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Cortical KCI reinstates forelimb placing following damage to the internal capsule

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Date Issued:
1983-08
Title: Cortical KCI reinstates forelimb placing following damage to the internal capsule.
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Name(s): Wolgin, David L., creator
Kehoe, Priscilla, creator
Type of Resource: text
Genre: Article
Issuance: single unit
Date Issued: 1983-08
Publisher: Elsevier
Language(s): English
Identifier: 228749 (digitool), FADT228749 (IID), fau:2637 (fedora), 10.1016/0031-9384(83)90118-X (doi)
FAU Department/College: Department of Psychology Charles E. Schmidt College of Science
Note(s): Following unilateral damage to the internal capsule, rats failed to use the contralateral forelimb during tests of contact, chin, and visual placing reactions. Infusion of potassium chloride onto the sensorimotor cortex contralateral to the lesion reinstated placing in the impaired limb and abolished placing in the normal limb. As the drug dissipated, placing in the impaired limb gradually deteriorated, while placing in the normal limb returned. In contrast, potassium chloride applied to the ipsilateral cortex did not reinstate placing. These findings suggest that the loss of forelimb placing following lesions of the internal capsule is due, at least in part, to tonic inhibition from the cortex contralateral to the lesions.
This manuscript is a version of an article published in Physiology & Behavior v. 31, no. 2 (August 1983) p. 197-202. The published article is available at www.sciencedirect.com
Subject(s): Physiology--Research.
Drugs Physiological effect
Persistent Link to This Record: http://purl.flvc.org/fau/228749
Links: http://dx.doi.org/10.1016/0031-9384(83)90118-X
Restrictions on Access: ©1983 Elsevier Inc.
Host Institution: FAU

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