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Effects of acute and chronic cocaine on milk intake, body weight, and activity in bottle- and cannula-fed rats
| Title: | Effects of acute and chronic cocaine on milk intake, body weight, and activity in bottle- and cannula-fed rats. |
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| Name(s): |
Wolgin, David L., creator Hertz, Jacqueline Moore, creator |
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| Type of Resource: | text | |
| Genre: | Article | |
| Issuance: | single unit | |
| Date Issued: | 1995-01-01 | |
| Publisher: | Lippincott-Raven Publishers | |
| Language(s): | English | |
| Identifier: | 228753 (digitool), FADT228753 (IID), fau:2639 (fedora) | |
| FAU Department/College: | Department of Psychology Charles E. Schmidt College of Science | |
| Note(s): |
The effects of cocaine on the milk intake, body weight and activity of bottle- and cannula-fed rats was compared under both acute and chronic dosing conditions. Bottle-fed rats were initially more hypophagic than cannula-fed rats when given acute injections of cocaine (4-40 mg/kg). Following chronic injections of the drug (16 mg/kg), bottle-fed rats developed tolerance, as shown by a rightward shift in the dose-response function for milk intake. Such tolerance was accompanied by a decrease in drug-induced motor activity. In contrast, cannula-fed rats showed marked sensitization of stereotyped movements. Bottle-fed rats showed marked sensitization of stereotyped movements. This is a non-final version of an article published in final form in Behavioural Pharmacology (November 1995) v.6, no. 7 p. 643-754. The original publication is available at http://journals.lww.com/behaviouralpharm/toc/1995/11000 |
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| Subject(s): |
Behavior--drug effects. Psychopharmacology--Animal models. Psychopharmacology--Research. |
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| Persistent Link to This Record: | http://purl.flvc.org/fau/228753 | |
| Restrictions on Access: | ©1995 Lippincott-Raven Publishers | |
| Host Institution: | FAU |
