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Role of anorexia and behavioral activation in amphetamine-induced suppression of feeding: implications for understanding tolerance
| Title: | Role of anorexia and behavioral activation in amphetamine-induced suppression of feeding: implications for understanding tolerance. |
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| Name(s): |
Wolgin, David L., creator Salisbury, Juanita J., creator |
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| Type of Resource: | text | |
| Genre: | Article | |
| Issuance: | single unit | |
| Date Issued: | 1985 | |
| Publisher: | American Psychological Association | |
| Language(s): | English | |
| Identifier: | 228483 (digitool), FADT228483 (IID), fau:2626 (fedora), 10.1037/0735-7044.99.6.1153 (doi) | |
| FAU Department/College: | Department of Psychology Charles E. Schmidt College of Science | |
| Note(s): |
In order to gain further insight into the mechanism of contingent tolerance to amphetamine anorexia (Carlton & Wolgin, 1971), an attempt was made to determine the role of anorexia and behavioral activation (increased locomotion and/or stereotypy) in the initial suppression of feeding produced by the drug. Rats administered chronic injections of either saline or amphetamine (2 or 4 mg/kg) were given milk either directly into the mouth through an intraoral cannula or in a standard drinking tube. It was reasoned that although drug-induced anorexia would affect intake with both methods of feeding to the same degree, the disruptive effect of behavioral activation would be greater in bottle-fed rats. The results revealed that bottle-fed rats given amphetamine showed substantially greater suppression of intake than cannula-fed rats. This manuscript is a version of an article published in Behavioral Neuroscience 1986, 99(6):1153-1161. This article may not exactly replicate the final version published in the APA journal. It is not the copy of record. The APA Journal may be found at http://www.apa.org/journals/ |
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| Subject(s): |
Psychopharmacology--Research Amphetamines--Physiological effects. Animal experimentation. |
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| Persistent Link to This Record: | http://purl.flvc.org/fau/228483 | |
| Links: | http://dx.doi.org/10.1037/0735-7044.99.6.1153 | |
| Restrictions on Access: | ©1985 American Psychological Association | |
| Host Institution: | FAU |
