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Long-term retention of tolerance to amphetamine hypophagia following cessation of drug injections and feeding tests
| Title: | Long-term retention of tolerance to amphetamine hypophagia following cessation of drug injections and feeding tests. |
 97 views 32 downloads |
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| Name(s): |
Wolgin, David L., creator Hughes, Katherine M., creator |
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| Type of Resource: | text | |
| Genre: | Article | |
| Issuance: | single unit | |
| Date Issued: | 2001-10 | |
| Publisher: | Elsevier Science Inc. | |
| Language(s): | English | |
| Identifier: | 228747 (digitool), FADT228747 (IID), fau:2636 (fedora), 10.1016/S0091-3057(01)00622-0 (doi) | |
| FAU Department/College: | Department of Psychology Charles E. Schmidt College of Science | |
| Note(s): |
According to the instrumental learning model, tolerance to amphetamine hypophagia involves learning to suppress stereotyped movements that interfere with feeding. If both drug injections and feeding tests are then suspended, learning should be retained and no loss of tolerance should occur. However, previous studies have only assessed the retention of tolerance for 3–4 weeks. In the present study, retention intervals of 4–31 weeks were used. Rats were given daily injections of amphetamine (2 mg/kg) and access to milk for 30 min until tolerance developed to drug-induced hypophagia. This manuscript is a version of an article published in Pharmacology Biochemistry and Behavior v. 70, no. 2-3 (October-November 2001) p. 367-373. The published article is available at www.elsevier.com/locate/pharmbiochembeh |
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| Subject(s): |
Psychopharmacology--Research. Amphetamines--Physiological effects. Appetite depressants. |
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| Persistent Link to This Record: | http://purl.flvc.org/fau/228747 | |
| Links: | http://dx.doi.org/10.1016/S0091-3057(01)00622-0 | |
| Restrictions on Access: | ©2001 Elservier Science, Inc. | |
| Host Institution: | FAU |
