231-00113 | |
| Host Institution: | FAU |
