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Expression of c-fos mRNA in the basal ganglia associated with contingent tolerance to amphetamine-induced hypophagia
| Title: | Expression of c-fos mRNA in the basal ganglia associated with contingent tolerance to amphetamine-induced hypophagia. |
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| Name(s): |
Wolgin, David L., creator Bachand, Kimberlee D., creator Guthrie, Kathleen M., creator |
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| Type of Resource: | text | |
| Genre: | Article | |
| Issuance: | single unit | |
| Date Issued: | 2009-03-17 | |
| Publisher: | Elsevier B.V. | |
| Language(s): | English | |
| Identifier: | 228630 (digitool), FADT228630 (IID), fau:2632 (fedora), 10.1016/j.bbr.2008.11.026 (doi) | |
| FAU Department/College: | Department of Psychology Charles E. Schmidt College of Science | |
| Note(s): |
Tolerance to the hypophagic effect of psychostimulants is contingent on having access to food while intoxicated. Rats given chronic injections of such drugs with access to food learn to suppress stereotyped movements, which interfere with feeding. In contrast, controls given the drug after food access do not learn to suppress stereotypy and, therefore, do not become tolerant. To determine the role of the basal ganglia in this phenomenon, we used in situ hybridization to measure the expression of c-fos mRNA, a marker for neural activation, in the brains of tolerant and nontolerant rats. This manuscript is a version of an article published in Behavioural Brain Research, v. 198, no. 2 (2009) 388–396 . The published article can be found at www.elsevier.com/locate/bbr |
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| Subject(s): |
Psychopharmacology--Research. Pharmacology--Research--Methodology. Neurosciences--Research--Methodology. Animal experimentation. |
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| Persistent Link to This Record: | http://purl.flvc.org/fau/228630 | |
| Links: | http://dx.doi.org/10.1016/j.bbr.2008.11.026 | |
| Restrictions on Access: | ©2008 Elsevier B.V. | |
| Host Institution: | FAU |
